Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00664 D00664 💬 |
Cetirizine | 013 4件: 13, 28, 35, 300 💬 |
2 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07662 D07662 💬 |
Cetirizine | 013 4件: 13, 28, 35, 300 💬 |
3 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00665 D00665 💬 |
Chlorpheniramine | 014 1件: 14 💬 |
4 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00668 D00668 💬 |
Chlorpheniramine | 014 1件: 14 💬 |
5 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07398 D07398 💬 |
Chlorpheniramine | 014 1件: 14 💬 |
6 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07803 D07803 💬 |
Chlorpheniramine | 014 1件: 14 💬 |
7 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00666 D00666 💬 |
Clemastine | 013 1件: 13 💬 |
8 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D03535 D03535 💬 |
Clemastine | 013 1件: 13 💬 |
9 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D03693 D03693 💬 |
Desloratadine | 013 1件: 13 💬 |
10 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07803 D07803 💬 |
Dexchlorpheniramine | 013 2件: 13, 49 💬 |
11 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00300 D00300 💬 |
Diphenhydramine | 011 10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
12 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00669 D00669 💬 |
Diphenhydramine | 011 10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
13 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D02419 D02419 💬 |
Diphenhydramine | 011 10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
14 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D03285 D03285 💬 |
Diphenhydramine | 011 10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
15 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D03360 D03360 💬 |
Diphenhydramine | 011 10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
16 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D03854 D03854 💬 |
Diphenhydramine | 011 10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300 💬 |
17 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D01172 D01172 💬 |
Diphenylpyraline | 098 1件: 98 💬 |
18 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D01627 D01627 💬 |
Diphenylpyraline | 098 1件: 98 💬 |
19 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07862 D07862 💬 |
Diphenylpyraline | 098 1件: 98 💬 |
20 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00814 D00814 💬 |
Doxepin | 006 1件: 6 💬 |
21 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07875 D07875 💬 |
Doxepin | 006 1件: 6 💬 |
22 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00671 D00671 💬 |
Fexofenadine | 013 2件: 13, 46 💬 |
23 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07958 D07958 💬 |
Fexofenadine | 013 2件: 13, 46 💬 |
24 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D08040 D08040 💬 |
Histamine | 013 1件: 13 💬 |
25 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07402 D07402 💬 |
Levocetirizine | 061 1件: 61 💬 |
26 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00364 D00364 💬 |
Loratadine | 013 4件: 13, 46, 89, 98 💬 |
27 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00480 D00480 💬 |
Promethazine | 096 1件: 96 💬 |
28 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D00494 D00494 💬 |
Promethazine | 096 1件: 96 💬 |
29 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D01242 D01242 💬 |
Promethazine | 096 1件: 96 💬 |
30 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D03290 D03290 💬 |
Promethazine | 096 1件: 96 💬 |
31 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 1件: HRH1 💬 |
D07407 D07407 💬 |
Rupatadine | 046 1件: 46 💬 |
32 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 1件: 254 💬 |
33 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00789 D00789 💬 |
Chlorpromazine | 254 1件: 254 💬 |
34 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D03274 D03274 💬 |
Chlorpromazine | 254 1件: 254 💬 |
35 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D04034 D04034 💬 |
Chlorpromazine | 254 1件: 254 💬 |
36 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D00454 D00454 💬 |
Olanzapine | 002 2件: 2 , 8 💬 |
37 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HRH1 4件: HRH1, HTR2A, HTR2B, HTR2C 💬 |
D06623 D06623 💬 |
Olanzapine | 002 2件: 2 , 8 💬 |
38 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 2件: 6 , 206 💬 |
39 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
40 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D00274 D00274 💬 |
Cisapride | 013 1件: 13 💬 |
41 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D02092 D02092 💬 |
Cisapride | 013 1件: 13 💬 |
42 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D09645 D09645 💬 |
Nelotanserin | 006 1件: 6 💬 |
43 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D00458 D00458 💬 |
Quetiapine | 006 2件: 6 , 13 💬 |
44 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D08456 D08456 💬 |
Quetiapine | 006 2件: 6 , 13 💬 |
45 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D00426 D00426 💬 |
Risperidone | 008 5件: 8 , 156, 179, 187, 206 💬 |
46 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 4件: 140, 144, 145, 149 💬 |
47 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D00820 D00820 💬 |
Trazodone | 002 1件: 2 💬 |
48 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 3件: HTR2A, HTR2B, HTR2C 💬 |
D08626 D08626 💬 |
Trazodone | 002 1件: 2 💬 |
49 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2A 2件: HTR2A, HTR2C 💬 |
D00283 D00283 💬 |
Clozapine | 006 1件: 6 💬 |
50 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
HTR2C 1件: HTR2C 💬 |
D02578 D02578 💬 |
Agomelatine | 006 1件: 6 💬 |
51 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
52 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
53 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
54 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
55 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
56 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
57 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
58 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
NGF 1件: NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 2件: 226, 298 💬 |
59 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
60 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
61 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
PRKCD 4件: PRKCD, PRKCE, PRKCH, PRKCQ 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 1件: 97 💬 |
62 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
PTGER2 2件: PTGER2, PTGER4 💬 |
D00419 D00419 💬 |
Misoprostol | 046 3件: 46, 70, 271 💬 |
63 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
SRC 1件: SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 2件: 2 , 67 💬 |
64 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
SRC 1件: SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
65 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
SRC 1件: SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
66 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
SRC 1件: SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 3件: 6 , 89, 272 💬 |
67 | Inflammatory mediator regulation of TRP channels 💬 Related to 22 target genes, 42 drugs (DrugBank) and 58 diseases in DDrare |
TRPV1 1件: TRPV1 💬 |
D00250 D00250 💬 |
Capsaicin | 002 5件: 2 , 6 , 19, 86, 226 💬 |