Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Spinocerebellar ataxia 💬
 3件: GRIA1, GRIA2, GRIA3 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
2 Spinocerebellar ataxia 💬
 3件: GRIA1, GRIA2, GRIA3 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
3 Spinocerebellar ataxia 💬
 3件: GRIA1, GRIA2, GRIA3 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
4 Spinocerebellar ataxia 💬
 8件: GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
5 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate 2件:  6 , 206 💬
6 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
7 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
8 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
9 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
10 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
11 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
12 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
13 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
14 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
15 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
16 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
17 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
18 Spinocerebellar ataxia 💬
 2件: KCNC3, KCND3 💬 D10228 💬 Amifampridine 3件:  3 , 11, 12 💬
19 Spinocerebellar ataxia 💬
 2件: KCNC3, KCND3 💬 D04127 💬 Dalfampridine 5件:  3 ,  4 ,  6 , 13, 14 💬
20 Spinocerebellar ataxia 💬
 1件: KCND3 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
21 Spinocerebellar ataxia 💬
 1件: KCND3 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
22 Spinocerebellar ataxia 💬
 1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
23 Spinocerebellar ataxia 💬
 1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
24 Spinocerebellar ataxia 💬
 1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
25 Spinocerebellar ataxia 💬
 1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
26 Spinocerebellar ataxia 💬
 3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
27 Spinocerebellar ataxia 💬
 1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
28 Spinocerebellar ataxia 💬
 1件: PSMB5 💬 D03150 💬 Bortezomib 16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331 💬
29 Spinocerebellar ataxia 💬
 1件: PSMB5 💬 D08880 💬 Carfilzomib 1件: 28 💬
30 Spinocerebellar ataxia 💬
 1件: PSMB5 💬 D10130 💬 Ixazomib 5件: 13, 16, 28, 51, 61 💬