Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CHRM1 1件: Regulation of actin cytoskeleton D00113 Atropine 2件: 2, 299
2 CHRM1 1件: Regulation of actin cytoskeleton D00138 Scopolamine 1件: 2
3 CHRM1 1件: Regulation of actin cytoskeleton D00270 Chlorpromazine 1件: 254
4 CHRM1 1件: Regulation of actin cytoskeleton D00397 Tropicamide 3件: 6, 13, 19
5 CHRM1 1件: Regulation of actin cytoskeleton D00465 Oxybutynin 3件: 6, 13, 53
6 CHRM1 1件: Regulation of actin cytoskeleton D00481 Propantheline 1件: 26
7 CHRM1 1件: Regulation of actin cytoskeleton D00722 Oxybutynin 3件: 6, 13, 53
8 CHRM1 1件: Regulation of actin cytoskeleton D00765 Rocuronium 1件: 296
9 CHRM1 1件: Regulation of actin cytoskeleton D00787 Trihexyphenidyl 2件: 5, 6
10 CHRM1 1件: Regulation of actin cytoskeleton D00789 Chlorpromazine 1件: 254
11 CHRM1 1件: Regulation of actin cytoskeleton D01000 Bethanechol 1件: 98
12 CHRM1 1件: Regulation of actin cytoskeleton D01077 Atropine 2件: 2, 299
13 CHRM1 1件: Regulation of actin cytoskeleton D02069 Atropine 2件: 2, 299
14 CHRM1 1件: Regulation of actin cytoskeleton D02212 Ipratropium 2件: 6, 86
15 CHRM1 1件: Regulation of actin cytoskeleton D03011 Atropine 2件: 2, 299
16 CHRM1 1件: Regulation of actin cytoskeleton D03274 Chlorpromazine 1件: 254
17 CHRM1 1件: Regulation of actin cytoskeleton D03814 Atropine 2件: 2, 299
18 CHRM1 1件: Regulation of actin cytoskeleton D04034 Chlorpromazine 1件: 254
19 CHRM1 1件: Regulation of actin cytoskeleton D08441 Propiverine 1件: 226
20 CHRM1 1件: Regulation of actin cytoskeleton D08638 Trihexyphenidyl 2件: 5, 6
21 CHRM1 1件: Regulation of actin cytoskeleton D11383 Blarcamesine 1件: 156
22 CHRM2 1件: Regulation of actin cytoskeleton D00113 Atropine 2件: 2, 299
23 CHRM2 1件: Regulation of actin cytoskeleton D00138 Scopolamine 1件: 2
24 CHRM2 1件: Regulation of actin cytoskeleton D00270 Chlorpromazine 1件: 254
25 CHRM2 1件: Regulation of actin cytoskeleton D00397 Tropicamide 3件: 6, 13, 19
26 CHRM2 1件: Regulation of actin cytoskeleton D00465 Oxybutynin 3件: 6, 13, 53
27 CHRM2 1件: Regulation of actin cytoskeleton D00481 Propantheline 1件: 26
28 CHRM2 1件: Regulation of actin cytoskeleton D00525 Pilocarpine 3件: 6, 53, 299
29 CHRM2 1件: Regulation of actin cytoskeleton D00722 Oxybutynin 3件: 6, 13, 53
30 CHRM2 1件: Regulation of actin cytoskeleton D00765 Rocuronium 1件: 296
31 CHRM2 1件: Regulation of actin cytoskeleton D00787 Trihexyphenidyl 2件: 5, 6
32 CHRM2 1件: Regulation of actin cytoskeleton D00789 Chlorpromazine 1件: 254
33 CHRM2 1件: Regulation of actin cytoskeleton D01000 Bethanechol 1件: 98
34 CHRM2 1件: Regulation of actin cytoskeleton D01077 Atropine 2件: 2, 299
35 CHRM2 1件: Regulation of actin cytoskeleton D02069 Atropine 2件: 2, 299
36 CHRM2 1件: Regulation of actin cytoskeleton D02200 Pilocarpine 3件: 6, 53, 299
37 CHRM2 1件: Regulation of actin cytoskeleton D02212 Ipratropium 2件: 6, 86
38 CHRM2 1件: Regulation of actin cytoskeleton D03011 Atropine 2件: 2, 299
39 CHRM2 1件: Regulation of actin cytoskeleton D03274 Chlorpromazine 1件: 254
40 CHRM2 1件: Regulation of actin cytoskeleton D03814 Atropine 2件: 2, 299
41 CHRM2 1件: Regulation of actin cytoskeleton D04034 Chlorpromazine 1件: 254
42 CHRM2 1件: Regulation of actin cytoskeleton D05478 Pilocarpine 3件: 6, 53, 299
43 CHRM2 1件: Regulation of actin cytoskeleton D07226 Fesoterodine 1件: 6
44 CHRM2 1件: Regulation of actin cytoskeleton D08441 Propiverine 1件: 226
45 CHRM2 1件: Regulation of actin cytoskeleton D08638 Trihexyphenidyl 2件: 5, 6
46 CHRM2 1件: Regulation of actin cytoskeleton D11383 Blarcamesine 1件: 156
47 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00113 Atropine 2件: 2, 299
48 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00138 Scopolamine 1件: 2
49 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00270 Chlorpromazine 1件: 254
50 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00397 Tropicamide 3件: 6, 13, 19
