Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	HDAC6	2件: Neutrophil extracellular trap formation, Viral carcinogenesis	D06320	Vorinostat	3件: 19, 75, 96
2	HDAC5	2件: Neutrophil extracellular trap formation, Viral carcinogenesis	D06320	Vorinostat	3件: 19, 75, 96
3	MAPK14	32件: Rap1 signaling pathway, Sphingolipid signaling pathway, Oocyte meiosis, VEGF signaling pathway, ...	D09639	Losmapimod	2件: 113, 222
4	MAPK14	32件: Rap1 signaling pathway, Sphingolipid signaling pathway, Oocyte meiosis, VEGF signaling pathway, ...	D10959	Neflamapimod	1件: 8
5	ELANE	3件: Neutrophil extracellular trap formation, Transcriptional misregulation in cancer, Systemic lupus ...	D03788	Sivelestat	3件: 13, 85, 96
6	MTOR	15件: Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Neutrophil extracellular trap fo ...	D00753	Sirolimus	41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 9 ...
7	MTOR	15件: Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Neutrophil extracellular trap fo ...	D02714	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
8	MTOR	15件: Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Neutrophil extracellular trap fo ...	D06068	Temsirolimus	4件: 13, 34, 89, 331
9	HDAC1	6件: Notch signaling pathway, Neutrophil extracellular trap formation, Thyroid hormone signaling path ...	D06320	Vorinostat	3件: 19, 75, 96
10	HDAC2	6件: Notch signaling pathway, Neutrophil extracellular trap formation, Thyroid hormone signaling path ...	D06320	Vorinostat	3件: 19, 75, 96

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