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No. 薬物名(臨床試験情報から抽出) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1ABP 959----1件: 62
2ABP 959 - biosimilar to eculizumab1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
3ABP 959 - proposed biosimilar to eculizumab1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
4ACH-0144471----2件: 62, 222
5ACH-0145228----1件: 62
6Act-HiB1件: Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---4件: 14, 61, 62, 222
7ACT-HIB Polvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml1件: Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---2件: 61, 62
8ActHIB1件: Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---2件: 62, 66
9ACTHIB - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONCINO POLVERE+1 SIRINGA PRERIEMPITA SOLVENTE 0.5 ML1件: Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen---2件: 62, 66
10Allogeneic Bone Marrow Transplantation----9件: 60, 62, 65, 96, 164, 283, 284, 285, 286
11Allogeneic hematopoietic stem cell transplantation----8件: 28, 51, 60, 62, 65, 164, 284, 285
12Allogeneic stem cell transplantation----5件: 19, 20, 49, 62, 84
13ALN-62643----2件: 62, 109
14ALN-CC5----4件: 11, 62, 66, 109
15ALXN1102----1件: 62
16ALXN1103----1件: 62
17ALXN1210----7件: 2, 11, 13, 50, 62, 66, 109
18ALXN2040----1件: 62
19ALXN2040 (ACH-0144471)----1件: 62
20ALXN2050----2件: 11, 62
21Anti-C5 antibody----4件: 11, 14, 62, 109
22Anti-Thymocyte Globulin----18件: 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285
23APL-2----5件: 2, 61, 62, 66, 222
24ARO-C3----2件: 62, 66
25BCD-148----1件: 62
26BCX9930----3件: 62, 66, 222
27BCX9930 hydrochloride----3件: 62, 66, 222
28BCX9930 monotherapy----1件: 62
29Bexsero1件: Neisseria meningitidis serogroup b nhba fusion protein antigen---6件: 11, 13, 61, 62, 66, 222
30BEXSERO - SOSPENSIONE INIETTABILE - USO INTRAMUSCOLARE - SIRINGA P1件: Neisseria meningitidis serogroup b nhba fusion protein antigen---1件: 62
31BEXSERO – Sospensione iniettabile – Siringa preriempita1件: Neisseria meningitidis serogroup b nhba fusion protein antigen---2件: 61, 62
32Bryostatin 11件: Bryostatin 1---1件: 62
33C5 inh MAb, SKY59, RO/CH7092230----2件: 62, 109
34C5 Inhibitor----1件: 62
35Campath1件: Alemtuzumab1件: D02802 1件: CD52 💬-12件: 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326
36Campath, Chemo and/or TBI Allo SCT1件: Alemtuzumab1件: D02802 1件: CD52 💬-3件: 60, 62, 283
37Cemdisiran1件: Cemdisiran---4件: 11, 62, 66, 109
38COVERSIN1件: Nomacopan1件: D11473 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 62, 109
39CROVALIMAB1件: Crovalimab1件: D11696 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 62, 109
40Cyclophosphamide1件: Cyclophosphamide2件: D00287 ,
D07760
--45件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
41Cyclosporin1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬17件: 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
42Cyclosporin A1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬11件: 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164
43Cyclosporin A+Glucocorticoids1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 60, 62
44Cyclosporine1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
45Cytoreductive regimen followed by a CD34+E- selected allogeneic stem cell transplant----1件: 62
46DANICOPAN1件: Danicopan1件: D11641 1件: CFD 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬2件: 62, 222
47Danicopan (ALXN2040)1件: Danicopan1件: D11641 1件: CFD 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬1件: 62
48Dextran1件: Dextran1件: D00060 --5件: 2, 62, 79, 96, 97
49ECULIZUMAB1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬7件: 11, 13, 14, 61, 62, 109, 222
50Elizaria®----2件: 62, 109
51Fc- and CDR-modified humanised monoclonal antibody against C5----3件: 11, 62, 109
52Filgrastim1件: Filgrastim1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬28件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331
53Fludarabine1件: Fludarabine2件: D01907 ,
D07966
1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬18件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
