Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CYP11B1	4件: Steroid hormone biosynthesis, Metabolic pathways, Cortisol synthesis and secretion, Cushing synd ...	D00410	Metyrapone	2件: 75, 193
2	CYP11B1	4件: Steroid hormone biosynthesis, Metabolic pathways, Cortisol synthesis and secretion, Cushing synd ...	D05019	Metyrapone	2件: 75, 193
3	CYP17A1	6件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling p ...	D00351	Ketoconazole	3件: 8, 13, 75
4	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00150	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224
5	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00357	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
6	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00400	Valsartan	7件: 57, 58, 66, 75, 218, 222, 224
7	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00522	Candesartan cilexetil	1件: 67
8	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00522	Candesartan	2件: 58, 67
9	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00523	Irbesartan	4件: 66, 167, 168, 222
10	AGTR1	9件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth musc ...	D00626	Candesartan cilexetil	1件: 67

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