Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 MASP2 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11531 Narsoplimab 4件: 64, 66, 109, 222
2 CFD 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11641 Danicopan 2件: 62, 222
3 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D06410 Thrombomodulin Alfa 1件: 85
4 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D07144 Dabigatran etexilate 1件: 51
5 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D09707 Dabigatran 4件: 51, 85, 91, 124
6 F8 1件: Complement and coagulation cascades D00291 Desmopressin 6件: 6, 64, 72, 75, 225, 288
7 F8 1件: Complement and coagulation cascades D02235 Desmopressin 6件: 6, 64, 72, 75, 225, 288
8 F9 1件: Complement and coagulation cascades D10821 Emicizumab 1件: 288
9 F10 1件: Complement and coagulation cascades D03213 Apixaban 3件: 96, 97, 222
10 F10 1件: Complement and coagulation cascades D07086 Rivaroxaban 5件: 46, 49, 75, 91, 210
11 F10 1件: Complement and coagulation cascades D09710 Edoxaban 2件: 46, 88
12 F10 1件: Complement and coagulation cascades D10821 Emicizumab 1件: 288
13 SERPIND1 1件: Complement and coagulation cascades D08547 Sulodexide 4件: 13, 51, 271, 288
14 KLKB1 1件: Complement and coagulation cascades D10845 Conestat alfa 1件: 61
15 SERPINC1 1件: Complement and coagulation cascades D03674 Enoxaparin 1件: 46
16 SERPINC1 1件: Complement and coagulation cascades D07510 Heparin 12件: 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317
17 SERPINC1 1件: Complement and coagulation cascades D07510 Enoxaparin 1件: 46
18 SERPINC1 1件: Complement and coagulation cascades D07510 Parnaparin 1件: 97
19 SERPINC1 1件: Complement and coagulation cascades D08547 Sulodexide 4件: 13, 51, 271, 288
20 PLG 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D00160 Aminocaproic acid 1件: 70
21 PLG 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A D01136 Tranexamic acid 6件: 46, 70, 215, 227, 288, 299
22 CFB 3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D12251 Iptacopan 5件: 61, 62, 66, 109, 222
23 C1R 6件: Phagosome, Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
24 C1S 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D10845 Conestat alfa 1件: 61
25 C1S 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11530 Sutimlimab 1件: 61
26 C3 15件: Neuroactive ligand-receptor interaction, Phagosome, Complement and coagulation cascades, Neutrophil extracellular trap formation, Shigellosis, Pertussis, Legionellosis, Leishmaniasis, Staphylococcus aureus infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Viral carcinogenesis, Systemic lupus erythematosus D11613 Pegcetacoplan 3件: 2, 62, 222
27 C5 9件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D03940 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222
28 C5 9件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11054 Ravulizumab 7件: 2, 11, 13, 50, 62, 66, 109
29 C5 9件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11473 Nomacopan 3件: 62, 109, 162
30 C5 9件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11477 Pozelimab 2件: 11, 62
31 C5 9件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11696 Crovalimab 2件: 62, 109
32 C5 9件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D11838 Vilobelimab 3件: 43, 44, 269
33 C5AR1 5件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Staphylococcus aureus infection, Coronavirus disease - COVID-19 D11093 Avacopan 3件: 43, 44, 222
34 VWF 8件: PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Complement and coagulation cascades, Platelet activation, Neutrophil extracellular trap formation, Human papillomavirus infection, Coronavirus disease - COVID-19 D11160 Caplacizumab 1件: 64