Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CCR5	9件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine rec ...	D09878	Cenicriviroc	1件: 94
2	EGFR	48件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D04023	Erlotinib	1件: 94
3	EGFR	48件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, MAPK signaling pathway, ErbB s ...	D07907	Erlotinib	1件: 94
4	NR3C1	1件: Neuroactive ligand-receptor interaction	D00246	Budesonide	7件: 94, 95, 96, 97, 98, 228, 299
5	HMGCR	4件: Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion	D00434	Simvastatin	21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
6	IMPDH1	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D01392	Mizoribine	8件: 46, 49, 51, 53, 66, 94, 222, 224
7	IMPDH2	3件: Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways	D01392	Mizoribine	8件: 46, 49, 51, 53, 66, 94, 222, 224
8	ITGA4	14件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, ...	D08083	Vedolizumab	3件: 94, 96, 97
9	ITGB7	11件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, ...	D08083	Vedolizumab	3件: 94, 96, 97
10	PML	7件: Ubiquitin mediated proteolysis, Endocytosis, Influenza A, Herpes simplex virus 1 infection, Path ...	D00094	Tretinoin	6件: 2, 62, 63, 75, 94, 231

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