Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CDK4	25件: Endocrine resistance, Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular s ...	D10688	Abemaciclib	1件: 34
2	CDK6	22件: Cell cycle, p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syn ...	D10688	Abemaciclib	1件: 34
3	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D01441	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
4	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D03252	Bosutinib	2件: 2, 67
5	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D03658	Dasatinib	2件: 51, 85
6	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D06414	Dasatinib	2件: 51, 85
7	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D08066	Imatinib	12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
8	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D08953	Nilotinib	5件: 6, 8, 34, 51, 86
9	ABL1	10件: ErbB signaling pathway, Ras signaling pathway, Cell cycle, Neurotrophin signaling pathway, Path ...	D09664	Saracatinib	3件: 6, 89, 272
10	HDAC1	13件: Cell cycle, Longevity regulating pathway - multiple species, Notch signaling pathway, Neutrophi ...	D06320	Vorinostat	3件: 19, 75, 96

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