Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MAPK14	48件: MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling ...	D09639	Losmapimod	2件: 113, 222
2	MAPK14	48件: MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling ...	D10959	Neflamapimod	1件: 8
3	CSF2	12件: JAK-STAT signaling pathway, Hematopoietic cell lineage, Natural killer cell mediated cytotoxici ...	D11343	Otilimab	2件: 46, 256
4	FCER1A	3件: Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...	D05251	Omalizumab	7件: 46, 53, 65, 98, 162, 226, 299
5	ALOX5	5件: Metabolic pathways, Fc epsilon RI signaling pathway, Serotonergic synapse, Ovarian steroidogenes ...	D00414	Zileuton	3件: 85, 160, 164
6	ALOX5	5件: Metabolic pathways, Fc epsilon RI signaling pathway, Serotonergic synapse, Ovarian steroidogenes ...	D01773	Oxatomide	1件: 113
7	FYN	11件: Sphingolipid signaling pathway, Phospholipase D signaling pathway, Osteoclast differentiation, ...	D03658	Dasatinib	2件: 51, 85
8	FYN	11件: Sphingolipid signaling pathway, Phospholipase D signaling pathway, Osteoclast differentiation, ...	D06414	Dasatinib	2件: 51, 85
9	IL4	12件: PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, IL-17 signa ...	D03117	Binetrakin	1件: 46
10	IL5	9件: JAK-STAT signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Th1 and Th2 cel ...	D04923	Mepolizumab	4件: 44, 45, 98, 162

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