Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00620 D00620 💬 |
Benazepril | 049 4件: 49, 57, 218, 224 💬 |
2 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D07499 D07499 💬 |
Benazepril | 049 4件: 49, 57, 218, 224 💬 |
3 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
4 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D01069 D01069 💬 |
Cilazapril | 066 1件: 66 💬 |
5 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D07699 D07699 💬 |
Cilazapril | 066 1件: 66 💬 |
6 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
7 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 6件: 19, 46, 66, 113, 210, 222 💬 |
8 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D08068 D08068 💬 |
Imidapril | 067 1件: 67 💬 |
9 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
10 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 7件: 19, 46, 49, 66, 67, 113, 222 💬 |
11 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00623 D00623 💬 |
Moexipril | 093 1件: 93 💬 |
12 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D08225 D08225 💬 |
Moexipril | 093 1件: 93 💬 |
13 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00624 D00624 💬 |
Perindopril | 058 4件: 58, 113, 167, 222 💬 |
14 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 4件: 58, 113, 167, 222 💬 |
15 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00459 D00459 💬 |
Quinapril | 019 1件: 19 💬 |
16 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 1件: 19 💬 |
17 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00421 D00421 💬 |
Ramipril | 046 7件: 46, 49, 66, 67, 113, 218, 257 💬 |
18 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
19 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
20 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 2件: 58, 67 💬 |
21 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 1件: 67 💬 |
22 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 1件: 67 💬 |
23 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 4件: 66, 167, 168, 222 💬 |
24 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
25 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
26 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 3件: 66, 218, 222 💬 |
27 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 2件: 66, 67 💬 |
28 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
29 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
CPT1B 2件: CPT1B, CPT2 💬 |
D05442 D05442 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
30 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
CPT1B 2件: CPT1B, CPT2 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
31 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
32 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
33 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
INSR 1件: INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 2件: 96, 156 💬 |
34 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
INSR 1件: INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 2件: 96, 156 💬 |
35 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
36 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
37 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
38 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
39 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 4件: 13, 34, 89, 331 💬 |
40 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 4件: 46, 51, 53, 271 💬 |
41 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PARP1 1件: PARP1 💬 |
D09730 D09730 💬 |
Olaparib | 086 2件: 86, 285 💬 |
42 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
43 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
44 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
45 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D11208 D11208 💬 |
Elafibranor | 093 1件: 93 💬 |
46 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
47 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D10711 D10711 💬 |
Pemafibrate | 093 1件: 93 💬 |
48 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PRKCD 1件: PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 1件: 97 💬 |
49 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
50 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
REN 1件: REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 3件: 66, 167, 222 💬 |
51 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 |