Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D10893 D10893 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 |
| 2 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D11478 D11478 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 |
| 3 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D11457 D11457 💬 |
Fenebrutinib | 013 1件: 13 💬 |
| 4 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D10223 D10223 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 |
| 5 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D12160 D12160 💬 |
Orelabrutinib | 013 3件: 13, 61, 63 💬 |
| 6 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
BTK 1件: BTK 💬 |
D11422 D11422 💬 |
Zanubrutinib | 300 2件: 300, 331 💬 |
| 7 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
CSF1 1件: CSF1 💬 |
D06402 D06402 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 8 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
CSF1 1件: CSF1 💬 |
D08552 D08552 💬 |
Sunitinib | 028 2件: 28, 34 💬 |
| 9 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
CSF1R 1件: CSF1R 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 1件: 34 💬 |
| 10 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
FYN 2件: FYN, LCK 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 11 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
FYN 2件: FYN, LCK 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 12 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D11082 D11082 💬 |
Anifrolumab | 046 2件: 46, 49 💬 |
| 13 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D03305 D03305 💬 |
Interferon alfa | 013 6件: 13, 25, 26, 28, 56, 96 💬 |
| 14 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00745 D00745 💬 |
Interferon alfa-2a | 056 1件: 56 💬 |
| 15 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D02745 D02745 💬 |
Interferon alfa-2b | 025 2件: 25, 34 💬 |
| 16 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D04554 D04554 💬 |
Interferon beta-1a | 013 4件: 13, 26, 96, 97 💬 |
| 17 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D00746 D00746 💬 |
Interferon beta-1b | 013 1件: 13 💬 |
| 18 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNAR1 2件: IFNAR1, IFNAR2 💬 |
D10483 D10483 💬 |
Peginterferon beta-1a | 013 1件: 13 💬 |
| 19 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 2件: 49, 107 💬 |
| 20 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNG 1件: IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 1件: 46 💬 |
| 21 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
| 22 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1A 1件: IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 1件: 51 💬 |
| 23 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
| 24 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1A 3件: IL1A, IL1B, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
| 25 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
| 26 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
| 27 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
| 28 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬 |
| 29 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10871 D10871 💬 |
Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬 |
| 30 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10944 D10944 💬 |
Itacitinib | 046 5件: 46, 51, 60, 97, 228 💬 |
| 31 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10653 D10653 💬 |
Peficitinib | 046 1件: 46 💬 |
| 32 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D09959 D09959 💬 |
Ruxolitinib | 228 1件: 228 💬 |
| 33 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
| 34 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬 |
| 35 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 36 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 37 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 38 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
MAP2K1 1件: MAP2K1 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 39 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
| 40 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
| 41 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 4件: 46, 51, 53, 271 💬 |
| 42 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 43 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 44 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D11603 D11603 💬 |
Leriglitazone | 020 1件: 20 💬 |
| 45 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
| 46 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
| 47 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
| 48 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
| 49 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPARG 1件: PPARG 💬 |
D11256 D11256 💬 |
Seladelpar | 093 2件: 93, 94 💬 |
| 50 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
| 51 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
| 52 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 53 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
| 54 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 222 1件: 222 💬 |
| 55 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
| 56 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
SYK 1件: SYK 💬 |
D09347 D09347 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 |
| 57 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TGFB1 2件: TGFB1, TGFB2 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 |
| 58 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
| 59 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 |
| 60 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬 |
| 61 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 |
| 62 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
| 63 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 |
| 64 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 1件: 46 💬 |
| 65 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 1件: 46 💬 |
| 66 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
| 67 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
| 68 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNFSF11 1件: TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 7件: 46, 50, 93, 95, 96, 274, 299 💬 |
| 69 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TYK2 1件: TYK2 💬 |
D11817 D11817 💬 |
Deucravacitinib | 096 2件: 96, 97 💬 |