Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	IFNG	16件: Proteasome, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Natural killer ...	D04242	Fontolizumab	1件: 46
2	IFNG	16件: Proteasome, Necroptosis, TGF-beta signaling pathway, Osteoclast differentiation, Natural killer ...	D11120	Emapalumab	2件: 49, 107
3	IL1B	21件: MAPK signaling pathway, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, ...	D01583	Pirfenidone	11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
4	IL1B	21件: MAPK signaling pathway, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, ...	D06635	Rilonacept	4件: 51, 106, 107, 266
5	IL1B	21件: MAPK signaling pathway, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, ...	D09315	Canakinumab	10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
6	IL1B	21件: MAPK signaling pathway, NF-kappa B signaling pathway, Necroptosis, Osteoclast differentiation, ...	D09911	Gevokizumab	4件: 41, 50, 56, 269
7	IL6	19件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D01583	Pirfenidone	11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
8	IL6	19件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D08976	Pomalidomide	6件: 28, 34, 51, 85, 227, 331
9	IL6	19件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D09669	Siltuximab	2件: 28, 331
10	IL6	19件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll ...	D10080	Sirukumab	2件: 41, 46

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