Target Gene/Pathway Pathway / Gene


Search results


No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 DRD1 10件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism D00633 Dopamine 4件: 6, 7, 74, 299
2 DRD1 10件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism D07870 Dopamine 4件: 6, 7, 74, 299
3 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D00633 Dopamine 4件: 6, 7, 74, 299
4 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D00780 Bromocriptine 2件: 6, 74
5 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D00784 Ropinirole 4件: 2, 6, 74, 309
6 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D00987 Cabergoline 3件: 6, 74, 75
7 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D03165 Bromocriptine 2件: 6, 74
8 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D07870 Dopamine 4件: 6, 7, 74, 299
9 DRD2 8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism D08489 Ropinirole 4件: 2, 6, 74, 309
10 DRD3 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D00633 Dopamine 4件: 6, 7, 74, 299
11 DRD3 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D00784 Ropinirole 4件: 2, 6, 74, 309
12 DRD3 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D07870 Dopamine 4件: 6, 7, 74, 299
13 DRD3 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D08489 Ropinirole 4件: 2, 6, 74, 309
14 DRD4 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D00633 Dopamine 4件: 6, 7, 74, 299
15 DRD4 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D00784 Ropinirole 4件: 2, 6, 74, 309
16 DRD4 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D07870 Dopamine 4件: 6, 7, 74, 299
17 DRD4 2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse D08489 Ropinirole 4件: 2, 6, 74, 309
18 DRD5 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse D00633 Dopamine 4件: 6, 7, 74, 299
19 DRD5 4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse D07870 Dopamine 4件: 6, 7, 74, 299
20 EGFR 48件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D04024 Lapatinib 3件: 34, 74, 75
21 EGFR 48件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer D08108 Lapatinib 3件: 34, 74, 75
22 ERBB2 22件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Platinum drug resistance, MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer D04024 Lapatinib 3件: 34, 74, 75
23 ERBB2 22件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Platinum drug resistance, MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer D08108 Lapatinib 3件: 34, 74, 75
24 ESR1 9件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer D00962 Clomifene 1件: 74
25 ESR1 9件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Endocrine and other factor-regulated calcium reabsorption, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Breast cancer D07726 Clomifene 1件: 74
26 ESR2 7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer D00962 Clomifene 1件: 74
27 ESR2 7件: Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer D07726 Clomifene 1件: 74
28 GHR 5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Growth hormone synthesis, secretion and action D02691 Somatotropin 23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
29 NR3C1 1件: Neuroactive ligand-receptor interaction D00292 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
30 NR3C1 1件: Neuroactive ligand-receptor interaction D00975 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
31 NR3C1 1件: Neuroactive ligand-receptor interaction D01510 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
32 NR3C1 1件: Neuroactive ligand-receptor interaction D01615 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
33 NR3C1 1件: Neuroactive ligand-receptor interaction D01632 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
34 NR3C1 1件: Neuroactive ligand-receptor interaction D01948 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
35 NR3C1 1件: Neuroactive ligand-receptor interaction D02174 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
36 NR3C1 1件: Neuroactive ligand-receptor interaction D02591 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
37 NR3C1 1件: Neuroactive ligand-receptor interaction D02592 Dexamethasone 14件: 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
38 PRL 5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Prolactin signaling pathway D00780 Bromocriptine 2件: 6, 74
39 PRL 5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Prolactin signaling pathway D00987 Cabergoline 3件: 6, 74, 75
40 PRL 5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Prolactin signaling pathway D03165 Bromocriptine 2件: 6, 74
41 SSTR1 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
42 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D10147 Pasireotide 3件: 67, 74, 75
43 SSTR3 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
44 SSTR5 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75