Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD40 1件: CD40 💬 |
D11357 D11357 💬 |
Bleselumab | 222 1件: 222 💬 |
2 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD40 1件: CD40 💬 |
D11610 D11610 💬 |
Iscalimab | 049 2件: 49, 53 💬 |
3 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD40 1件: CD40 💬 |
D11597 D11597 💬 |
Ravagalimab | 053 2件: 53, 97 💬 |
4 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD40LG 1件: CD40LG 💬 |
D06193 D06193 💬 |
Toralizumab | 063 1件: 63 💬 |
5 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
6 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 1件: 46 💬 |
7 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CXCR4 1件: CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 6件: 19, 20, 51, 65, 285, 299 💬 |
8 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
HLA-DMA 14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 |
D04318 D04318 💬 |
Glatiramer | 002 4件: 2 , 13, 96, 156 💬 |
9 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL10 2件: IL10, IL6 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
10 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL4 1件: IL4 💬 |
D03117 D03117 💬 |
Binetrakin | 046 1件: 46 💬 |
11 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL5 1件: IL5 💬 |
D04923 D04923 💬 |
Mepolizumab | 044 4件: 44, 45, 98, 162 💬 |
12 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL5 1件: IL5 💬 |
D08985 D08985 💬 |
Reslizumab | 044 2件: 44, 98 💬 |
13 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL6 1件: IL6 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬 |
14 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL6 1件: IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 2件: 28, 331 💬 |
15 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
16 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 1件: 13 💬 |
17 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
18 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
ITGA4 2件: ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 2件: 96, 97 💬 |
19 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
ITGA4 2件: ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 3件: 94, 96, 97 💬 |
20 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
ITGB7 1件: ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 2件: 96, 97 💬 |
21 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TGFB1 1件: TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 |
22 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFRSF13C 1件: TNFRSF13C 💬 |
D12151 D12151 💬 |
Ianalumab | 035 5件: 35, 46, 49, 53, 95 💬 |
23 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFRSF17 1件: TNFRSF17 💬 |
D11595 D11595 💬 |
Belantamab mafodotin | 028 1件: 28 💬 |
24 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFSF13 2件: TNFSF13, TNFSF13B 💬 |
D09704 D09704 💬 |
Atacicept | 013 4件: 13, 46, 49, 66 💬 |
25 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFSF13B 1件: TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬 |
26 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFSF13B 1件: TNFSF13B 💬 |
D10083 D10083 💬 |
Tabalumab | 046 2件: 46, 49 💬 |
27 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
TNFSF13B 1件: TNFSF13B 💬 |
D11127 D11127 💬 |
Tibulizumab | 053 1件: 53 💬 |