Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ACOMPLIA 20 mg film-coated tablets[1] Rimonabant[1] D05731 [1] CNR1 💬[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 193
2Actonel Once a Week 35 mg film-coated tablets[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
3Actonel/Optinate 5mg film-coated tablets[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
4ADCIRCA 20 mg film-coated tablets[1] Tadalafil[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
5Adempas® 0.5 mg film-coated tablets[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
6Adempas® 1.0 mg film-coated tablets[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
7Adempas® 1.5 mg film-coated tablets[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
8Adempas® 2.0 mg film-coated tablets[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
9Adempas® 2.5 mg film-coated tablets[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
10Ambrisentan 5 mg film-coated tablets[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
11Ambrisentan 5mg film-coated tablets [marketed product][1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
12Aubagio 14 mg film-coated tablets[1] Teriflunomide[1] D10172 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[1] 13
13Azithromycin 500 mg film-coated tablet[1] Azithromycin[3] D02134 ,
D06390 ,
D07486 		--[1] 299
14CellCept 500 mg film-coated tablets[1] Mycophenolate mofetil[3] D00752 ,
D05094 ,
D05095 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 11
15Cialis 10 mg film-coated tablets[1] Tadalafil[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 86, 113
16Cialis 2.5 mg film-coated tablets[1] Tadalafil[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 86, 113
17Cialis 20 mg film-coated tablets[1] Tadalafil[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 86, 113
18Cialis 5 mg film-coated tablets[1] Tadalafil[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 86, 113
19Crestor Film-Coated Tablet[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79
20Crestor Tablets (calcium rosuvastatin) Film-Coated tablets[2] Calcium,
Rosuvastatin		[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79
21Cuprior 150 mg film-coated tablets[1] