Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ADRB1 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy D07660 Celiprolol 1件: 168
2 AGTR1 16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Apelin signaling pathway, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Coronavirus disease - COVID-19, Pathways in cancer, Diabetic cardiomyopathy D00523 Irbesartan 4件: 66, 167, 168, 222
3 GHR 5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Growth hormone synthesis, secretion and action D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
4 GHR 5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Growth hormone synthesis, secretion and action D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
5 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Oocyte meiosis, Autophagy - animal, Endocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Focal adhesion, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Long-term depression, Ovarian steroidogenesis, Progesterone-mediated oocyte maturation, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, Glioma, Prostate cancer, Melanoma, Breast cancer, Hepatocellular carcinoma D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
6 IGF1R 29件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Oocyte meiosis, Autophagy - animal, Endocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Focal adhesion, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Long-term depression, Ovarian steroidogenesis, Progesterone-mediated oocyte maturation, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, Glioma, Prostate cancer, Melanoma, Breast cancer, Hepatocellular carcinoma D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
7 SCN1A 1件: Dopaminergic synapse D00358 Lidocaine 4件: 168, 226, 231, 256
8 SCN1A 1件: Dopaminergic synapse D01450 Bupivacaine 3件: 168, 226, 298
9 SCN1A 1件: Dopaminergic synapse D02086 Lidocaine 4件: 168, 226, 231, 256
10 SCN1A 1件: Dopaminergic synapse D07552 Bupivacaine 3件: 168, 226, 298
11 SCN1A 1件: Dopaminergic synapse D08127 Lidocaine 4件: 168, 226, 231, 256
12 SCN2A 1件: Taste transduction D00358 Lidocaine 4件: 168, 226, 231, 256
13 SCN2A 1件: Taste transduction D01450 Bupivacaine 3件: 168, 226, 298
14 SCN2A 1件: Taste transduction D02086 Lidocaine 4件: 168, 226, 231, 256
15 SCN2A 1件: Taste transduction D07552 Bupivacaine 3件: 168, 226, 298
16 SCN2A 1件: Taste transduction D08127 Lidocaine 4件: 168, 226, 231, 256
17 SCN3A 1件: Taste transduction D00358 Lidocaine 4件: 168, 226, 231, 256
18 SCN3A 1件: Taste transduction D01450 Bupivacaine 3件: 168, 226, 298
19 SCN3A 1件: Taste transduction D02086 Lidocaine 4件: 168, 226, 231, 256
20 SCN3A 1件: Taste transduction D07552 Bupivacaine 3件: 168, 226, 298
21 SCN3A 1件: Taste transduction D08127 Lidocaine 4件: 168, 226, 231, 256
22 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00358 Lidocaine 4件: 168, 226, 231, 256
23 SCN5A 1件: Adrenergic signaling in cardiomyocytes D01450 Bupivacaine 3件: 168, 226, 298
24 SCN5A 1件: Adrenergic signaling in cardiomyocytes D02086 Lidocaine 4件: 168, 226, 231, 256
25 SCN5A 1件: Adrenergic signaling in cardiomyocytes D07552 Bupivacaine 3件: 168, 226, 298
26 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08127 Lidocaine 4件: 168, 226, 231, 256
27 SCN9A 1件: Taste transduction D00358 Lidocaine 4件: 168, 226, 231, 256
28 SCN9A 1件: Taste transduction D01450 Bupivacaine 3件: 168, 226, 298
29 SCN9A 1件: Taste transduction D02086 Lidocaine 4件: 168, 226, 231, 256
30 SCN9A 1件: Taste transduction D07552 Bupivacaine 3件: 168, 226, 298
31 SCN9A 1件: Taste transduction D08127 Lidocaine 4件: 168, 226, 231, 256