Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Parkinson disease 💬
1件: ADORA2A 💬 D00045 💬 Adenosine 3件: 13, 58, 65 💬
2 Parkinson disease 💬
1件: ADORA2A 💬 D02769 💬 Adenosine phosphate 1件: 46 💬
3 Parkinson disease 💬
1件: ADORA2A 💬 D00528 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
4 Parkinson disease 💬
1件: ADORA2A 💬 D01453 💬 Caffeine 9件:  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
5 Parkinson disease 💬
1件: ADORA2A 💬 D04641 💬 Istradefylline 1件:  6  💬
6 Parkinson disease 💬
1件: ADORA2A 💬 D09717 💬 Preladenant 1件:  6  💬
7 Parkinson disease 💬
1件: ADORA2A 💬 D05711 💬 Regadenoson 1件: 58 💬
8 Parkinson disease 💬
1件: ADORA2A 💬 D02017 💬 Theophylline 2件: 236, 299 💬
9 Parkinson disease 💬
1件: ADORA2A 💬 D10174 💬 Tozadenant 1件:  6  💬
10 Parkinson disease 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
11 Parkinson disease 💬
1件: DRD1 💬 D11431 💬 Tavapadon 1件:  6  💬
12 Parkinson disease 💬
2件: DRD1, DRD2 💬 D02004 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
13 Parkinson disease 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
14 Parkinson disease 💬
2件: DRD1, DRD2 💬 D09886 💬 Dexpramipexole 1件:  2  💬
15 Parkinson disease 💬
2件: DRD1, DRD2 💬 D00633 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
16 Parkinson disease 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
17 Parkinson disease 💬
2件: DRD1, DRD2 💬 D01044 💬 Flupentixol 1件: 97 💬
18 Parkinson disease 💬
2件: DRD1, DRD2 💬 D11839 💬 Foslevodopa 1件:  6  💬
19 Parkinson disease 💬
2件: DRD1, DRD2 💬 D00059 💬 Levodopa 8件:  2 ,  4 ,  6 , 17, 90, 140, 164, 201 💬
20 Parkinson disease 💬
2件: DRD1, DRD2 💬 D00502 💬 Pergolide 1件:  6  💬
21 Parkinson disease 💬
2件: DRD1, DRD2 💬 D08339 💬 Pergolide 1件:  6  💬
22 Parkinson disease 💬
1件: DRD2 💬 D01164 💬 Aripiprazole 2件:  6 , 206 💬
23 Parkinson disease 💬
1件: DRD2 💬 D00780 💬 Bromocriptine 2件:  6 , 74 💬
24 Parkinson disease 💬
1件: DRD2 💬 D03165 💬 Bromocriptine 2件:  6 , 74 💬
25 Parkinson disease 💬
1件: DRD2 💬 D00702 💬 Buspirone 3件:  6 , 51, 179 💬
26 Parkinson disease 💬
1件: DRD2 💬 D07593 💬 Buspirone 3件:  6 , 51, 179 💬
27 Parkinson disease 💬
1件: DRD2 💬 D00987 💬 Cabergoline 3件:  6 , 74, 75 💬
28 Parkinson disease 💬
1件: DRD2 💬 D09997 💬 Cariprazine 1件: 21 💬
29 Parkinson disease 💬
1件: DRD2 💬 D00270 💬 Chlorpromazine 1件: 254 💬
30 Parkinson disease 💬
1件: DRD2 💬 D00789 💬 Chlorpromazine 1件: 254 💬
31 Parkinson disease 💬
1件: DRD2 💬 D03274 💬 Chlorpromazine 1件: 254 💬
32 Parkinson disease 💬
1件: DRD2 💬 D04034 💬 Chlorpromazine 1件: 254 💬
33 Parkinson disease 💬
1件: DRD2 💬 D01745 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
34 Parkinson disease 💬
1件: DRD2 💬 D07868 💬 Domperidone 5件:  6 , 13, 17, 51, 230 💬
35 Parkinson disease 💬
