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Drug
Description in Trials
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Showing 1 to 10 of 36 drugs
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No.
DrugBank
薬物名(臨床試験情報から抽出)
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Abatacept
2件:
ABATACEPT
ABATACEPT
;
ORENCIA
1件:
D03203
D03203
2件:
CD80
CD80
,
CD86
💬
12件:
Allograft rejection
Allograft rejection
,
Autoimmune thyroid disease
,
Cell adhesion molecules
,
Graft-versus-host disease
,
Intestinal immune network for IgA production
,
Kaposi sarcoma-associated herpesvirus infection
,
Rheumatoid arthritis
,
Systemic lupus erythematosus
,
Toll-like receptor signaling pathway
,
Transcriptional misregulation in cancer
,
Type I diabetes mellitus
,
Viral myocarditis
💬
12件:
Allograft rejection
,
Autoimmune thyroid disease
,
Cell adhesion molecules
,
Graft-versus-host dis
...
26件:
11
11
,
13
,
19
,
41
,
44
,
46
,
49
,
50
,
51
,
53
,
55
,
60
,
65
,
84
,
93
,
95
,
96
,
97
,
107
,
160
,
164
,
222
,
271
,
284
,
285
,
300
26件:
11
,
13
,
19
,
41
,
44
,
46
,
49
,
50
,
51
,
53
,
55
,
60
,
65
,
84
,
93
,
95
,
96
,
97
,
107
,
160
,
164
,
222
,
271
...
2
Adalimumab
6件:
Adalimumab
Adalimumab
;
AMGEVITA
;
Hulio
;
Humira
;
Hyrimoz
;
Imraldi
1件:
D02597
D02597
1件:
TNF
TNF
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
18件:
19
19
,
37
,
40
,
41
,
46
,
56
,
84
,
96
,
97
,
107
,
151
,
160
,
164
,
222
,
226
,
269
,
270
,
271
3
Alendronic acid
3件:
Alendronate
Alendronate
;
Alendronate sodium
;
ALENDRONIC ACID
2件:
D00939
D00939
,
D07119
1件:
FDPS
FDPS
💬
4件:
Human T-cell leukemia virus 1 infection
Human T-cell leukemia virus 1 infection
,
Influenza A
,
Metabolic pathways
,
Terpenoid backbone biosynthesis
💬
4件:
Human T-cell leukemia virus 1 infection
,
Influenza A
,
Metabolic pathways
,
Terpenoid backbone bio
...
7件:
19
19
,
41
,
46
,
50
,
271
,
274
,
299
4
Alfacalcidol
2件:
Alfacalcidol
Alfacalcidol
;
One-alpha
1件:
D01518
D01518
1件:
VDR
VDR
💬
5件:
Chemical carcinogenesis - receptor activation
Chemical carcinogenesis - receptor activation
,
Endocrine and other factor-regulated calcium reabsorption
,
Mineral absorption
,
Parathyroid hormone synthesis, secretion and action
,
Tuberculosis
💬
5件:
Chemical carcinogenesis - receptor activation
,
Endocrine and other factor-regulated calcium reab
...
8件:
41
41
,
46
,
49
,
50
,
96
,
107
,
235
,
238
5
Anakinra
2件:
ANAKINRA
ANAKINRA
;
Kineret
1件:
D02934
D02934
2件:
IL1R1
IL1R1
,
IL1R2
💬
15件:
Amoebiasis
Amoebiasis
,
Cytokine-cytokine receptor interaction
,
Fluid shear stress and atherosclerosis
,
Hematopoietic cell lineage
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Inflammatory mediator regulation of TRP channels
,
MAPK signaling pathway
,
NF-kappa B signaling pathway
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Prostate cancer
,
Shigellosis
,
Th17 cell differentiation
,
Transcriptional misregulation in cancer
💬
15件:
Amoebiasis
,
Cytokine-cytokine receptor interaction
,
Fluid shear stress and atherosclerosis
,
Hem
...
19件:
2
2
,
13
,
15
,
19
,
28
,
37
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
86
,
97
,
106
,
107
,
266
,
299
6
Baricitinib
2件:
BARICITINIB
BARICITINIB
;
OLUMIANT
1件:
D10308
D10308
2件:
JAK1
JAK1
,
JAK2
💬
35件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
Chemical carcinogenesis - receptor activation
,
Chemokine signaling pathway
,
Cholinergic synapse
,
Coronavirus disease - COVID-19
,
EGFR tyrosine kinase inhibitor resistance
,
Epstein-Barr virus infection
,
Growth hormone synthesis, secretion and action
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Influenza A
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Lipid and atherosclerosis
,
Measles
,
NOD-like receptor signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Pathways in cancer
,
Prolactin signaling pathway
,
Signaling pathways regulating pluripotency of stem cells
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Toxoplasmosis
,
Tuberculosis
,
Viral carcinogenesis
💬
35件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
Chemical
...
13件:
41
41
,
46
,
49
,
50
,
51
,
53
,
93
,
107
,
162
,
265
,
268
,
269
,
325
7
Bosentan
2件:
BOSENTAN
BOSENTAN
;
TRACLEER
2件:
D01227
D01227
,
D07538
2件:
EDNRA
EDNRA
,
EDNRB
💬
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
11件:
13
13
,
41
,
47
,
51
,
84
,
85
,
86
,
88
,
210
,
211
,
212
8
Cyclophosphamide
6件:
Ciclofosfamida
Ciclofosfamida
;
Ciclofosfamide
;
Cyclophosphamid
;
Cyclophosphamide
;
Cyclophosphamidum
;
Cytoxan
2件:
D00287
D00287
,
D07760
-
-
45件:
11
11
,
13
,
14
,
16
,
19
,
20
,
26
,
28
,
35
,
36
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
52
,
56
,
60
,
62
,
65
,
66
,
84
,
85
,
93
,
96
,
162
,
164
,
172
,
205
,
222
,
224
,
256
,
265
,
274
,
283
,
284
,
285
,
288
,
326
,
331
45件:
11
,
13
,
14
,
16
,
19
,
20
,
26
,
28
,
35
,
36
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
52
,
56
,
60
,
62
, ...
9
Cyclosporine
10件:
CICLOSPORIN
CICLOSPORIN
;
Ciclosporina
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine A
;
Ikervis
;
NEORAL
;
Restasis
10件:
CICLOSPORIN
;
Ciclosporina
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine
...
1件:
D00184
D00184
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
44件:
11
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
,
65
,
90
,
93
,
95
,
97
,
107
,
113
,
162
,
164
,
222
,
226
,
228
,
234
,
269
,
274
,
283
,
284
,
285
,
302
,
326
44件:
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
, ...
10
Dotatate
2件:
DOTA-TATE
DOTA-TATE
;
Dotatate
-
-
-
4件:
41
41
,
75
,
84
,
238