Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
BCL2 1件: BCL2 💬 |
D10679 D10679 💬 |
Venetoclax | 028 1件: 28 💬 |
| 2 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
| 3 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CD19 1件: CD19 💬 |
D11757 D11757 💬 |
Inebilizumab | 011 4件: 11, 13, 51, 300 💬 |
| 4 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CDK4 2件: CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
| 5 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00113 D00113 💬 |
Atropine | 002 2件: 2 , 299 💬 |
| 6 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D01077 D01077 💬 |
Atropine | 002 2件: 2 , 299 💬 |
| 7 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D02069 D02069 💬 |
Atropine | 002 2件: 2 , 299 💬 |
| 8 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D03011 D03011 💬 |
Atropine | 002 2件: 2 , 299 💬 |
| 9 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D03814 D03814 💬 |
Atropine | 002 2件: 2 , 299 💬 |
| 10 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D01000 D01000 💬 |
Bethanechol | 098 1件: 98 💬 |
| 11 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 1件: 156 💬 |
| 12 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 13 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 14 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 15 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 1件: 254 💬 |
| 16 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D02212 D02212 💬 |
Ipratropium | 006 2件: 6 , 86 💬 |
| 17 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 3件: 6 , 13, 53 💬 |
| 18 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00722 D00722 💬 |
Oxybutynin | 006 3件: 6 , 13, 53 💬 |
| 19 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00481 D00481 💬 |
Propantheline | 026 1件: 26 💬 |
| 20 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
| 21 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00765 D00765 💬 |
Rocuronium | 296 1件: 296 💬 |
| 22 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00138 D00138 💬 |
Scopolamine | 002 1件: 2 💬 |
| 23 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00787 D00787 💬 |
Trihexyphenidyl | 005 2件: 5 , 6 💬 |
| 24 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 2件: 5 , 6 💬 |
| 25 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM1 2件: CHRM1, CHRM2 💬 |
D00397 D00397 💬 |
Tropicamide | 006 3件: 6 , 13, 19 💬 |
| 26 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM2 1件: CHRM2 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 1件: 6 💬 |
| 27 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM2 1件: CHRM2 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
| 28 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM2 1件: CHRM2 💬 |
D02200 D02200 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
| 29 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CHRM2 1件: CHRM2 💬 |
D05478 D05478 💬 |
Pilocarpine | 006 3件: 6 , 53, 299 💬 |
| 30 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF1 8件: CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
D06402 D06402 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 31 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF1 8件: CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 32 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF1R 3件: CSF1R, FLT3, KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 1件: 34 💬 |
| 33 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 34件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
| 34 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03247 D03247 💬 |
Lenograstim | 002 7件: 2 , 13, 16, 18, 19, 57, 65 💬 |
| 35 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D06889 D06889 💬 |
Pegfilgrastim | 060 1件: 60 💬 |
| 36 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 5件: 34, 51, 86, 89, 331 💬 |
| 37 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 1件: 94 💬 |
| 38 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
| 39 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
| 40 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
| 41 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D04024 D04024 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 42 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 2件: EGFR, ERBB2 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 43 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 44 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EPHA2 3件: EPHA2, KIT, PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 45 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EPHA2 3件: EPHA2, KIT, PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 46 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EPOR 1件: EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 10件: 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
| 47 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
EPOR 1件: EPOR 💬 |
D09946 D09946 💬 |
Peginesatide | 283 1件: 283 💬 |
| 48 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FGF23 1件: FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 1件: 238 💬 |
| 49 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 50 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FGFR1 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬 |
| 51 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 5件: 13, 36, 38, 39, 65 💬 |
| 52 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FLT1 3件: FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 1件: 34 💬 |
| 53 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FLT1 3件: FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 1件: 34 💬 |
| 54 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FLT3 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 55 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FLT3 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 56 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D11486 D11486 💬 |
Lonapegsomatropin | 078 1件: 78 💬 |
| 57 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D05394 D05394 💬 |
Pegvisomant | 078 1件: 78 💬 |
| 58 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D11194 D11194 💬 |
Somapacitan | 078 1件: 78 💬 |
| 59 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 60 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D11193 D11193 💬 |
Somavaratan | 078 1件: 78 💬 |
| 61 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 2件: GHR, IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 62 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 2件: GHR, IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
| 63 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 1件: 49 💬 |
| 64 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 1件: 49 💬 |
| 65 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 2件: 46, 49 💬 |
| 66 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 6件: 13, 25, 26, 28, 56, 96 💬 |
| 67 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 1件: 56 💬 |
| 68 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 2件: 25, 34 💬 |
| 69 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 4件: 13, 26, 96, 97 💬 |
| 70 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 1件: 13 💬 |
| 71 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 1件: 13 💬 |
| 72 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
| 73 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
| 74 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03058 D03058 💬 |
Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬 |
| 75 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL2RA 1件: IL2RA 💬 |
D03639 D03639 💬 |
Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬 |
| 76 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬 |
D00748 D00748 💬 |
Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬 |
| 77 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL4 1件: IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 1件: 46 💬 |
| 78 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
| 79 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6 1件: IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 80 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6 1件: IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
| 81 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6 1件: IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 2件: 28, 331 💬 |
| 82 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
| 83 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
| 84 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D11079 D11079 💬 |
Satralizumab | 011 2件: 11, 13 💬 |
| 85 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
| 86 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
INSR 1件: INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 1件: 299 💬 |
| 87 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
INSR 1件: INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 1件: 299 💬 |
| 88 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
INSR 1件: INSR 💬 |
D00085 D00085 💬 |
Insulin human | 096 2件: 96, 156 💬 |
| 89 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
INSR 1件: INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 2件: 96, 156 💬 |
| 90 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 1件: 13 💬 |
| 91 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
| 92 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
ITGA4 2件: ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 2件: 96, 97 💬 |
| 93 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
ITGA4 2件: ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 3件: 94, 96, 97 💬 |
| 94 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
ITGB7 1件: ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 2件: 96, 97 💬 |
| 95 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬 |
| 96 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 5件: 46, 51, 60, 97, 228 💬 |
| 97 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
| 98 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 99 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 1件: 228 💬 |
| 100 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
| 101 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 102 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
KDR 2件: KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
| 103 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
KIT 1件: KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 6件: 2 , 5 , 6 , 13, 46, 96 💬 |
| 104 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
KIT 2件: KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 105 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 106 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
KIT 3件: KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
| 107 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 108 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 109 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 110 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 111 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
| 112 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
| 113 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 4件: 13, 34, 89, 331 💬 |
| 114 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 4件: 46, 51, 53, 271 💬 |
| 115 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
NGF 1件: NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 2件: 226, 298 💬 |
| 116 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
NGFR 1件: NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 2件: 53, 90 💬 |
| 117 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PGF 3件: PGF, VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 2件: 90, 166 💬 |
| 118 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 119 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 120 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 24件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 121 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 24件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
| 122 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL 1件: PRL 💬 |
D00780 D00780 💬 |
Bromocriptine | 006 2件: 6 , 74 💬 |
| 123 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL 1件: PRL 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 2件: 6 , 74 💬 |
| 124 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL 1件: PRL 💬 |
D00987 D00987 💬 |
Cabergoline | 006 3件: 6 , 74, 75 💬 |
| 125 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
PRL 1件: PRL 💬 |
D01348 D01348 💬 |
Terguride | 051 2件: 51, 86 💬 |
| 126 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
| 127 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D02754 D02754 💬 |
Acitretin | 037 1件: 37 💬 |
| 128 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D02815 D02815 💬 |
Alitretinoin | 049 1件: 49 💬 |
| 129 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
RXRA 1件: RXRA 💬 |
D03106 D03106 💬 |
Bexarotene | 013 2件: 13, 75 💬 |
| 130 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
SYK 1件: SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 |
| 131 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 |
| 132 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 4件: 34, 166, 227, 301 💬 |
| 133 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
VWF 1件: VWF 💬 |
D11160 D11160 💬 |
Caplacizumab | 064 1件: 64 💬 |