1件: DRD2 💬 D00136 💬 Haloperidol 1件:  8  💬
36 Parkinson disease 💬
1件: DRD2 💬 D01898 💬 Haloperidol 1件:  8  💬
37 Parkinson disease 💬
1件: DRD2 💬 D01462 💬 Lisuride 2件:  6 , 86 💬
38 Parkinson disease 💬
1件: DRD2 💬 D08132 💬 Lisuride 2件:  6 , 86 💬
39 Parkinson disease 💬
1件: DRD2 💬 D07309 💬 Melperone 1件:  6  💬
40 Parkinson disease 💬
1件: DRD2 💬 D00726 💬 Metoclopramide 1件: 51 💬
41 Parkinson disease 💬
1件: DRD2 💬 D02213 💬 Metoclopramide 1件: 51 💬
42 Parkinson disease 💬
1件: DRD2 💬 D05008 💬 Metoclopramide 1件: 51 💬
43 Parkinson disease 💬
1件: DRD2 💬 D00454 💬 Olanzapine 2件:  2 ,  8  💬
44 Parkinson disease 💬
1件: DRD2 💬 D06623 💬 Olanzapine 2件:  2 ,  8  💬
45 Parkinson disease 💬
1件: DRD2 💬 D09397 💬 Pardoprunox 1件:  6  💬
46 Parkinson disease 💬
1件: DRD2 💬 D00560 💬 Pimozide 1件:  2  💬
47 Parkinson disease 💬
1件: DRD2 💬 D07305 💬 Piribedil 1件:  6  💬
48 Parkinson disease 💬
1件: DRD2 💬 D00559 💬 Pramipexole 3件:  2 ,  6 , 20 💬
49 Parkinson disease 💬
1件: DRD2 💬 D05575 💬 Pramipexole 3件:  2 ,  6 , 20 💬
50 Parkinson disease 💬
1件: DRD2 💬 D09953 💬 Pridopidine 3件:  2 ,  6 ,  8  💬
51 Parkinson disease 💬
1件: DRD2 💬 D00458 💬 Quetiapine 2件:  6 , 13 💬
52 Parkinson disease 💬
1件: DRD2 💬 D08456 💬 Quetiapine 2件:  6 , 13 💬
53 Parkinson disease 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
54 Parkinson disease 💬
1件: DRD2 💬 D00784 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬
55 Parkinson disease 💬
1件: DRD2 💬 D08489 💬 Ropinirole 4件:  2 ,  6 , 74, 309 💬
56 Parkinson disease 💬
1件: DRD2 💬 D05768 💬 Rotigotine 2件:  6 , 127 💬
57 Parkinson disease 💬
1件: DRD2 💬 D01226 💬 Sulpiride 5件:  2 ,  6 , 17, 46, 70 💬
58 Parkinson disease 💬
1件: DRD2 💬 D08549 💬 Sulpiride 5件:  2 ,  6 , 17, 46, 70 💬
59 Parkinson disease 💬
1件: DRD2 💬 D01348 💬 Terguride 2件: 51, 86 💬
60 Parkinson disease 💬
1件: DRD2 💬 D08590 💬 Tiapride 1件:  8  💬
61 Parkinson disease 💬
1件: DRD2 💬 D00799 💬 Trifluoperazine 2件: 283, 284 💬
62 Parkinson disease 💬
1件: DRD2 💬 D01448 💬 Trifluoperazine 2件: 283, 284 💬
63 Parkinson disease 💬
1件: DRD2 💬 D08636 💬 Trifluoperazine 2件: 283, 284 💬
64 Parkinson disease 💬
1件: KEAP1 💬 D03846 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬
65 Parkinson disease 💬
1件: MAOA 💬 D02561 💬 Moclobemide 1件:  6  💬
66 Parkinson disease 💬
2件: MAOA, MAOB 💬 D02579 💬 Iproniazid 1件:  6  💬
67 Parkinson disease 💬
2件: MAOA, MAOB 💬 D00505 💬 Phenelzine 1件:  6  💬
68 Parkinson disease 💬
2件: MAOA, MAOB 💬 D08349 💬 Phenelzine 1件:  6  💬
69 Parkinson disease 💬
3件: MAOA, MAOB, SLC6A3 💬 D05458 💬 Phentermine 1件: 97 💬
70 Parkinson disease 💬
3件: MAOA, MAOB, SLC6A3 💬 D05459 💬 Phentermine 1件: 97 💬
71 Parkinson disease 💬
1件: MAOB 💬 D02562 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
72 Parkinson disease 💬
