Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Intestinal immune network for IgA production 💬
1件: CD40 💬 D11357 💬 Bleselumab 1件: 222 💬
2 Intestinal immune network for IgA production 💬
1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
3 Intestinal immune network for IgA production 💬
1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
4 Intestinal immune network for IgA production 💬
1件: CD40LG 💬 D06193 💬 Toralizumab 1件: 63 💬
5 Intestinal immune network for IgA production 💬
2件: CD80, CD86 💬 D03203 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
6 Intestinal immune network for IgA production 💬
2件: CD80, CD86 💬 D03222 💬 Belatacept 1件: 46 💬
7 Intestinal immune network for IgA production 💬
1件: CXCR4 💬 D08971 💬 Plerixafor 6件: 19, 20, 51, 65, 285, 299 💬
8 Intestinal immune network for IgA production 💬
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
9 Intestinal immune network for IgA production 💬
2件: IL10, IL6 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
10 Intestinal immune network for IgA production 💬
1件: IL4 💬 D03117 💬 Binetrakin 1件: 46 💬
11 Intestinal immune network for IgA production 💬
1件: IL5 💬 D04923 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
12 Intestinal immune network for IgA production 💬
1件: IL5 💬 D08985 💬 Reslizumab 2件: 44, 98 💬
13 Intestinal immune network for IgA production 💬
1件: IL6 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
14 Intestinal immune network for IgA production 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
15 Intestinal immune network for IgA production 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
16 Intestinal immune network for IgA production 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
17 Intestinal immune network for IgA production 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
18 Intestinal immune network for IgA production 💬
2件: ITGA4, ITGB7 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
19 Intestinal immune network for IgA production 💬
2件: ITGA4, ITGB7 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
20 Intestinal immune network for IgA production 💬
1件: ITGB7 💬 D09901 💬 Etrolizumab 2件: 96, 97 💬
21 Intestinal immune network for IgA production 💬
1件: TGFB1 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
22 Intestinal immune network for IgA production 💬
1件: TNFRSF13C 💬 D12151 💬 Ianalumab 5件: 35, 46, 49, 53, 95 💬
23 Intestinal immune network for IgA production 💬
1件: TNFRSF17 💬 D11595 💬 Belantamab mafodotin 1件: 28 💬
24 Intestinal immune network for IgA production 💬
2件: TNFSF13, TNFSF13B 💬 D09704 💬 Atacicept 4件: 13, 46, 49, 66 💬
25 Intestinal immune network for IgA production 💬
1件: TNFSF13B 💬 D03068 💬 Belimumab 12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300 💬
26 Intestinal immune network for IgA production 💬
1件: TNFSF13B 💬 D10083 💬 Tabalumab 2件: 46, 49 💬
27 Intestinal immune network for IgA production 💬
1件: TNFSF13B 💬 D11127 💬 Tibulizumab 1件: 53 💬