51 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00465 Oxybutynin 3件: 6, 13, 53
52 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00481 Propantheline 1件: 26
53 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00525 Pilocarpine 3件: 6, 53, 299
54 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00646 Tolterodine 2件: 17, 53
55 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00661 Cevimeline 1件: 53
56 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00722 Oxybutynin 3件: 6, 13, 53
57 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00765 Rocuronium 1件: 296
58 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00787 Trihexyphenidyl 2件: 5, 6
59 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D00789 Chlorpromazine 1件: 254
60 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01000 Bethanechol 1件: 98
61 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01077 Atropine 2件: 2, 299
62 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01148 Tolterodine 2件: 17, 53
63 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01269 Solifenacin 3件: 6, 13, 53
64 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D01699 Darifenacin 2件: 6, 13
65 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D02069 Atropine 2件: 2, 299
66 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D02200 Pilocarpine 3件: 6, 53, 299
67 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D02212 Ipratropium 2件: 6, 86
68 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03011 Atropine 2件: 2, 299
69 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03274 Chlorpromazine 1件: 254
70 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03654 Darifenacin 2件: 6, 13
71 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D03814 Atropine 2件: 2, 299
72 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D04034 Chlorpromazine 1件: 254
73 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D05478 Pilocarpine 3件: 6, 53, 299
74 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D07226 Fesoterodine 1件: 6
75 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D07667 Cevimeline 1件: 53
76 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D08441 Propiverine 1件: 226
77 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D08522 Solifenacin 3件: 6, 13, 53
78 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D08638 Trihexyphenidyl 2件: 5, 6
79 CHRM3 3件: Taste transduction, Regulation of actin cytoskeleton, Salivary secretion D11383 Blarcamesine 1件: 156
80 CHRM4 1件: Regulation of actin cytoskeleton D00113 Atropine 2件: 2, 299
81 CHRM4 1件: Regulation of actin cytoskeleton D00138 Scopolamine 1件: 2
82 CHRM4 1件: Regulation of actin cytoskeleton D00270 Chlorpromazine 1件: 254
83 CHRM4 1件: Regulation of actin cytoskeleton D00397 Tropicamide 3件: 6, 13, 19
84 CHRM4 1件: Regulation of actin cytoskeleton D00465 Oxybutynin 3件: 6, 13, 53
85 CHRM4 1件: Regulation of actin cytoskeleton D00481 Propantheline 1件: 26
86 CHRM4 1件: Regulation of actin cytoskeleton D00722 Oxybutynin 3件: 6, 13, 53
87 CHRM4 1件: Regulation of actin cytoskeleton D00765 Rocuronium 1件: 296
88 CHRM4 1件: Regulation of actin cytoskeleton D00787 Trihexyphenidyl 2件: 5, 6
89 CHRM4 1件: Regulation of actin cytoskeleton D00789 Chlorpromazine 1件: 254
90 CHRM4 1件: Regulation of actin cytoskeleton D01000 Bethanechol 1件: 98
91 CHRM4 1件: Regulation of actin cytoskeleton D01077 Atropine 2件: 2, 299
92 CHRM4 1件: Regulation of actin cytoskeleton D02069 Atropine 2件: 2, 299
93 CHRM4 1件: Regulation of actin cytoskeleton D02212 Ipratropium 2件: 6, 86
94 CHRM4 1件: Regulation of actin cytoskeleton D03011 Atropine 2件: 2, 299
95 CHRM4 1件: Regulation of actin cytoskeleton D03274 Chlorpromazine 1件: 254
96 CHRM4 1件: Regulation of actin cytoskeleton D03814 Atropine 2件: 2, 299
97 CHRM4 1件: Regulation of actin cytoskeleton D04034 Chlorpromazine 1件: 254
