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Target Gene/Pathway
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Showing 1 to 6 of 6 descriptions
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薬物名(臨床試験情報から抽出)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Caffeine
1件:
Caffeine
Caffeine
2件:
D00528
D00528
(Name:
Caffeine
)
,
D01453
(Name:
Caffeine
hydrate)
11件:
ADORA1
ADORA1
,
ADORA2A
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
,
PDE5A
💬
22件:
Alcoholism
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Glucagon signaling pathway
,
Insulin signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Olfactory transduction
,
Parathyroid hormone synthesis, secretion and action
,
Parkinson disease
,
Progesterone-mediated oocyte maturation
,
Purine metabolism
,
Rap1 signaling pathway
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Sphingolipid signaling pathway
,
Taste transduction
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
22件:
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pa
...
9件:
2
2
,
6
,
13
,
21
,
46
,
78
,
96
,
97
,
265
2
Caffeine
100 mg
1件:
Caffeine
Caffeine
2件:
D00528
D00528
(Name:
Caffeine
)
,
D01453
(Name:
Caffeine
hydrate)
11件:
ADORA1
ADORA1
,
ADORA2A
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
,
PDE5A
💬
22件:
Alcoholism
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Glucagon signaling pathway
,
Insulin signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Olfactory transduction
,
Parathyroid hormone synthesis, secretion and action
,
Parkinson disease
,
Progesterone-mediated oocyte maturation
,
Purine metabolism
,
Rap1 signaling pathway
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Sphingolipid signaling pathway
,
Taste transduction
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
22件:
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pa
...
2件:
96
96
,
97
3
Caffeine
100-200 mg BID
1件:
Caffeine
Caffeine
2件:
D00528
D00528
(Name:
Caffeine
)
,
D01453
(Name:
Caffeine
hydrate)
11件:
ADORA1
ADORA1
,
ADORA2A
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
,
PDE5A
💬
22件:
Alcoholism
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Glucagon signaling pathway
,
Insulin signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Olfactory transduction
,
Parathyroid hormone synthesis, secretion and action
,
Parkinson disease
,
Progesterone-mediated oocyte maturation
,
Purine metabolism
,
Rap1 signaling pathway
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Sphingolipid signaling pathway
,
Taste transduction
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
22件:
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pa
...
1件:
6
6
4
Caffeine
alkaloid
1件:
Caffeine
Caffeine
2件:
D00528
D00528
(Name:
Caffeine
)
,
D01453
(Name:
Caffeine
hydrate)
11件:
ADORA1
ADORA1
,
ADORA2A
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
,
PDE5A
💬
22件:
Alcoholism
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Glucagon signaling pathway
,
Insulin signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Olfactory transduction
,
Parathyroid hormone synthesis, secretion and action
,
Parkinson disease
,
Progesterone-mediated oocyte maturation
,
Purine metabolism
,
Rap1 signaling pathway
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Sphingolipid signaling pathway
,
Taste transduction
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
22件:
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pa
...
1件:
6
6
5
Dextromethorphan and
Caffeine
2件:
Caffeine
Caffeine
,
Dextromethorphan
5件:
D00528
D00528
(Name:
Caffeine
)
,
D00848
,
D01453
(Name:
Caffeine
hydrate)
,
D03742
,
D03744
17件:
ADORA1
ADORA1
,
ADORA2A
,
GRIN1
,
GRIN2A
,
GRIN2B
,
GRIN2C
,
GRIN2D
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
,
PDE5A
,
SIGMAR1
💬
17件:
ADORA1
,
ADORA2A
,
GRIN1
,
GRIN2A
,
GRIN2B
,
GRIN2C
,
GRIN2D
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4
...
37件:
Alcoholism
Alcoholism
,
Aldosterone synthesis and secretion
,
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Circadian entrainment
,
Cocaine addiction
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Huntington disease
,
Insulin signaling pathway
,
Long-term potentiation
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Olfactory transduction
,
Parathyroid hormone synthesis, secretion and action
,
Parkinson disease
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Progesterone-mediated oocyte maturation
,
Purine metabolism
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Sphingolipid signaling pathway
,
Spinocerebellar ataxia
,
Systemic lupus erythematosus
,
Taste transduction
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
37件:
Alcoholism
,
Aldosterone synthesis and secretion
,
Alzheimer disease
,
Amphetamine addiction
,
Amyo
...
1件:
78
78
6
Other:
Caffeine
1件:
Caffeine
Caffeine
2件:
D00528
D00528
(Name:
Caffeine
)
,
D01453
(Name:
Caffeine
hydrate)
11件:
ADORA1
ADORA1
,
ADORA2A
,
PDE1B
,
PDE2A
,
PDE3A
,
PDE3B
,
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
,
PDE5A
💬
22件:
Alcoholism
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Glucagon signaling pathway
,
Insulin signaling pathway
,
Metabolic pathways
,
Morphine addiction
,
Neuroactive ligand-receptor interaction
,
Olfactory transduction
,
Parathyroid hormone synthesis, secretion and action
,
Parkinson disease
,
Progesterone-mediated oocyte maturation
,
Purine metabolism
,
Rap1 signaling pathway
,
Regulation of lipolysis in adipocytes
,
Renin secretion
,
Sphingolipid signaling pathway
,
Taste transduction
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
22件:
Alcoholism
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pa
...
1件:
13
13