Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CFTR 4件: Tight junction, Gastric acid secretion, Pancreatic secretion, Vibrio cholerae infection D09916 Ivacaftor 1件: 299
2 CFTR 4件: Tight junction, Gastric acid secretion, Pancreatic secretion, Vibrio cholerae infection D10134 Lumacaftor 1件: 299
3 CFTR 4件: Tight junction, Gastric acid secretion, Pancreatic secretion, Vibrio cholerae infection D11041 Tezacaftor 1件: 299
4 CFTR 4件: Tight junction, Gastric acid secretion, Pancreatic secretion, Vibrio cholerae infection D11423 Deutivacaftor 1件: 299
5 CFTR 4件: Tight junction, Gastric acid secretion, Pancreatic secretion, Vibrio cholerae infection D11507 Elexacaftor 1件: 299
6 CFTR 4件: Tight junction, Gastric acid secretion, Pancreatic secretion, Vibrio cholerae infection D11724 Galicaftor 1件: 299
7 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00113 Atropine 2件: 2, 299
8 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00138 Scopolamine 1件: 2
9 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00270 Chlorpromazine 1件: 254
10 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00397 Tropicamide 3件: 6, 13, 19
11 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00465 Oxybutynin 3件: 6, 13, 53
12 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00481 Propantheline 1件: 26
13 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00525 Pilocarpine 3件: 6, 53, 299
14 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00646 Tolterodine 2件: 17, 53
15 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00661 Cevimeline 1件: 53
16 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00722 Oxybutynin 3件: 6, 13, 53
17 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00765 Rocuronium 1件: 296
18 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00787 Trihexyphenidyl 2件: 5, 6
19 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D00789 Chlorpromazine 1件: 254
20 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01000 Bethanechol 1件: 98
21 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01077 Atropine 2件: 2, 299
22 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01148 Tolterodine 2件: 17, 53
23 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01269 Solifenacin 3件: 6, 13, 53
24 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D01699 Darifenacin 2件: 6, 13
25 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D02069 Atropine 2件: 2, 299
26 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D02200 Pilocarpine 3件: 6, 53, 299
27 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D02212 Ipratropium 2件: 6, 86
28 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03011 Atropine 2件: 2, 299
29 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03274 Chlorpromazine 1件: 254
30 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03654 Darifenacin 2件: 6, 13
31 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D03814 Atropine 2件: 2, 299
32 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D04034 Chlorpromazine 1件: 254
33 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D05478 Pilocarpine 3件: 6, 53, 299
34 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07226 Fesoterodine 1件: 6
35 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D07667 Cevimeline 1件: 53
36 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08441 Propiverine 1件: 226
37 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08522 Solifenacin 3件: 6, 13, 53
38 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D08638 Trihexyphenidyl 2件: 5, 6
39 CHRM3 8件: Neuroactive ligand-receptor interaction, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine 1件: 156
40 HRH2 2件: Neuroactive ligand-receptor interaction, Gastric acid secretion D00295 Cimetidine 2件: 2, 254
41 HRH2 2件: Neuroactive ligand-receptor interaction, Gastric acid secretion D00318 Famotidine 7件: 6, 46, 61, 86, 98, 107, 300
42 HRH2 2件: Neuroactive ligand-receptor interaction, Gastric acid secretion D00422 Ranitidine 2件: 13, 65
43 HRH2 2件: Neuroactive ligand-receptor interaction, Gastric acid secretion D00673 Ranitidine 2件: 13, 65
44 HRH2 2件: Neuroactive ligand-receptor interaction, Gastric acid secretion D03503 Cimetidine 2件: 2, 254
45 HRH2 2件: Neuroactive ligand-receptor interaction, Gastric acid secretion D08040 Histamine 1件: 13
46 KCNQ1 4件: Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D00636 Amiodarone 2件: 28, 127
47 KCNQ1 4件: Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D02910 Amiodarone 2件: 28, 127
48 KCNQ1 4件: Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection D09569 Ezogabine 2件: 2, 144
49 ATP1A1 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00297 Digitoxin 1件: 299
50 ATP1A1 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00298 Digoxin 3件: 8, 46, 210
51 ATP1A2 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00297 Digitoxin 1件: 299
52 ATP1A2 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00298 Digoxin 3件: 8, 46, 210
53 ATP1A3 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00297 Digitoxin 1件: 299
54 ATP1A3 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00298 Digoxin 3件: 8, 46, 210
55 ATP1A4 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00297 Digitoxin 1件: 299
56 ATP1A4 9件: Insulin secretion, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Proximal tubule bicarbonate reclamation, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Protein digestion and absorption, Mineral absorption D00298 Digoxin 3件: 8, 46, 210
57 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D00355 Lansoprazole 7件: 63, 71, 85, 98, 166, 222, 299
58 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D00455 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
59 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D00724 Rabeprazole 2件: 2, 51
60 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D01207 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
61 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D01984 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
62 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D02593 Pantoprazole 2件: 13, 65
63 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D04056 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
64 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D05259 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
65 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D05261 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
66 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D05353 Pantoprazole 2件: 13, 65
67 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D07917 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
68 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D08463 Rabeprazole 2件: 2, 51
69 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D08903 Dexlansoprazole 1件: 98
70 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D09339 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
71 ATP4A 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D11784 Vonoprazan 2件: 63, 98
72 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D00355 Lansoprazole 7件: 63, 71, 85, 98, 166, 222, 299
73 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D00455 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
74 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D00724 Rabeprazole 2件: 2, 51
75 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D01207 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
76 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D01984 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
77 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D02593 Pantoprazole 2件: 13, 65
78 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D04056 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
79 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D05259 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
80 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D05261 Omeprazole 16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
81 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D05353 Pantoprazole 2件: 13, 65
82 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D07917 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
83 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D08463 Rabeprazole 2件: 2, 51
84 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D08903 Dexlansoprazole 1件: 98
85 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D09339 Esomeprazole 8件: 13, 46, 86, 98, 107, 113, 298, 299
86 ATP4B 3件: Oxidative phosphorylation, Metabolic pathways, Gastric acid secretion D11784 Vonoprazan 2件: 63, 98
87 SSTR2 3件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D00442 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227
88 SSTR2 3件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D06495 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227
89 SSTR2 3件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D07431 Somatostatin 2件: 67, 78
90 SSTR2 3件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D10147 Pasireotide 3件: 67, 74, 75
91 CA2 5件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Gastric acid secretion, Pancreatic secretion D00218 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230
92 CA2 5件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Gastric acid secretion, Pancreatic secretion D00518 Diclofenamide 1件: 114
93 CA2 5件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Gastric acid secretion, Pancreatic secretion D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
94 CA2 5件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Gastric acid secretion, Pancreatic secretion D00653 Dorzolamide 1件: 90
95 CA2 5件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Gastric acid secretion, Pancreatic secretion D01196 Acetazolamide 8件: 13, 86, 90, 115, 154, 155, 225, 230
96 CA2 5件: Nitrogen metabolism, Metabolic pathways, Proximal tubule bicarbonate reclamation, Gastric acid secretion, Pancreatic secretion D07871 Dorzolamide 1件: 90