98 CHRM4 1件: Regulation of actin cytoskeleton D08441 Propiverine 1件: 226
99 CHRM4 1件: Regulation of actin cytoskeleton D08638 Trihexyphenidyl 2件: 5, 6
100 CHRM4 1件: Regulation of actin cytoskeleton D11383 Blarcamesine 1件: 156
101 CHRM5 1件: Regulation of actin cytoskeleton D00113 Atropine 2件: 2, 299
102 CHRM5 1件: Regulation of actin cytoskeleton D00138 Scopolamine 1件: 2
103 CHRM5 1件: Regulation of actin cytoskeleton D00270 Chlorpromazine 1件: 254
104 CHRM5 1件: Regulation of actin cytoskeleton D00397 Tropicamide 3件: 6, 13, 19
105 CHRM5 1件: Regulation of actin cytoskeleton D00465 Oxybutynin 3件: 6, 13, 53
106 CHRM5 1件: Regulation of actin cytoskeleton D00481 Propantheline 1件: 26
107 CHRM5 1件: Regulation of actin cytoskeleton D00722 Oxybutynin 3件: 6, 13, 53
108 CHRM5 1件: Regulation of actin cytoskeleton D00765 Rocuronium 1件: 296
109 CHRM5 1件: Regulation of actin cytoskeleton D00787 Trihexyphenidyl 2件: 5, 6
110 CHRM5 1件: Regulation of actin cytoskeleton D00789 Chlorpromazine 1件: 254
111 CHRM5 1件: Regulation of actin cytoskeleton D01000 Bethanechol 1件: 98
112 CHRM5 1件: Regulation of actin cytoskeleton D01077 Atropine 2件: 2, 299
113 CHRM5 1件: Regulation of actin cytoskeleton D02069 Atropine 2件: 2, 299
114 CHRM5 1件: Regulation of actin cytoskeleton D02212 Ipratropium 2件: 6, 86
115 CHRM5 1件: Regulation of actin cytoskeleton D03011 Atropine 2件: 2, 299
116 CHRM5 1件: Regulation of actin cytoskeleton D03274 Chlorpromazine 1件: 254
117 CHRM5 1件: Regulation of actin cytoskeleton D03814 Atropine 2件: 2, 299
118 CHRM5 1件: Regulation of actin cytoskeleton D04034 Chlorpromazine 1件: 254
119 CHRM5 1件: Regulation of actin cytoskeleton D08441 Propiverine 1件: 226
120 CHRM5 1件: Regulation of actin cytoskeleton D08638 Trihexyphenidyl 2件: 5, 6
121 CHRM5 1件: Regulation of actin cytoskeleton D11383 Blarcamesine 1件: 156
122 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D01977 Gefitinib 1件: 75
123 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D03455 Cetuximab 5件: 34, 51, 86, 89, 331
124 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04023 Erlotinib 1件: 94
125 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04024 Lapatinib 3件: 34, 74, 75
126 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D07907 Erlotinib 1件: 94
127 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D08108 Lapatinib 3件: 34, 74, 75
128 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11251 Icotinib 1件: 34
129 EGFR 3件: Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11772 Tesevatinib 1件: 67
130 F2 1件: Regulation of actin cytoskeleton D06410 Thrombomodulin Alfa 1件: 85
131 F2 1件: Regulation of actin cytoskeleton D07144 Dabigatran etexilate 1件: 51
132 F2 1件: Regulation of actin cytoskeleton D09707 Dabigatran 4件: 51, 85, 91, 124
133 FGFR1 3件: Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
134 FGFR1 3件: Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
135 FGFR3 2件: Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
136 FGFR3 2件: Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
137 FGFR2 2件: Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D05338 Palifermin 5件: 13, 36, 38, 39, 65
138 FGFR2 2件: Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
139 FGFR2 2件: Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
140 ITGA4 2件: Regulation of actin cytoskeleton, Yersinia infection D06590 Firategrast 1件: 13
141 ITGA4 2件: Regulation of actin cytoskeleton, Yersinia infection D06886 Natalizumab 6件: 13, 15, 25, 46, 63, 96
142 ITGA4 2件: Regulation of actin cytoskeleton, Yersinia infection D08083 Vedolizumab 3件: 94, 96, 97
143 ITGA4 2件: Regulation of actin cytoskeleton, Yersinia infection D10540 Abrilumab 2件: 96, 97
144 ITGAL 4件: Regulation of actin cytoskeleton, Staphylococcus aureus infection, Rheumatoid arthritis, Viral myocarditis D03959 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96
