1 | ACETYLSALICYLIC ACID | 1件: Acetylsalicylic acid Acetylsalicylic acid | 1件: D00109
D00109
| 2件: PTGS1 PTGS1, PTGS2 💬 | 23件: Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | 4件: 13 13, 46, 51, 210 |
2 | ACT-064992 | - | - | - | - | 5件: 51 51, 85, 86, 88, 210 |
3 | Administration of an ACE-inhibitor or not | - | - | - | - | 1件: 210 210 |
4 | Aesculus Hippocastanum / Horse Chestnut | 1件: Horse chestnut Horse chestnut | 1件: D12028
D12028
| - | - | 1件: 210 210 |
5 | Ambrisentan | 1件: Ambrisentan Ambrisentan | 1件: D07077
D07077
| 1件: EDNRA EDNRA 💬 | 7件: Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 7件: 51 51, 84, 85, 86, 88, 210, 211 |
6 | Arginine | 1件: Arginine Arginine | 1件: D02982
D02982
| - | - | 11件: 46 46, 58, 67, 78, 96, 97, 98, 113, 210, 251, 299 |
7 | Aspirin | 1件: Acetylsalicylic acid Acetylsalicylic acid | 1件: D00109
D00109
| 2件: PTGS1 PTGS1, PTGS2 💬 | 23件: Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | 12件: 13 13, 22, 34, 46, 49, 51, 58, 86, 113, 158, 210, 231 |
8 | Autologous Tissue-Engineered Vascular Graft | - | - | - | - | 1件: 210 210 |
9 | BAY 59-7939 | - | - | - | - | 1件: 210 210 |
10 | Bosentan | 1件: Bosentan Bosentan | 2件: D01227
D01227
,
D07538
| 2件: EDNRA EDNRA, EDNRB 💬 | 9件: Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 11件: 13 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 |
11 | Carvedilol | 1件: Carvedilol Carvedilol | 2件: D00255
D00255
,
D03415
| 5件: ADRA1A ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 | 13件: AMPK signaling pathway AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 5件: 6 6, 57, 86, 113, 210 |
12 | Colchicine | 1件: Colchicine Colchicine | 1件: D00570
D00570
| 9件: TUBB TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 | 10件: Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬 | 7件: 2 2, 42, 46, 56, 93, 210, 266 |
13 | Digoxin | 1件: Digoxin Digoxin | 1件: D00298
D00298
| 4件: ATP1A1 ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 | 18件: Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 3件: 8 8, 46, 210 |
14 | Enalapril | 1件: Enalapril Enalapril | 2件: D00621
D00621
,
D07892
| 1件: ACE ACE 💬 | 6件: Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | 6件: 19 19, 46, 66, 113, 210, 222 |
15 | Eplerenone | 1件: Eplerenone Eplerenone | 1件: D01115
D01115
| 1件: NR3C2 NR3C2 💬 | 1件: Aldosterone-regulated sodium reabsorption Aldosterone-regulated sodium reabsorption 💬 | 4件: 75 75, 113, 210, 215 |
16 | Horse chestnut | 1件: Horse chestnut Horse chestnut | 1件: D12028
D12028
| - | - | 1件: 210 210 |
17 | JNJ-39039039 | - | - | - | - | 1件: 210 210 |
18 | Liothyronine | 1件: Liothyronine Liothyronine | 2件: D01011
D01011
,
D08128
| 2件: THRA THRA, THRB 💬 | 2件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬 | 3件: 13 13, 210, 212 |
19 | Liothyronine I 131 | 2件: Liothyronine Liothyronine, Liothyronine I-131 | 2件: D01011
D01011
,
D08128
| 2件: THRA THRA, THRB 💬 | 2件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬 | 2件: 210 210, 212 |
20 | Macitentan | 1件: Macitentan Macitentan | 1件: D10135
D10135
| 2件: EDNRA EDNRA, EDNRB 💬 | 9件: Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 5件: 51 51, 85, 86, 88, 210 |
21 | Milk | 1件: Cow milk Cow milk | - | - | - | 2件: 98 98, 210 |
22 | MPC | - | - | - | - | 2件: 210 210, 211 |
23 | Mysildecard | - | - | - | - | 1件: 210 210 |
24 | MZ101 | - | - | - | - | 1件: 210 210 |
25 | Nitric Oxide | 1件: Nitric Oxide Nitric Oxide | 1件: D00074
D00074
| - | - | 8件: 46 46, 85, 86, 98, 210, 251, 294, 299 |
26 | Normal Saline | - | - | - | - | 18件: 6 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299 |
