Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Calcium signaling pathway 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
2 Calcium signaling pathway 💬
 2件: EDNRA, EDNRB 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
3 Calcium signaling pathway 💬
 2件: EDNRA, EDNRB 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
4 cAMP signaling pathway 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
5 cAMP signaling pathway 💬
 1件: EDNRA 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
6 cAMP signaling pathway 💬
 1件: EDNRA 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
7 cGMP-PKG signaling pathway 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
8 cGMP-PKG signaling pathway 💬
 2件: EDNRA, EDNRB 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
9 cGMP-PKG signaling pathway 💬
 2件: EDNRA, EDNRB 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
10 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 D02229 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
11 cGMP-PKG signaling pathway 💬
 1件: PDE5A 💬 D08514 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
12 Chemical carcinogenesis - receptor activation 💬
 1件: AR 💬 D00462 💬 Oxandrolone 2件: 211, 285 💬
13 Melanogenesis 💬
 1件: EDNRB 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
14 Melanogenesis 💬
 1件: EDNRB 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
15 Metabolic pathways 💬
 1件: PDE5A 💬 D02229 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
16 Metabolic pathways 💬
 1件: PDE5A 💬 D08514 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
17 Neuroactive ligand-receptor interaction 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
18 Neuroactive ligand-receptor interaction 💬
 2件: EDNRA, EDNRB 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
19 Neuroactive ligand-receptor interaction 💬
 2件: EDNRA, EDNRB 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
20 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D00407 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
21 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D00751 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
22 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D00979 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
23 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D05000 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
24 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D05001 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
25 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D05002 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
26 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 D05000 💬 Methylprednisolone hemisuccinate 7件: 13, 49, 50, 51, 53, 97, 211 💬
27 Oocyte meiosis 💬
 1件: AR 💬 D00462 💬 Oxandrolone 2件: 211, 285 💬
28 Pathways in cancer 💬
 1件: AR 💬 D00462 💬 Oxandrolone 2件: 211, 285 💬
29 Pathways in cancer 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
30 Pathways in cancer 💬
 2件: EDNRA, EDNRB 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
31 Pathways in cancer 💬
 2件: EDNRA, EDNRB 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
32 Prostate cancer 💬
 1件: AR 💬 D00462 💬 Oxandrolone 2件: 211, 285 💬
33 Purine metabolism 💬
 1件: PDE5A 💬 D02229 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
34 Purine metabolism 💬
 1件: PDE5A 💬 D08514 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
35 Relaxin signaling pathway 💬
 1件: EDNRB 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
36 Relaxin signaling pathway 💬
 1件: EDNRB 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
37 Renin secretion 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
38 Renin secretion 💬
 1件: EDNRA 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
39 Renin secretion 💬
 1件: EDNRA 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
40 Vascular smooth muscle contraction 💬
 1件: EDNRA 💬 D07077 💬 Ambrisentan 7件: 51, 84, 85, 86, 88, 210, 211 💬
41 Vascular smooth muscle contraction 💬
 1件: EDNRA 💬 D01227 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
42 Vascular smooth muscle contraction 💬
 1件: EDNRA 💬 D07538 💬 Bosentan 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬

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