Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
2 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
3 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
4 | Alcoholism 💬 Related to 28 target genes, 73 drugs (DrugBank) and 54 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
5 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 3件: 5 , 7 , 127 💬 |
6 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
7 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
8 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
9 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
10 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
11 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
12 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
13 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 2件: DRD1, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
14 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
DRD1 2件: DRD1, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
15 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
16 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
17 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 3件: DRD1, DRD2, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
18 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
DRD1 3件: DRD1, DRD2, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
19 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
20 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
21 | Chemokine signaling pathway 💬 Related to 21 target genes, 26 drugs (DrugBank) and 49 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
22 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
23 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
24 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
25 | Cocaine addiction 💬 Related to 15 target genes, 62 drugs (DrugBank) and 51 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
26 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
27 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
28 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
29 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
30 | Focal adhesion 💬 Related to 26 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
31 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
32 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
33 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
34 | Gap junction 💬 Related to 25 target genes, 83 drugs (DrugBank) and 78 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
35 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
36 | Insulin secretion 💬 Related to 13 target genes, 41 drugs (DrugBank) and 46 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
37 | Leukocyte transendothelial migration 💬 Related to 12 target genes, 12 drugs (DrugBank) and 27 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
38 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
39 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 3件: 5 , 7 , 127 💬 |
40 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
ROCK1 1件: ROCK1 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
41 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
42 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
43 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
44 | Morphine addiction 💬 Related to 40 target genes, 64 drugs (DrugBank) and 75 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
45 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
46 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
47 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
48 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
49 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
50 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
51 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
52 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
53 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
54 | Parkinson disease 💬 Related to 24 target genes, 72 drugs (DrugBank) and 67 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 3件: 5 , 7 , 127 💬 |
55 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
56 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
57 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
MAPT 1件: MAPT 💬 |
D11210 D11210 💬 |
Flortaucipir | 005 3件: 5 , 7 , 127 💬 |
58 | Platelet activation 💬 Related to 22 target genes, 48 drugs (DrugBank) and 56 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
59 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
60 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D02004 D02004 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
61 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 3件: 5 , 6 , 7 💬 |
62 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00633 D00633 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
63 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 4件: 6 , 7 , 74, 299 💬 |
64 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
65 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
66 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
67 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
68 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 39 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
69 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
ROCK1 1件: ROCK1 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
70 | Tight junction 💬 Related to 11 target genes, 28 drugs (DrugBank) and 44 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
71 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
72 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
73 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |