Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Albendazole 2件: Albendazole; Eskazole1件: D00134 --12件: 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
2 Apomorphine 3件: APOKYN; Apomorfina; Apomorphine2件: D02004 ,
D07460 		2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
3 Botulinum toxin type A 8件: Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬13件: 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
4 Creatine 1件: Creatine---16件: 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
5 Davunetide 1件: Davunetide1件: D09401 --3件: 5, 7, 127
6 Donepezil 3件: ARICEPT; Donepezil; Donepezil hydrochloride2件: D00670 ,
D07869 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
7 Droxidopa 4件: DOPS; Droxidopa; L-DOPS; Northera1件: D01277 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
8 Emeramide 1件: Emeramide---2件: 5, 17
9 Fasudil 1件: Fasudil1件: D07941 2件: ROCK1,
ROCK2 💬		23件: Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, MicroRNAs in cancer, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Proteoglycans in cancer, Regulation of actin cytoskeleton, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, TGF-beta signaling pathway, Tight junction, Vascular smooth muscle contraction, Wnt signaling pathway, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 2, 5, 7, 51
10 Flortaucipir 1件: Flortaucipir1件: D11210 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127
11 Fludeoxyglucose (18F) 3件: 18F-FDG; Fludeoxyglucose; Fludeoxyglucose F 18---14件: 5, 6, 7, 8, 13, 34, 41, 46, 53, 84, 85, 96, 127, 300
12 Flutemetamol 1件: Flutemetamol---5件: 5, 6, 7, 17, 127
13 Flutemetamol (18F) 3件: Flutemetamol; Flutemetamol F18; Vizamyl---5件: 5, 6, 7, 17, 127
14 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
15 Gosuranemab 1件: BMS-9861681件: D11293 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 5
16 Hydrogen 2件: Dihydrogen; Hydrogen---8件: 5, 6, 13, 17, 65, 83, 97, 226
17 Hydroxide ion 2件: Example; Hydroxide---6件: 5, 11, 46, 96, 97, 284
18 Ioflupane I-123 3件: DaTscan; Ioflupane; Ioflupane I 123---4件: 2, 5, 6, 17
19 Leucine 2件: L-leucine; Leucine1件: D00030 --11件: 5, 6, 7, 19, 65, 96, 97, 127, 283, 284, 299
20 Levocarnitine 4件: Carnitine; L-Carnitine; Levocarnitine; Xyzal3件: D02030 ,
D02176 ,
D04713 		--11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
21 Linoleic acid 1件: Linoleic acid---8件: 2, 5, 6, 13, 75, 76, 222, 299
22 Lipoic acid 3件: Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid2件: D00048 ,
D00086 		--5件: 2, 5, 13, 14, 20
23 Lithium citrate 2件: Lithium; LITHIUM CITRATE1件: D04749 --5件: 2, 5, 6, 7, 8
24 Masitinib 1件: Masitinib1件: D10229 1件: KIT 💬11件: Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬6件: 2, 5, 6, 13, 46, 96
25 Nicotinamide 4件: Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
26 Nitrogen 1件: Nitrogen1件: D00083 --6件: 5, 6, 17, 171, 211, 299
27 Raclopride 1件: Raclopride---4件: 5, 6, 7, 17
28 Rasagiline 4件: Azilect; Rasagilina; Rasagiline; Rasagiline mesylate3件: D02562 ,
D08469 ,
D10829 		1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 2, 5, 6, 13, 17, 58, 66
29 Riluzole 2件: RILUTEK; Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
30 Rivastigmine 3件: EXELON; Rivastigmine; Rivastigmine Transdermal System2件: D02558 ,
D03822 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬3件: 5, 6, 13
31 Salsalate 1件: Salsalate1件: D00428 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
32 Suvorexant 1件: Suvorexant1件: D10082 2件: HCRTR1,
HCRTR2 💬		1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13
33 Tideglusib 1件: Tideglusib---2件: 5, 113
34 Tolfenamic acid 1件: Tolfenamic Acid1件: D01183 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
35 Trihexyphenidyl 1件: Trihexyphenidyl2件: D00787 ,
D08638 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
36 Ubidecarenone 3件: Coenzyme Q-10; Coenzyme Q10; CoQ101件: D01065 --13件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
37 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
38 Water 9件: AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --23件: 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299
39 Zoledronic acid 4件: ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa4件: D01968 ,
D06378 ,
D06379 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
40 Zolpidem 2件: Zolpidem; Zolpidem Tartrate2件: D00706 ,
D08690 		16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 5, 6, 46