Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ACE 1件: Renin-angiotensin system D00251 Captopril 8件: 6, 17, 46, 86, 96, 97, 107, 271
2 ACE 1件: Renin-angiotensin system D00362 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222
3 ACE 1件: Renin-angiotensin system D00421 Ramipril 7件: 46, 49, 66, 67, 113, 218, 257
4 ACE 1件: Renin-angiotensin system D00459 Quinapril 1件: 19
5 ACE 1件: Renin-angiotensin system D00620 Benazepril 4件: 49, 57, 218, 224
6 ACE 1件: Renin-angiotensin system D00621 Enalapril 6件: 19, 46, 66, 113, 210, 222
7 ACE 1件: Renin-angiotensin system D00623 Moexipril 1件: 93
8 ACE 1件: Renin-angiotensin system D00624 Perindopril 4件: 58, 113, 167, 222
9 ACE 1件: Renin-angiotensin system D01069 Cilazapril 1件: 66
10 ACE 1件: Renin-angiotensin system D03752 Quinapril 1件: 19
11 ACE 1件: Renin-angiotensin system D03753 Perindopril 4件: 58, 113, 167, 222
12 ACE 1件: Renin-angiotensin system D07499 Benazepril 4件: 49, 57, 218, 224
13 ACE 1件: Renin-angiotensin system D07699 Cilazapril 1件: 66
14 ACE 1件: Renin-angiotensin system D07892 Enalapril 6件: 19, 46, 66, 113, 210, 222
15 ACE 1件: Renin-angiotensin system D08068 Imidapril 1件: 67
16 ACE 1件: Renin-angiotensin system D08131 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222
17 ACE 1件: Renin-angiotensin system D08225 Moexipril 1件: 93
18 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00150 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
19 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00357 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
20 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00400 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224
21 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00522 Candesartan cilexetil 1件: 67
22 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00522 Candesartan 2件: 58, 67
23 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00523 Irbesartan 4件: 66, 167, 168, 222
24 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00626 Candesartan cilexetil 1件: 67
25 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D00627 Telmisartan 2件: 66, 67
26 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D02014 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
27 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D08146 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
28 AGTR1 2件: Vascular smooth muscle contraction, Renin-angiotensin system D11776 Sparsentan 3件: 66, 218, 222
29 AGTR2 1件: Renin-angiotensin system D00150 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
30 AGTR2 1件: Renin-angiotensin system D02014 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224
31 ANPEP 1件: Renin-angiotensin system D00087 Ubenimex 1件: 86
32 MME 1件: Renin-angiotensin system D10225 Sacubitril 1件: 58
33 REN 1件: Renin-angiotensin system D03208 Aliskiren 3件: 66, 167, 222