Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00150 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
2 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D02014 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
3 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00522 💬 Candesartan 2件: 58, 67 💬
4 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00522 💬 Candesartan cilexetil 1件: 67 💬
5 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00626 💬 Candesartan cilexetil 1件: 67 💬
6 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00523 💬 Irbesartan 4件: 66, 167, 168, 222 💬
7 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
8 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
9 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D11776 💬 Sparsentan 3件: 66, 218, 222 💬
10 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00627 💬 Telmisartan 2件: 66, 67 💬
11 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00400 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬
12 Aldosterone synthesis and secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin 1件: 299 💬
13 Aldosterone synthesis and secretion 💬
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin 3件:  8 , 46, 210 💬
14 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
15 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
16 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
17 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine 1件: 67 💬
18 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
19 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
20 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
21 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine 1件:  6  💬
22 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
23 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
24 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
25 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine 1件: 90 💬
26 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
27 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
28 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine 1件: 226 💬
29 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
30 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
31 Aldosterone synthesis and secretion 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
32 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
33 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
34 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid 17件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
35 Aldosterone synthesis and secretion 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D00538 💬 Zonisamide 1件:  6  💬
36 Aldosterone synthesis and secretion 💬
1件: CYP11B2 💬 D11061 💬 Osilodrostat 1件: 75 💬
37 Aldosterone synthesis and secretion 💬
1件: KCNJ5 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
38 Aldosterone synthesis and secretion 💬
1件: KCNJ5 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
39 Aldosterone synthesis and secretion 💬
1件: MC2R 💬 D00146 💬 Corticotropin 15件:  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
40 Aldosterone synthesis and secretion 💬
1件: MC2R 💬 D00284 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
41 Aldosterone synthesis and secretion 💬
1件: NPR1 💬 D04051 💬 Erythrityl tetranitrate 1件: 46 💬
42 Aldosterone synthesis and secretion 💬
1件: NPR1 💬 D05147 💬 Nesiritide 2件: 46, 58 💬
43 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D00227 💬 Aminophylline 1件: 63 💬
44 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D05429 💬 Aminophylline 1件: 63 💬
45 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D07546 💬 Bucladesine 1件: 246 💬
46 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
47 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
48 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D00718 💬 Flavoxate 1件: 226 💬
49 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D07961 💬 Flavoxate 1件: 226 💬
50 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D00371 💬 Theophylline 2件: 236, 299 💬
51 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D01712 💬 Theophylline 2件: 236, 299 💬
52 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D02017 💬 Theophylline 2件: 236, 299 💬
53 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D06103 💬 Theophylline 2件: 236, 299 💬
54 Aldosterone synthesis and secretion 💬
1件: PDE2A 💬 D06104 💬 Theophylline 2件: 236, 299 💬
55 Aldosterone synthesis and secretion 💬
1件: PRKCE 💬 D09671 💬 Sotrastaurin 1件: 97 💬