Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
2 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
3 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
4 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
CA2 1件: CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
5 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
6 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
7 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
8 | Carbohydrate digestion and absorption 💬 Related to 13 target genes, 17 drugs (DrugBank) and 29 diseases in DDrare |
TAS1R2 2件: TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 5件: 6 , 13, 67, 86, 230 💬 |
9 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
10 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
11 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
12 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
13 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
CA2 1件: CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
14 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
15 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
16 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
17 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
18 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
19 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
20 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
21 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
22 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
CA2 1件: CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
23 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
24 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
25 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
26 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
27 | Nitrogen metabolism 💬 Related to 14 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
28 | Nitrogen metabolism 💬 Related to 14 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
29 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PGR 1件: PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
30 | Pancreatic secretion 💬 Related to 12 target genes, 38 drugs (DrugBank) and 39 diseases in DDrare |
CA2 1件: CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
31 | Pancreatic secretion 💬 Related to 12 target genes, 38 drugs (DrugBank) and 39 diseases in DDrare |
CA2 1件: CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
32 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
33 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
34 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
35 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 36 drugs (DrugBank) and 40 diseases in DDrare |
PGR 1件: PGR 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
36 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
37 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |
38 | Proximal tubule bicarbonate reclamation 💬 Related to 6 target genes, 6 drugs (DrugBank) and 19 diseases in DDrare |
CA2 2件: CA2, CA4 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
39 | Proximal tubule bicarbonate reclamation 💬 Related to 6 target genes, 6 drugs (DrugBank) and 19 diseases in DDrare |
CA2 2件: CA2, CA4 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
40 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
41 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
42 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
TAS1R2 2件: TAS1R2, TAS1R3 💬 |
D02381 D02381 💬 |
Aspartame | 006 5件: 6 , 13, 67, 86, 230 💬 |
43 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D02367 D02367 💬 |
Desogestrel | 230 1件: 230 💬 |