54Fludarabine phosphate2件: Fludarabine,
Phosphate ion
2件: D01907 ,
D07966
1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬12件: 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286
55G-CSF1件: Filgrastim1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬16件: 2, 6, 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331
56Gelatin1件: Gelatin2件: D00115 ,
D06892
--5件: 28, 62, 78, 97, 269
57Glucocorticoids----8件: 40, 41, 43, 44, 60, 62, 75, 300
58H5G1.1-mAb----3件: 13, 50, 62
59HAEMOPHILUS INFLUENZAE----3件: 61, 62, 66
60Hiberix1件: Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen---4件: 13, 61, 62, 66
61HIBERIX - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO INTRAMUSCOLARE 1 FLACONCINO DI POLVERE + 1 SIRINGA PRERIEMPITA DI SOLVENTE DA 0.5 ML1件: Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen---3件: 61, 62, 66
62Human monoclonal antibody directed against complement 5 protein----1件: 62
63Iptacopan1件: Iptacopan1件: D12251 1件: CFB 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬5件: 61, 62, 66, 109, 222
64Iptacopan (LNP023)1件: Iptacopan1件: D12251 1件: CFB 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬1件: 62
65Iron Dextran2件: Dextran,
Iron Dextran
2件: D00060 ,
D02141
--1件: 62
66Iron sucrose2件: Iron sucrose,
Sucrose
2件: D00025 ,
D04616
--3件: 62, 96, 97
67L04AA25----1件: 62
68Lapine T-Lymphocyte Immune Globulin1件: Antithymocyte immunoglobulin (rabbit)---4件: 62, 65, 283, 286
69Levamisole1件: Levamisole2件: D00750 ,
D08114
--3件: 60, 61, 62
70Levamisole+cyclosporin A+Glucocorticoids2件: Cyclosporine,
Levamisole
3件: D00184 ,
D00750 ,
D08114
5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 60, 62
71LFG316----1件: 62
72LNP023----5件: 61, 62, 66, 109, 222
73LNP023 HYDROCHLORIDE SALT----1件: 62
74Melphalan1件: Melphalan1件: D00369 --15件: 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
75Menveo1件: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine---6件: 11, 13, 61, 62, 66, 222
76MENVEO - POLV.E SOLUZ.PER SOLUZ. INIETT.-USO INTRAMUSCOLARE-COMP. CONIUG.LIOFILIZZ.MENA:FLAC.(VETRO) COMP. GONIUG.LIQUI.MENCWY:FLAC.(VETRO)-1 FLAC+1FLAC1件: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine---2件: 62, 66
77MENVEO – Polvere e soluzione per soluzione iniettabile1件: Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine---2件: 61, 62
78Methotrexate1件: Methotrexate2件: D00142 ,
D02115
2件: DHFR,
DHFR2 💬
5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
79Methylprednisolone1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002
1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
80Miltenyi Biotec CliniMACS----2件: 62, 326
81Miltenyi CliniMACS----3件: 62, 65, 285
82Mycophenolate1件: Mycophenolic acid1件: D05096 2件: IMPDH1,
IMPDH2 💬
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
83Mycophenolate mofetil2件: Mycophenolate mofetil,
Mycophenolic acid
4件: D00752 ,
D05094 ,
D05095 ,
D05096
2件: IMPDH1,
IMPDH2 💬
3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
84Myeloablative Preparative Regimen----3件: 62, 65, 284
85NO----12件: 6, 13, 46, 58, 62, 86, 96, 97, 222, 226, 299, 321
86Nonmyeloablative allogeneic hematopoietic stem cell transplantation----6件: 28, 51, 60, 62, 65, 285
87Other: Blood collection for measurement of eculizumab peak concentrations1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
88Other: Laboratory Biomarker Analysis----21件: 11, 13, 14, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 205, 232, 283, 284, 285, 298, 331
89Other: Peripheral Blood Stem Cells----2件: 60, 62
90Other: Pharmacological Study----7件: 28, 34, 62, 74, 89, 232, 331
91Other: Quality-of-Life Assessment----9件: 34, 36, 51, 62, 65, 96, 283, 286, 298
92Other: Standard of care (SOC)----1件: 62
93PEGCETACOPLAN1件: Pegcetacoplan1件: D11613 1件: C3 💬17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬3件: 2, 62, 222
94Pegcetacoplan (APL-2)1件: Pegcetacoplan1件: D11613 1件: C3 💬17件: Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬2件: 2, 62
95Peripheral Blood Stem Cell Transplantation----12件: 11, 13, 14, 28, 51, 60, 62, 65, 283, 284, 285, 286
