Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	IL1A	21件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, Necroptosis, Cellular senescenc ...	D06635	Rilonacept	4件: 51, 106, 107, 266
2	IL1B	44件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa ...	D06635	Rilonacept	4件: 51, 106, 107, 266
3	IL1B	44件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa ...	D09315	Canakinumab	10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
4	IL1R1	13件: MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, O ...	D02934	Anakinra	19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
5	IL1R2	7件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Amoebiasis, Human T-cell leu ...	D02934	Anakinra	19件: 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299

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