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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(R)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4- yl)pyridine-2-yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate sesquisuccinate1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 ,
D05486 ,
D06224 		--1件: 272
2(R)-tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4- yl)pyridine-2yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 ,
D05486 ,
D06224 		--1件: 272
3AZD0530----1件: 272
4AZD0530 Difumarate----1件: 272
5DS-6016a----1件: 272
6Garetosmab1件: Garetosmab1件: D11443 --1件: 272
7INCB000928----1件: 272
8INCB000928 fumarate dihydrate----1件: 272
9IPN60120----1件: 272
10IPN60130----1件: 272
11IPN60130 10 mg capsules----1件: 272
12IPN60130 50 mg capsules----1件: 272
13Midazolam1件: Midazolam3件: D00550 ,
D00696 ,
D05028 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
14PALOVAROTENE1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
15PALOVAROTENE - 1.5mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
16PALOVAROTENE - 10 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
17PALOVAROTENE - 1mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
18PALOVAROTENE - 2 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
19PALOVAROTENE - 2.5 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
20PALOVAROTENE - 3 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
21PALOVAROTENE - 4 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
22PALOVAROTENE - 5 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
23PALOVAROTENE 1.5 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
24Palovarotene dose level 11件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
25Palovarotene dose level 21件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
26Palovarotene dose level 31件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
27Palovarotene dose level 41件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
28PALOVAROTENE-2 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
29PALOVAROTENE-3 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
30PALOVAROTENE-4 mg1件: Palovarotene1件: D09365 1件: RARG 💬-1件: 272
31Perhexiline1件: Perhexiline2件: D05442 ,
D08340 		8件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CPT1A,
CPT1B,
CPT1C,
CPT2 💬		47件: AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 58, 272
32Piperazine1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 ,
D05486 ,
D06224 		--2件: 58, 272
33REGN2477----1件: 272
34Saracatinib1件: Saracatinib1件: D09664 2件: ABL1,
SRC 💬		49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272
35SARACATINIB DIFUMARATE1件: Saracatinib1件: D09664 2件: ABL1,
SRC 💬		49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬1件: 272