27 | ODSH at 0.125 mg/kg/h | - | - | - | - | 1件: 210 210 |
28 | ODSH at 0.250 mg/kg/h | - | - | - | - | 1件: 210 210 |
29 | ODSH at 0.375 mg/kg/h | - | - | - | - | 1件: 210 210 |
30 | Opsumit | 1件: Macitentan Macitentan | 1件: D10135
D10135
| 2件: EDNRA EDNRA, EDNRB 💬 | 9件: Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 3件: 86 86, 88, 210 |
31 | Opsumit® | 1件: Macitentan Macitentan | 1件: D10135
D10135
| 2件: EDNRA EDNRA, EDNRB 💬 | 9件: Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 3件: 86 86, 88, 210 |
32 | Other: Human Milk Derived Fortifier | 1件: Cow milk Cow milk | - | - | - | 1件: 210 210 |
33 | Other: Human/Bovine Milk | 1件: Cow milk Cow milk | - | - | - | 1件: 210 210 |
34 | Rexlemestrocel-L | - | - | - | - | 2件: 210 210, 211 |
35 | Rivaroxaban | 1件: Rivaroxaban Rivaroxaban | 1件: D07086
D07086
| 1件: F10 F10 💬 | 1件: Complement and coagulation cascades Complement and coagulation cascades 💬 | 5件: 46 46, 49, 75, 91, 210 |
36 | SCRM001_TEVG | - | - | - | - | 1件: 210 210 |
37 | Sildenafil | 1件: Sildenafil Sildenafil | 2件: D02229
D02229
,
D08514
| 1件: PDE5A PDE5A 💬 | 3件: Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | 17件: 6 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 |
38 | Sildenafil by injection | 1件: Sildenafil Sildenafil | 2件: D02229
D02229
,
D08514
| 1件: PDE5A PDE5A 💬 | 3件: Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | 1件: 210 210 |
39 | Spironolactone | 1件: Spironolactone Spironolactone | 1件: D00443
D00443
| 1件: NR3C2 NR3C2 💬 | 1件: Aldosterone-regulated sodium reabsorption Aldosterone-regulated sodium reabsorption 💬 | 7件: 58 58, 67, 86, 113, 210, 218, 225 |
40 | Spironolactone (drug) | 1件: Spironolactone Spironolactone | 1件: D00443
D00443
| 1件: NR3C2 NR3C2 💬 | 1件: Aldosterone-regulated sodium reabsorption Aldosterone-regulated sodium reabsorption 💬 | 1件: 210 210 |
41 | Sugar pill | - | - | - | - | 8件: 5 5, 6, 49, 67, 70, 86, 206, 210 |
42 | Tadalafil | 1件: Tadalafil Tadalafil | 1件: D02008
D02008
| 1件: PDE5A PDE5A 💬 | 3件: Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | 7件: 6 6, 51, 75, 84, 86, 113, 210 |
43 | Tadalafil Citrate | 1件: Tadalafil Tadalafil | 1件: D02008
D02008
| 1件: PDE5A PDE5A 💬 | 3件: Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | 1件: 210 210 |
44 | Tracleer | 1件: Bosentan Bosentan | 2件: D01227
D01227
,
D07538
| 2件: EDNRA EDNRA, EDNRB 💬 | 9件: Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | 8件: 13 13, 51, 84, 85, 86, 88, 210, 211 |
45 | Treprostinil | 1件: Treprostinil Treprostinil | 1件: D06213
D06213
| 1件: PTGIR PTGIR 💬 | 3件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | 6件: 51 51, 84, 85, 86, 88, 210 |
46 | Udenafil | 1件: Udenafil Udenafil | 1件: D10027
D10027
| 1件: PDE5A PDE5A 💬 | 3件: Metabolic pathways Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬 | 2件: 86 86, 210 |
47 | Vasopressin | 1件: Vasopressin Vasopressin | 1件: D00101
D00101
| 3件: AVPR1A AVPR1A, AVPR1B, AVPR2 💬 | 5件: Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬 | 1件: 210 210 |
48 | Vasopressin, Arginine | 2件: Arginine Arginine, Vasopressin | 2件: D00101
D00101
,
D02982
| 3件: AVPR1A AVPR1A, AVPR1B, AVPR2 💬 | 5件: Calcium signaling pathway Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬 | 1件: 210 210 |
49 | Vitamin C | 1件: Ascorbic acid Ascorbic acid | 1件: D00018
D00018
| - | - | 6件: 10 10, 192, 206, 210, 211, 212 |
50 | Xarelto | 1件: Rivaroxaban Rivaroxaban | 1件: D07086
D07086
| 1件: F10 F10 💬 | 1件: Complement and coagulation cascades Complement and coagulation cascades 💬 | 2件: 49 49, 210 |