Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CPT1A	3件: PPAR signaling pathway, Thermogenesis, Insulin resistance	D05442	Perhexiline	2件: 58, 272
2	CPT1A	3件: PPAR signaling pathway, Thermogenesis, Insulin resistance	D08340	Perhexiline	2件: 58, 272
3	CPT1B	3件: PPAR signaling pathway, Thermogenesis, Insulin resistance	D05442	Perhexiline	2件: 58, 272
4	CPT1B	3件: PPAR signaling pathway, Thermogenesis, Insulin resistance	D08340	Perhexiline	2件: 58, 272
5	MTOR	23件: Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Longevit ...	D00753	Sirolimus	41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 9 ...
6	MTOR	23件: Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Longevit ...	D02714	Everolimus	9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
7	MTOR	23件: Phospholipase D signaling pathway, mTOR signaling pathway, PI3K-Akt signaling pathway, Longevit ...	D06068	Temsirolimus	4件: 13, 34, 89, 331
8	IL6	25件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D01583	Pirfenidone	11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
9	IL6	25件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D08976	Pomalidomide	6件: 28, 34, 51, 85, 227, 331
10	IL6	25件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D09669	Siltuximab	2件: 28, 331

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