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Target Gene/Pathway
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Showing 1 to 10 of 114 drugs
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No.
KEGG DRUG
DrugBank
薬物名(臨床試験情報から抽出)
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Nitric oxide
1件:
Nitric Oxide
Nitric Oxide
3件:
INOmax
INOmax
;
Nitric Oxide
;
Nitrosyl
;
-
-
16件:
6
6
,
13
,
46
,
58
,
85
,
86
,
96
,
97
,
98
,
210
,
222
,
226
,
251
,
294
,
299
,
321
2
Tacrolimus
1件:
Tacrolimus
Tacrolimus
2件:
Prograf
Prograf
;
Tacrolimus
;
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
34件:
2
2
,
6
,
11
,
13
,
36
,
46
,
49
,
50
,
51
,
53
,
56
,
60
,
61
,
62
,
65
,
66
,
85
,
95
,
96
,
97
,
113
,
151
,
158
,
164
,
222
,
224
,
226
,
227
,
228
,
283
,
284
,
285
,
286
,
299
34件:
2
,
6
,
11
,
13
,
36
,
46
,
49
,
50
,
51
,
53
,
56
,
60
,
61
,
62
,
65
,
66
,
85
,
95
,
96
,
97
,
113
,
151
,
158
,
16
...
3
Corticotropin
1件:
Corticotropin
Corticotropin
5件:
ACTH
ACTH
;
ACTHAR
;
Adrenocorticotropic hormone
;
Corticotrophin
;
Corticotropin
;
1件:
MC2R
MC2R
💬
5件:
Aldosterone synthesis and secretion
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
,
Neuroactive ligand-receptor interaction
,
cAMP signaling pathway
💬
5件:
Aldosterone synthesis and secretion
,
Cortisol synthesis and secretion
,
Cushing syndrome
,
Neuroac
...
15件:
2
2
,
13
,
14
,
46
,
49
,
50
,
66
,
75
,
78
,
81
,
84
,
145
,
193
,
205
,
222
4
Angiotensin II
1件:
Angiotensin II
Angiotensin II
2件:
Angiotensin
Angiotensin
;
Angiotensin II
;
2件:
AGTR1
AGTR1
,
AGTR2
💬
16件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Apelin signaling pathway
,
Calcium signaling pathway
,
Coronavirus disease - COVID-19
,
Cortisol synthesis and secretion
,
Cushing syndrome
,
Diabetic cardiomyopathy
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Phospholipase D signaling pathway
,
Renin secretion
,
Renin-angiotensin system
,
Vascular smooth muscle contraction
,
cGMP-PKG signaling pathway
💬
16件:
AGE-RAGE signaling pathway in diabetic complications
,
Adrenergic signaling in cardiomyocytes
,
A
...
7件:
17
17
,
19
,
46
,
66
,
86
,
222
,
224
5
Cyclosporine
1件:
Cyclosporine
Cyclosporine
10件:
CICLOSPORIN
CICLOSPORIN
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine A
;
Ikervis
;
Neoral
;
Restasis
;
10件:
CICLOSPORIN
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine
...
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
44件:
11
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
,
65
,
90
,
93
,
95
,
97
,
107
,
113
,
162
,
164
,
222
,
226
,
228
,
234
,
269
,
274
,
283
,
284
,
285
,
302
,
326
44件:
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
, ...
6
Acetaminophen
1件:
Acetaminophen
Acetaminophen
5件:
Acetaminophen
Acetaminophen
;
Oxycodone/Acetaminophen
;
Paracetamol
;
Tylenol
;
Ultracet
;
2件:
PTGS1
PTGS1
,
PTGS2
💬
23件:
Alzheimer disease
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemical carcinogenesis - DNA adducts
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Platelet activation
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
VEGF signaling pathway
💬
23件:
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemi
...
18件:
3
3
,
6
,
11
,
13
,
34
,
35
,
46
,
49
,
51
,
70
,
86
,
96
,
222
,
231
,
256
,
271
,
300
,
337
7
Amoxicillin
1件:
Amoxicillin
Amoxicillin
4件:
Amoxicilina
Amoxicilina
;
AMOXICILLIN
;
Amoxycillin
;
Augmentin
;
-
-
9件:
6
6
,
19
,
46
,
63
,
84
,
96
,
97
,
222
,
299
8
Cefadroxil
1件:
Cefadroxil
Cefadroxil
0件:
-
-
2件:
222
222
,
240
9
Cefixime
1件:
Atorvastatin
Atorvastatin
3件:
Atorvastatin
Atorvastatin
;
Atorvastatin Calcium
;
Lipitor
;
-
-
18件:
13
13
,
46
,
49
,
51
,
58
,
63
,
79
,
84
,
88
,
93
,
96
,
97
,
160
,
222
,
225
,
265
,
271
,
299
10
Chlorambucil
1件:
Chlorambucil
Chlorambucil
1件:
Chlorambucil
Chlorambucil
;
-
-
1件:
222
222