Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
2 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 |
3 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 |
4 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 1件: 13 💬 |
5 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 |
6 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
7 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
BTK 1件: BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 2件: 300, 331 💬 |
8 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
9 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD19 1件: CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 4件: 11, 13, 51, 300 💬 |
10 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD3D 3件: CD3D, CD3E, CD3G 💬 |
D05092 D05092 💬 |
Muromonab | 060 3件: 60, 96, 97 💬 |
11 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD3D 3件: CD3D, CD3E, CD3G 💬 |
D08959 D08959 💬 |
Otelixizumab | 046 1件: 46 💬 |
12 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD3D 3件: CD3D, CD3E, CD3G 💬 |
D06314 D06314 💬 |
Visilizumab | 096 2件: 96, 97 💬 |
13 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD3E 1件: CD3E 💬 |
D11463 D11463 💬 |
Mosunetuzumab | 049 1件: 49 💬 |
14 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD40 1件: CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 1件: 222 💬 |
15 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD40 1件: CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 2件: 49, 53 💬 |
16 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD40 1件: CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 2件: 53, 97 💬 |
17 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CD58 1件: CD58 💬 |
D02800 D02800 💬 |
Alefacept | 037 6件: 37, 60, 65, 164, 284, 285 💬 |
18 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
CDK4 2件: CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
19 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
HDAC1 2件: HDAC1, HDAC2 💬 |
D06320 D06320 💬 |
Vorinostat | 019 3件: 19, 75, 96 💬 |
20 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
HLA-A 20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G 💬 |
D04318 D04318 💬 |
Glatiramer | 002 4件: 2 , 13, 96, 156 💬 |
21 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 1件: 49 💬 |
22 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 1件: 49 💬 |
23 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 2件: 46, 49 💬 |
24 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 6件: 13, 25, 26, 28, 56, 96 💬 |
25 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 1件: 56 💬 |
26 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 2件: 25, 34 💬 |
27 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 4件: 13, 26, 96, 97 💬 |
28 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 1件: 13 💬 |
29 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 1件: 13 💬 |
30 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IL6 1件: IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 2件: 28, 331 💬 |
31 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
32 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IL6 2件: IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
33 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
IL6 2件: IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
34 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
ITGAL 1件: ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
35 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
36 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬 |
37 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 5件: 46, 51, 60, 97, 228 💬 |
38 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 1件: 228 💬 |
39 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
40 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 2件: JAK1, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
41 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
42 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
43 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
44 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 4件: 46, 51, 53, 271 💬 |
45 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
46 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
47 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
48 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
SYK 1件: SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 |
49 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
50 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
51 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
52 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
53 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
54 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 |
55 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 1件: 46 💬 |
56 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 1件: 46 💬 |
57 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
58 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TYK2 1件: TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 2件: 96, 97 💬 |