Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00615 D00615 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
2 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02914 D02914 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
3 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 4件: 13, 51, 67, 298 💬 |
4 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 1件: 67 💬 |
5 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00616 D00616 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
6 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D03830 D03830 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
7 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 3件: 51, 58, 86 💬 |
8 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 1件: 6 💬 |
9 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00617 D00617 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
10 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 2件: 70, 86 💬 |
11 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 2件: 50, 81 💬 |
12 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 1件: 90 💬 |
13 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D05442 D05442 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
14 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 2件: 58, 272 💬 |
15 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 1件: 226 💬 |
16 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
17 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00619 D00619 💬 |
Verapamil | 096 3件: 96, 140, 167 💬 |
18 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 096 3件: 96, 140, 167 💬 |
19 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D01303 D01303 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
20 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D07971 D07971 💬 |
Flunarizine | 058 4件: 58, 86, 149, 215 💬 |
21 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00399 D00399 💬 |
Valproic acid | 002 17件: 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬 |
22 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬 |
D00538 D00538 💬 |
Zonisamide | 006 1件: 6 💬 |
23 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00962 D00962 💬 |
Clomifene | 074 1件: 74 💬 |
24 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D07726 D07726 💬 |
Clomifene | 074 1件: 74 💬 |
25 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D11513 D11513 💬 |
Estetrol | 053 1件: 53 💬 |
26 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D11514 D11514 💬 |
Estetrol | 053 1件: 53 💬 |
27 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00105 D00105 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
28 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01413 D01413 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
29 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01617 D01617 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
30 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01953 D01953 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
31 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D04061 D04061 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
32 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D04063 D04063 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
33 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D04064 D04064 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
34 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D04065 D04065 💬 |
Estradiol | 013 7件: 13, 46, 49, 65, 76, 226, 299 💬 |
35 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01413 D01413 💬 |
Estradiol valerate | 065 1件: 65 💬 |
36 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00185 D00185 💬 |
Estriol | 013 2件: 13, 227 💬 |
37 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01986 D01986 💬 |
Estriol | 013 2件: 13, 227 💬 |
38 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D01161 D01161 💬 |
Fulvestrant | 049 2件: 49, 86 💬 |
39 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00575 D00575 💬 |
Mestranol | 046 2件: 46, 49 💬 |
40 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D08409 D08409 💬 |
Prasterone | 049 6件: 49, 53, 83, 86, 96, 113 💬 |
41 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D02217 D02217 💬 |
Raloxifene | 046 1件: 46 💬 |
42 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D08465 D08465 💬 |
Raloxifene | 046 1件: 46 💬 |
43 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D00966 D00966 💬 |
Tamoxifen | 002 4件: 2 , 86, 113, 227 💬 |
44 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
ESR2 1件: ESR2 💬 |
D08559 D08559 💬 |
Tamoxifen | 002 4件: 2 , 86, 113, 227 💬 |
45 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D09791 D09791 💬 |
Arbaclofen | 013 2件: 13, 206 💬 |
46 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D08861 D08861 💬 |
Arbaclofen Placarbil | 013 1件: 13 💬 |
47 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABBR1 2件: GABBR1, GABBR2 💬 |
D00241 D00241 💬 |
Baclofen | 002 7件: 2 , 10, 13, 18, 65, 149, 206 💬 |
48 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
KCNJ11 1件: KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 2件: 13, 193 💬 |
49 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
KCNJ11 1件: KCNJ11 💬 |
D00418 D00418 💬 |
Minoxidil | 179 1件: 179 💬 |
50 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
KCNJ11 1件: KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 3件: 6 , 21, 299 💬 |
51 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
KCNJ11 3件: KCNJ11, KCNJ3, KCNJ5 💬 |
D00636 D00636 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
52 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
KCNJ11 3件: KCNJ11, KCNJ3, KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 2件: 28, 127 💬 |
53 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
54 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
55 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
56 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
57 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
58 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
59 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
60 | GnRH secretion 💬 Related to 19 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
RAF1 1件: RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |