Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Pyrimidine metabolism 💬	1件: DHODH 💬	D00749 💬	Leflunomide	12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
2	Pyrimidine metabolism 💬	1件: DHODH 💬	D10172 💬	Teriflunomide	3件: 13, 25, 26 💬
3	Pyrimidine metabolism 💬	1件: RRM1 💬	D01370 💬	Cladribine	3件: 11, 13, 94 💬
4	Pyrimidine metabolism 💬	1件: RRM1 💬	D03546 💬	Clofarabine	9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
5	Pyrimidine metabolism 💬	1件: RRM1 💬	D01907 💬	Fludarabine	19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
6	Pyrimidine metabolism 💬	1件: RRM1 💬	D07966 💬	Fludarabine	19件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
7	Pyrimidine metabolism 💬	1件: RRM2 💬	D00341 💬	Hydroxyurea	8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬
8	Pyrimidine metabolism 💬	1件: TYMS 💬	D01223 💬	Capecitabine	1件: 94 💬
9	Pyrimidine metabolism 💬	1件: TYMS 💬	D01244 💬	Tegafur	1件: 46 💬

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