Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
2 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
3 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
4 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
5 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
6 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
7 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
8 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
9 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
CFB 1件: CFB 💬 |
D12251 D12251 💬 |
Iptacopan | 061 5件: 61, 62, 66, 109, 222 💬 |
10 | Complement and coagulation cascades 💬 Related to 17 target genes, 28 drugs (DrugBank) and 45 diseases in DDrare |
MASP2 1件: MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 4件: 64, 66, 109, 222 💬 |
11 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
12 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
13 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
14 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
15 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
CFB 1件: CFB 💬 |
D12251 D12251 💬 |
Iptacopan | 061 5件: 61, 62, 66, 109, 222 💬 |
16 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
MASP2 1件: MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 4件: 64, 66, 109, 222 💬 |
17 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
18 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
19 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
20 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
21 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
22 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
23 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
24 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
25 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
26 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
27 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
28 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
29 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
30 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
31 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
32 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
33 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
34 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
35 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
36 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
37 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
38 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
39 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
40 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |
41 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
CFB 1件: CFB 💬 |
D12251 D12251 💬 |
Iptacopan | 061 5件: 61, 62, 66, 109, 222 💬 |
42 | Staphylococcus aureus infection 💬 Related to 26 target genes, 19 drugs (DrugBank) and 34 diseases in DDrare |
MASP2 1件: MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 4件: 64, 66, 109, 222 💬 |
43 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
C5 1件: C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 2件: 62, 109 💬 |
44 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
C5 1件: C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 7件: 11, 13, 14, 61, 62, 109, 222 💬 |
45 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
C5 1件: C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 3件: 62, 109, 162 💬 |
46 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
C5 1件: C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 7件: 2 , 11, 13, 50, 62, 66, 109 💬 |