Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
2 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D06272 D06272 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
3 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
4 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
CDK4 2件: CDK4, CDK6 💬 |
D10688 D10688 💬 |
Abemaciclib | 034 1件: 34 💬 |
5 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 034 5件: 34, 51, 86, 89, 331 💬 |
6 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04023 D04023 💬 |
Erlotinib | 094 1件: 94 💬 |
7 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
8 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
9 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
10 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D04024 D04024 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
11 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
12 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
13 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
14 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 1件: 232 💬 |
15 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
16 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
17 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
IGF1R 1件: IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 1件: 51 💬 |
18 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
KEAP1 1件: KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬 |
19 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
20 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
21 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
22 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
23 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MET 1件: MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
24 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D02714 D02714 💬 |
Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 |
25 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 41件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
26 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D06068 D06068 💬 |
Temsirolimus | 013 4件: 13, 34, 89, 331 💬 |
27 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
28 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
29 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
30 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 13件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬 |
31 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
32 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
33 | Hepatocellular carcinoma 💬 Related to 20 target genes, 27 drugs (DrugBank) and 59 diseases in DDrare |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 4件: 51, 85, 222, 274 💬 |