Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CD52	-	D02802	Alemtuzumab	5件: 234, 283, 284, 285, 326
2	POLA2	1件: DNA replication	D03546	Clofarabine	2件: 234, 326
3	IMPDH1	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D00752	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
4	IMPDH1	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D05094	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
5	IMPDH1	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D05095	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
6	IMPDH1	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D05096	Mycophenolic acid	36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, ...
7	IMPDH2	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D00752	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
8	IMPDH2	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D05094	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
9	IMPDH2	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D05095	Mycophenolate mofetil	34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, ...
10	IMPDH2	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D05096	Mycophenolic acid	36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, ...

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