Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D00848	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
3	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03744	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
4	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D00528	Caffeine	9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
5	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D01453	Caffeine	9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
6	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D00528	Caffeine	9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
7	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D01453	Caffeine	9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
8	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
9	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D01205	Dexmedetomidine	13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
10	ADRA2B	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	13件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280

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