Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D00529	Montelukast	8件: 6, 13, 46, 61, 63, 85, 98, 228
2	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D08229	Montelukast	8件: 6, 13, 46, 61, 63, 85, 98, 228
3	CHRM1	8件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D01000	Bethanechol	1件: 98
4	CHRM2	6件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K ...	D01000	Bethanechol	1件: 98
5	CHRM3	11件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste ...	D01000	Bethanechol	1件: 98
6	CHRM4	3件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton	D01000	Bethanechol	1件: 98
7	CHRM5	6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulat ...	D01000	Bethanechol	1件: 98
8	AGTR1	16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00357	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
9	AGTR1	16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D08146	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
10	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D10930	Etrasimod	3件: 96, 97, 98

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