96Phosphate1件: Phosphate ion---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
97PNEUMOVAX – Soluzione iniettabile in siringa preriempita da 0,5 ml----2件: 62, 66
98Pozelimab1件: Pozelimab1件: D11477 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 11, 62
99RA101495----1件: 62
100RA101495 sodium----1件: 62
101Radiation: total-body irradiation----9件: 28, 51, 60, 62, 65, 96, 283, 284, 285
102RAVULIZUMAB1件: Ravulizumab1件: D11054 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬7件: 2, 11, 13, 50, 62, 66, 109
103Reduced Intensity Preparative Regimen----3件: 62, 65, 284
104Reduced Toxicity Ablative Regimen----3件: 62, 65, 284
105REGN3918----2件: 11, 62
106RO7112689----1件: 62
107RO7112689/F01----1件: 62
108RO7112689/F03-01----2件: 62, 109
109RO7112689/F03-03----1件: 62
110RO7112689/F03-10----2件: 62, 109
111RVA576----3件: 62, 109, 162
112RVA576 (COVERSIN)1件: Nomacopan1件: D11473 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬2件: 62, 109
113Sargramostim1件: Sargramostim1件: D05803 1件: CSF2RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285
114SB12 (proposed eculizumab biosimilar)1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
115Sirolimus1件: Sirolimus1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬36件: 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331
116Solaris----2件: 62, 109
117SOLIRIS1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬7件: 11, 13, 14, 61, 62, 109, 222
118Soliris (eculizumab)1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
119SOLIRIS - 300 MG CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO 1 FLACONCINO (VETRO) 30 ML (10 MG/ML)1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 13, 62, 109
120Soliris 3001件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
121Soliris 300 mg concentrate for solution for infusion1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
122Soliris 300mg/30ml1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
123Soliris®1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
124SOLIRIS® (eculizumab) injection, for intravenous use1件: Eculizumab1件: D03940 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
125Stem Cell Transplantation----13件: 13, 19, 20, 46, 51, 60, 62, 65, 90, 125, 164, 234, 326
126Sterile Normal Saline (0.9% NaCl)----3件: 62, 234, 254
127Sucrose1件: Sucrose1件: D00025 --3件: 62, 96, 97
128Synthetic 15-amino-acid macrocyclic peptide----1件: 62
129Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24----1件: 62
130Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24 palmitoylated linker----1件: 62
131Synthetic 15-amino-acid macrocyclic peptide acylated with a polyethyleneglycol palmitoylated linker----1件: 62
132Systematic chemotherapy and antibodies----1件: 62
133Systemic chemotherapy and antibodies----2件: 62, 326
134Tacrolimus1件: Tacrolimus2件: D00107 ,
D08556
5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
135TREOSULFAN1件: Treosulfan1件: D07253 --6件: 13, 19, 62, 65, 283, 286
136Tretinoin1件: Tretinoin1件: D00094 3件: PML,
RARA,
RARB 💬
12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬3件: 2, 62, 75
137Ultomiris1件: Ravulizumab1件: D11054 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬6件: 2, 11, 13, 50, 62, 66
138ULTOMIRIS - 300 MG - CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - FLACONCINO (VETRO) 3 ML (100 MG / ML) - 1 FLACONCINO1件: Ravulizumab1件: D11054 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
139Ultomiris 300mg/30ml1件: Ravulizumab1件: D11054 1件: C5 💬10件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 62
140VACCINO CONTRO IL MEMINGOCOCCO DI GRUPPO B----3件: 61, 62, 66
141VACCINO HAEMOPHILUS INFLUENZAE B CONIUGATO CON TOSSOIDETETANICO----2件: 61, 62
142VACCINO PNEUMOCOCCICO----2件: 62, 66
143VACCINO POLISACCARIDICO ANTI-MENINGOCOCCICO (A.C.Y E W-135)----3件: 61, 62, 66
144VARI----2件: 62, 274
145Zilucoplan1件: Zilucoplan---3件: 2, 11, 62
146Zilucoplan (RA101495)1件: Zilucoplan---2件: 11, 62
147 LNP023 HYDROCHLORIDE SALT----5件: 61, 62, 66, 109, 222