Drug Description in Trials / DrugBank / KEGG DRUG

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No.	DrugBank	薬物名（臨床試験情報から抽出）	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Acetaminophen	5件: Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet	1件: D00217 (Name: Acetaminophen)	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...	18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2	Acetylsalicylic acid (Synonym: Acetaminophen 250mg Aspirin 250mg Caffeine 65mg)	2件: ACETYLSALICYLIC ACID; Aspirin	1件: D00109	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...	15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
3	Caffeine (Synonym: Acetaminophen 325 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)	1件: Caffeine	2件: D00528 , D01453	11件: ADORA1, ADORA2A, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬	22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pa ...	9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
4	Dextromethorphan (Synonym: Acetaminophen Dextromethorphan HBr Guaifenesin Phenylephrine HCl)	4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta	3件: D00848 , D03742 , D03744	6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬	20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
5	Diphenhydramine (Synonym: Basic Care Acetaminophen PM)	2件: Diphenhydramine; Diphenhydramine hydrochloride	6件: D00300 , D00669 , D02419 , D03285 , D03360 , D03854	1件: HRH1 💬	3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand- ...	10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
6	Ibuprofen (Synonym: Hydrocodone Bitartrate and Acetaminophen)	2件: Ibuprofen; IBUPROFEN 200MG	4件: D00126 , D01122 , D04490 , D06606	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...	7件: 13, 46, 65, 107, 113, 271, 299
7	Oxycodone (Synonym: Ntp-oxycodone Acetaminophen)	3件: Oxycodone; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen	3件: D03783 , D05312 , D05462	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingo ...	7件: 6, 13, 46, 70, 226, 231, 298
8	Phenylephrine (Synonym: Cough Syrup DM Decongestant and Expectorant With Acetaminophen)	1件: Phenylephrine	2件: D00511 , D08365	3件: ADRA1A, ADRA1B, ADRA1D 💬	7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuro ...	1件: 22
9	Pseudoephedrine (Synonym: Acetaminophen/dextromethorphan/pseudoephedrine)	1件: Pseudoephedrine	4件: D00485 , D05648 , D05649 , D08449	9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chem ...	1件: 17
10	Tramadol (Synonym: Tramadol / Acetaminophen)	2件: Tramadol; Ultracet	2件: D01355 , D08623	1件: OPRM1 💬	3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬	5件: 46, 70, 78, 226, 271

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