1件: MAOB 💬 D08469 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
73 Parkinson disease 💬
1件: MAOB 💬 D10829 💬 Rasagiline 7件:  2 ,  5 ,  6 , 13, 17, 58, 66 💬
74 Parkinson disease 💬
1件: MAOB 💬 D10158 💬 Safinamide 2件:  6 , 17 💬
75 Parkinson disease 💬
1件: MAOB 💬 D00785 💬 Selegiline 1件:  6  💬
76 Parkinson disease 💬
1件: MAOB 💬 D03731 💬 Selegiline 1件:  6  💬
77 Parkinson disease 💬
1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
78 Parkinson disease 💬
1件: MAPT 💬 D11210 💬 Flortaucipir 3件:  5 ,  7 , 127 💬
79 Parkinson disease 💬
1件: MAPT 💬 D11293 💬 Gosuranemab 1件:  5  💬
80 Parkinson disease 💬
1件: NFE2L2 💬 D10964 💬 Omaveloxolone 1件: 18 💬
81 Parkinson disease 💬
1件: PSMB5 💬 D03150 💬 Bortezomib 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬
82 Parkinson disease 💬
1件: PSMB5 💬 D08880 💬 Carfilzomib 1件: 28 💬
83 Parkinson disease 💬
1件: PSMB5 💬 D10130 💬 Ixazomib 5件: 13, 16, 28, 51, 61 💬
84 Parkinson disease 💬
1件: SLC18A2 💬 D10701 💬 Deutetrabenazine 1件:  8  💬
85 Parkinson disease 💬
1件: SLC18A2 💬 D08575 💬 Tetrabenazine 1件:  8  💬
86 Parkinson disease 💬
1件: SLC18A2 💬 D10675 💬 Valbenazine 1件:  8  💬
87 Parkinson disease 💬
1件: SLC6A3 💬 D03215 💬 Armodafinil 3件:  6 , 13, 84 💬
88 Parkinson disease 💬
1件: SLC6A3 💬 D00817 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
89 Parkinson disease 💬
1件: SLC6A3 💬 D07591 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
90 Parkinson disease 💬
1件: SLC6A3 💬 D07938 💬 Bupropion 5件:  8 , 18, 21, 96, 171 💬
91 Parkinson disease 💬
1件: SLC6A3 💬 D08130 💬 Lisdexamfetamine 1件: 13 💬
92 Parkinson disease 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
93 Parkinson disease 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
94 Parkinson disease 💬
1件: SNCA 💬 D11420 💬 Prasinezumab 1件:  6  💬
95 Parkinson disease 💬
1件: SOD1 💬 D11811 💬 Tofersen 1件:  2  💬
96 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D11595 💬 Belantamab mafodotin 1件: 28 💬
97 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D09587 💬 Brentuximab vedotin 2件: 49, 51 💬
98 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00570 💬 Colchicine 7件:  2 , 42, 46, 56, 93, 210, 266 💬
99 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D00491 💬 Paclitaxel 2件: 46, 85 💬
100 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D05333 💬 Paclitaxel 2件: 46, 85 💬
101 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D01068 💬 Vinblastine 2件: 34, 65 💬
102 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08675 💬 Vinblastine 2件: 34, 65 💬
103 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D02197 💬 Vincristine 4件: 26, 34, 65, 331 💬
104 Parkinson disease 💬
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 D08679 💬 Vincristine 4件: 26, 34, 65, 331 💬