145 ITGB7 2件: Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D08083 Vedolizumab 3件: 94, 96, 97
146 ITGB7 2件: Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D09901 Etrolizumab 2件: 96, 97
147 ITGB7 2件: Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D10540 Abrilumab 2件: 96, 97
148 PDGFRA 1件: Regulation of actin cytoskeleton D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
149 PDGFRA 1件: Regulation of actin cytoskeleton D06402 Sunitinib 2件: 28, 34
150 PDGFRA 1件: Regulation of actin cytoskeleton D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
151 PDGFRA 1件: Regulation of actin cytoskeleton D08552 Sunitinib 2件: 28, 34
152 PDGFRA 1件: Regulation of actin cytoskeleton D08953 Nilotinib 5件: 6, 8, 34, 51, 86
153 PDGFRA 1件: Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
154 PDGFRB 1件: Regulation of actin cytoskeleton D03658 Dasatinib 2件: 51, 85
155 PDGFRB 1件: Regulation of actin cytoskeleton D06272 Sorafenib 2件: 34, 86
156 PDGFRB 1件: Regulation of actin cytoskeleton D06402 Sunitinib 2件: 28, 34
157 PDGFRB 1件: Regulation of actin cytoskeleton D06414 Dasatinib 2件: 51, 85
158 PDGFRB 1件: Regulation of actin cytoskeleton D08524 Sorafenib 2件: 34, 86
159 PDGFRB 1件: Regulation of actin cytoskeleton D08552 Sunitinib 2件: 28, 34
160 PDGFRB 1件: Regulation of actin cytoskeleton D08953 Nilotinib 5件: 6, 8, 34, 51, 86
161 PDGFRB 1件: Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
162 PIK3CA 18件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
163 PIK3CB 18件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
164 PIK3CD 18件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
165 PIK3CD 18件: Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
166 MAP2K1 15件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
167 MAP2K1 15件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
168 MAP2K1 15件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
169 MAP2K1 15件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
170 MAP2K2 13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
171 MAP2K2 13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
172 MAP2K2 13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
173 MAP2K2 13件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
174 RAF1 12件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D06272 Sorafenib 2件: 34, 86
175 RAF1 12件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D08524 Sorafenib 2件: 34, 86
176 ROCK1 7件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, TGF-beta signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Yersinia infection D07941 Fasudil 4件: 2, 5, 7, 51
177 SRC 9件: VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib 2件: 2, 67
178 SRC 9件: VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib 2件: 51, 85
179 SRC 9件: VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib 2件: 51, 85
180 SRC 9件: VEGF signaling pathway, Tight junction, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Shigellosis, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib 3件: 6, 89, 272
181 BRAF 5件: Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D06272 Sorafenib 2件: 34, 86
182 BRAF 5件: Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D08524 Sorafenib 2件: 34, 86
183 BRAF 5件: Vascular smooth muscle contraction, Serotonergic synapse, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer D10064 Dabrafenib 1件: 34
184 CXCR4 2件: Viral protein interaction with cytokine and cytokine receptor, Regulation of actin cytoskeleton D08971 Plerixafor 6件: 19, 20, 51, 65, 285, 299
185 FGF23 1件: Regulation of actin cytoskeleton D10913 Burosumab 1件: 238
186 ROCK2 8件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection D07941 Fasudil 4件: 2, 5, 7, 51
187 ROCK2 8件: Sphingolipid signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Regulation of actin cytoskeleton, Shigellosis, Salmonella infection, Yersinia infection D11815 Belumosudil 1件: 51