Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
2 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
3 Calcium signaling pathway 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
4 Calcium signaling pathway 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
5 Calcium signaling pathway 💬
3件: HTR2A, HTR2B, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
6 cAMP signaling pathway 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
7 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
8 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
9 Circadian entrainment 💬
2件: MTNR1A, MTNR1B 💬 D08170 💬 Melatonin 12件:  6 ,  8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬
10 Cortisol synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
11 Cortisol synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
12 Cushing syndrome 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
13 Cushing syndrome 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
14 ECM-receptor interaction 💬
1件: SV2A 💬 D08879 💬 Brivaracetam 2件: 149, 309 💬
15 ECM-receptor interaction 💬
3件: SV2A, SV2B, SV2C 💬 D11842 💬 Padsevonil 1件: 149 💬
16 Estrogen signaling pathway 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
17 GABAergic synapse 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
18 Gap junction 💬
3件: HTR2A, HTR2B, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
19 GnRH secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
20 GnRH secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
21 GnRH secretion 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
22 Inflammatory mediator regulation of TRP channels 💬
3件: HTR2A, HTR2B, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
23 Insulin secretion 💬
1件: SNAP25 💬 D00783 💬 Botulinum toxin type A 13件:  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
24 MAPK signaling pathway 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
25 MAPK signaling pathway 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
26 Morphine addiction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
27 Neuroactive ligand-receptor interaction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
28 Neuroactive ligand-receptor interaction 💬
3件: HTR2A, HTR2B, HTR2C 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
29 Neuroactive ligand-receptor interaction 💬
2件: MTNR1A, MTNR1B 💬 D08170 💬 Melatonin 12件:  6 ,  8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬
30 Serotonergic synapse 💬
4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
31 Synaptic vesicle cycle 💬
1件: SLC6A4 💬 D07945 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
32 Synaptic vesicle cycle 💬
1件: SNAP25 💬 D00783 💬 Botulinum toxin type A 13件:  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬
33 Taste transduction 💬
2件: GABBR1, GABBR2 💬 D00241 💬 Baclofen 7件:  2 , 10, 13, 18, 65, 149, 206 💬
34 Taste transduction 💬
2件: SCN3A, SCN9A 💬 D07299 💬 Lacosamide 3件:  2 , 46, 149 💬
35 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
36 Type II diabetes mellitus 💬
1件: CACNA1G 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