Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
2 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
3 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 1件: 6 💬 |
4 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 1件: 6 💬 |
5 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 1件: 58 💬 |
6 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D02017 D02017 💬 |
Theophylline | 236 2件: 236, 299 💬 |
7 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 1件: 6 💬 |
8 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 2件: ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 3件: 13, 58, 65 💬 |
9 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2A 2件: ADORA2A, ADORA2B 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 1件: 46 💬 |
10 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
11 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D05429 D05429 💬 |
Aminophylline | 063 1件: 63 💬 |
12 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
13 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D01712 D01712 💬 |
Theophylline | 236 2件: 236, 299 💬 |
14 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
15 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADORA2B 1件: ADORA2B 💬 |
D06104 D06104 💬 |
Theophylline | 236 2件: 236, 299 💬 |
16 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D01692 D01692 💬 |
Alfuzosin | 013 1件: 13 💬 |
17 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D07124 D07124 💬 |
Alfuzosin | 013 1件: 13 💬 |
18 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D01965 D01965 💬 |
Silodosin | 006 2件: 6 , 13 💬 |
19 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00636 D00636 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
20 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D02910 D02910 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
21 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00255 D00255 💬 |
Carvedilol | 006 5件: 6 , 57, 86, 113, 210 💬 |
22 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D03415 D03415 💬 |
Carvedilol | 006 5件: 6 , 57, 86, 113, 210 💬 |
23 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 1件: 6 💬 |
24 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00608 D00608 💬 |
Doxazosin | 057 2件: 57, 67 💬 |
25 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D07874 D07874 💬 |
Doxazosin | 057 2件: 57, 67 💬 |
26 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
27 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00124 D00124 💬 |
Ephedrine | 011 1件: 11 💬 |
28 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00095 D00095 💬 |
Epinephrine | 046 3件: 46, 70, 96 💬 |
29 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00996 D00996 💬 |
Epinephrine | 046 3件: 46, 70, 96 💬 |
30 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D02149 D02149 💬 |
Epinephrine | 046 3件: 46, 70, 96 💬 |
31 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D02268 D02268 💬 |
Ergoloid mesylate | 006 2件: 6 , 206 💬 |
32 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08064 D08064 💬 |
Ifenprodil | 085 1件: 85 💬 |
33 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 3件: 118, 280, 288 💬 |
34 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 3件: 118, 280, 288 💬 |
35 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D01307 D01307 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
36 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
37 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 1件: 22 💬 |
38 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D05206 D05206 💬 |
Norepinephrine | 022 1件: 22 💬 |
39 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00454 D00454 💬 |
Olanzapine | 002 2件: 2 , 8 💬 |
40 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D06623 D06623 💬 |
Olanzapine | 002 2件: 2 , 8 💬 |
41 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00511 D00511 💬 |
Phenylephrine | 022 1件: 22 💬 |
42 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08365 D08365 💬 |
Phenylephrine | 022 1件: 22 💬 |
43 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00485 D00485 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
44 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D05648 D05648 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
45 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D05649 D05649 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
46 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
47 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00610 D00610 💬 |
Terazosin | 006 1件: 6 💬 |
48 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08569 D08569 💬 |
Terazosin | 006 1件: 6 💬 |
49 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
50 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
51 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 2件: 58, 67 💬 |
52 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00522 D00522 💬 |
Candesartan cilexetil | 067 1件: 67 💬 |
53 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 1件: 67 💬 |
54 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 4件: 66, 167, 168, 222 💬 |
55 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00357 D00357 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
56 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
57 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 2件: 66, 67 💬 |
58 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 7件: 57, 58, 66, 75, 218, 222, 224 💬 |
59 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AGTR1 2件: AGTR1, EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 3件: 66, 218, 222 💬 |
60 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AVPR1A 1件: AVPR1A 💬 |
D01236 D01236 💬 |
Conivaptan | 086 1件: 86 💬 |
61 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AVPR1A 1件: AVPR1A 💬 |
D07748 D07748 💬 |
Conivaptan | 086 1件: 86 💬 |
62 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AVPR1A 2件: AVPR1A, AVPR1B 💬 |
D06672 D06672 💬 |
Terlipressin | 299 1件: 299 💬 |
63 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
AVPR1A 2件: AVPR1A, AVPR1B 💬 |
D00101 D00101 💬 |
Vasopressin | 210 1件: 210 💬 |
64 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
65 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
66 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
67 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
68 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
69 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
70 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 1件: 67 💬 |
71 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
72 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
73 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
74 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 1件: 6 💬 |
75 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
76 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
77 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 2件: 50, 81 💬 |
78 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 1件: 90 💬 |
79 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
80 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
81 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
82 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
83 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 3件: 96, 140, 167 💬 |
84 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 3件: 96, 140, 167 💬 |
85 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
CALCA 1件: CALCA 💬 |
D11055 D11055 💬 |
Fremanezumab | 124 2件: 124, 226 💬 |
86 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
87 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
88 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
89 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
90 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 1件: 86 💬 |
91 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 1件: 51 💬 |
92 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 1件: 58 💬 |
93 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
94 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
95 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
96 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
97 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
98 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
NPR1 1件: NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 2件: 46, 58 💬 |
99 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
NPR1 2件: NPR1, NPR2 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 1件: 46 💬 |
100 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |
101 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PRKCD 4件: PRKCD, PRKCE, PRKCH, PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 1件: 97 💬 |
102 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D02720 D02720 💬 |
Beraprost | 086 1件: 86 💬 |
103 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D00106 D00106 💬 |
Epoprostenol | 086 1件: 86 💬 |
104 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D01337 D01337 💬 |
Epoprostenol | 086 1件: 86 💬 |
105 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D01385 D01385 💬 |
Ibudilast | 002 2件: 2 , 13 💬 |
106 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D02721 D02721 💬 |
Iloprost | 051 4件: 51, 84, 85, 86 💬 |
107 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D10725 D10725 💬 |
Ralinepag | 086 1件: 86 💬 |
108 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 047 6件: 47, 51, 70, 84, 86, 88 💬 |
109 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
PTGIR 1件: PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 |
110 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ROCK1 2件: ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 4件: 2 , 5 , 7 , 51 💬 |
111 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
ROCK2 1件: ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 1件: 51 💬 |