Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
2 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
3 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
4 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
5 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
6 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
7 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
8 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
9 | Circadian entrainment 💬 Related to 21 target genes, 31 drugs (DrugBank) and 56 diseases in DDrare |
MTNR1A 2件: MTNR1A, MTNR1B 💬 |
D08170 D08170 💬 |
Melatonin | 006 12件: 6 , 8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬 |
10 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
11 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
12 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
13 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
14 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A 1件: SV2A 💬 |
D08879 D08879 💬 |
Brivaracetam | 149 2件: 149, 309 💬 |
15 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
SV2A 3件: SV2A, SV2B, SV2C 💬 |
D11842 D11842 💬 |
Padsevonil | 149 1件: 149 💬 |
16 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
17 | GABAergic synapse 💬 Related to 28 target genes, 38 drugs (DrugBank) and 56 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
18 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
19 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
20 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
21 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
22 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
23 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
24 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
25 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
26 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
27 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
28 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
29 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
MTNR1A 2件: MTNR1A, MTNR1B 💬 |
D08170 D08170 💬 |
Melatonin | 006 12件: 6 , 8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬 |
30 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
HTR2A 4件: HTR2A, HTR2B, HTR2C, SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
31 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 39 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
32 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 39 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
33 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
34 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
SCN3A 2件: SCN3A, SCN9A 💬 |
D07299 D07299 💬 |
Lacosamide | 002 3件: 2 , 46, 149 💬 |
35 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G 1件: CACNA1G 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
36 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
CACNA1G 1件: CACNA1G 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |