Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
2 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
PML 2件: PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
4 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
5 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
6 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
7 | Aldosterone synthesis and secretion 💬 Related to 18 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
8 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
9 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
10 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
11 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
12 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
13 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
14 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
15 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
16 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
17 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
18 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
19 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
20 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
21 | Apelin signaling pathway 💬 Related to 12 target genes, 29 drugs (DrugBank) and 71 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
22 | Arrhythmogenic right ventricular cardiomyopathy 💬 Related to 11 target genes, 24 drugs (DrugBank) and 28 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
23 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
24 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
25 | Autophagy - animal 💬 Related to 13 target genes, 16 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
26 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 42 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
27 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
28 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
29 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
30 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
31 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
32 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
33 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
34 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
35 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
36 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
37 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
38 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CYSLTR1 1件: CYSLTR1 💬 |
D00529 D00529 💬 |
Montelukast | 006 8件: 6 , 13, 46, 61, 63, 85, 98, 228 💬 |
39 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
CYSLTR1 1件: CYSLTR1 💬 |
D08229 D08229 💬 |
Montelukast | 006 8件: 6 , 13, 46, 61, 63, 85, 98, 228 💬 |
40 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
41 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
42 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
43 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
44 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
45 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
46 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
47 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
48 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
49 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
50 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
51 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
AR 3件: AR, ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
52 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
53 | Choline metabolism in cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 52 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
54 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
55 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 2件: 63, 98 💬 |
56 | Colorectal cancer 💬 Related to 14 target genes, 20 drugs (DrugBank) and 50 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
57 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
58 | Cortisol synthesis and secretion 💬 Related to 14 target genes, 32 drugs (DrugBank) and 65 diseases in DDrare |
PDE8A 2件: PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
59 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
60 | Cushing syndrome 💬 Related to 23 target genes, 47 drugs (DrugBank) and 69 diseases in DDrare |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
61 | Cysteine and methionine metabolism 💬 Related to 3 target genes, 1 drug (DrugBank) and 3 diseases in DDrare |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 |
62 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
63 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MPL 1件: MPL 💬 |
D10306 D10306 💬 |
Avatrombopag | 060 2件: 60, 63 💬 |
64 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
MPL 1件: MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 4件: 60, 63, 64, 65 💬 |
65 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
66 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
67 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
68 | ECM-receptor interaction 💬 Related to 6 target genes, 9 drugs (DrugBank) and 15 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
69 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
70 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 7 target genes, 26 drugs (DrugBank) and 55 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
71 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
72 | Endocrine resistance 💬 Related to 20 target genes, 40 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
73 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
74 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
75 | ErbB signaling pathway 💬 Related to 12 target genes, 22 drugs (DrugBank) and 52 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
76 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
ESR1 2件: ESR1, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
77 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
RARA 1件: RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
78 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
79 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
80 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
81 | Gastric acid secretion 💬 Related to 12 target genes, 46 drugs (DrugBank) and 55 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 2件: 63, 98 💬 |
82 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
83 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
RARB 1件: RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
84 | Glioma 💬 Related to 14 target genes, 26 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
85 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
86 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
87 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
88 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
89 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
90 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
91 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
92 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 006 49件: 6 , 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
93 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
94 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
95 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
96 | HIF-1 signaling pathway 💬 Related to 22 target genes, 43 drugs (DrugBank) and 77 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
97 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
98 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
99 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
100 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
101 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
102 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
103 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
104 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
105 | Huntington disease 💬 Related to 24 target genes, 32 drugs (DrugBank) and 80 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
106 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
107 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
108 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
109 | Insulin signaling pathway 💬 Related to 12 target genes, 24 drugs (DrugBank) and 64 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
110 | Insulin signaling pathway 💬 Related to 12 target genes, 24 drugs (DrugBank) and 64 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
111 | Insulin signaling pathway 💬 Related to 12 target genes, 24 drugs (DrugBank) and 64 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
112 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
113 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
114 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
MPL 1件: MPL 💬 |
D10306 D10306 💬 |
Avatrombopag | 060 2件: 60, 63 💬 |
115 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
MPL 1件: MPL 💬 |
D08990 D08990 💬 |
Romiplostim | 060 4件: 60, 63, 64, 65 💬 |
116 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
117 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
118 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
119 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
120 | Leukocyte transendothelial migration 💬 Related to 12 target genes, 12 drugs (DrugBank) and 27 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
121 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
122 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
123 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
124 | Longevity regulating pathway 💬 Related to 11 target genes, 18 drugs (DrugBank) and 65 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
125 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 14 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
126 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
127 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
128 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
129 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 2件: 63, 98 💬 |
130 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
131 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 |
132 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
133 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
134 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
135 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
136 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 |
137 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
138 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
139 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
140 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
141 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
142 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
143 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
144 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
CYSLTR1 1件: CYSLTR1 💬 |
D00529 D00529 💬 |
Montelukast | 006 8件: 6 , 13, 46, 61, 63, 85, 98, 228 💬 |
145 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
CYSLTR1 1件: CYSLTR1 💬 |
D08229 D08229 💬 |
Montelukast | 006 8件: 6 , 13, 46, 61, 63, 85, 98, 228 💬 |
146 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00292 D00292 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
147 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00975 D00975 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
148 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D01510 D01510 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
149 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D01615 D01615 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
150 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D01632 D01632 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
151 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D01948 D01948 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
152 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D02174 D02174 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
153 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D02591 D02591 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
154 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D02592 D02592 💬 |
Dexamethasone | 013 25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 |
155 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
156 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
157 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
158 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
159 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
160 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 48件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬 |
161 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
162 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00980 D00980 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
163 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00981 D00981 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
164 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00982 D00982 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
165 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D01239 D01239 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
166 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D01998 D01998 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
167 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D02156 D02156 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
168 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D03301 D03301 💬 |
Prednisolone | 003 43件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307 💬 |
169 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 48件: 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
170 | Neutrophil extracellular trap formation 💬 Related to 34 target genes, 32 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
171 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
172 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
173 | Nicotinate and nicotinamide metabolism 💬 Related to 1 target gene, 3 drugs (DrugBank) and 7 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
174 | Non-small cell lung cancer 💬 Related to 20 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
RARB 1件: RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
175 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 14 diseases in DDrare |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
176 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 14 diseases in DDrare |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
177 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
AR 2件: AR, PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
178 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
179 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
180 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
181 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
182 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 2件: 63, 98 💬 |
183 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
184 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
185 | Pancreatic cancer 💬 Related to 19 target genes, 32 drugs (DrugBank) and 69 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
186 | Pancreatic secretion 💬 Related to 12 target genes, 38 drugs (DrugBank) and 39 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
187 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
188 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
189 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
190 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
AR 2件: AR, ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
191 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
192 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
PML 3件: PML, RARA, RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
193 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
194 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
195 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
196 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
197 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
198 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
199 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
200 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
201 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
202 | Primary immunodeficiency 💬 Related to 11 target genes, 21 drugs (DrugBank) and 27 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
203 | Primary immunodeficiency 💬 Related to 11 target genes, 21 drugs (DrugBank) and 27 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
204 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
205 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
206 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 36 drugs (DrugBank) and 40 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
207 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 36 drugs (DrugBank) and 40 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
208 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 36 drugs (DrugBank) and 40 diseases in DDrare |
PGR 1件: PGR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
209 | Prolactin signaling pathway 💬 Related to 19 target genes, 36 drugs (DrugBank) and 53 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
210 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
AR 1件: AR 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
211 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
212 | Proteasome 💬 Related to 2 target genes, 5 drugs (DrugBank) and 18 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
213 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
214 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
215 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
216 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
217 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
218 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
219 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
220 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
221 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 70 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
222 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
223 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
224 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
225 | Salivary secretion 💬 Related to 18 target genes, 65 drugs (DrugBank) and 62 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 016 5件: 16, 28, 49, 63, 222 💬 |
226 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
227 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
RARB 1件: RARB 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
228 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
229 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
230 | Spinocerebellar ataxia 💬 Related to 16 target genes, 23 drugs (DrugBank) and 68 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
231 | Spinocerebellar ataxia 💬 Related to 16 target genes, 23 drugs (DrugBank) and 68 diseases in DDrare |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬 |
232 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
233 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
234 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
235 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
236 | Taste transduction 💬 Related to 30 target genes, 84 drugs (DrugBank) and 69 diseases in DDrare |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
237 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
238 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
239 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
240 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
241 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
242 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA 1件: RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
243 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
244 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
ESR1 1件: ESR1 💬 |
D00289 D00289 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 |
245 | Thyroid hormone signaling pathway 💬 Related to 23 target genes, 38 drugs (DrugBank) and 65 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
246 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
247 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
PML 2件: PML, RARA 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
248 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
249 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
250 | Ubiquitin mediated proteolysis 💬 Related to 2 target genes, 2 drugs (DrugBank) and 11 diseases in DDrare |
PML 1件: PML 💬 |
D00094 D00094 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 |
251 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
252 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
253 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
254 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
255 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
256 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |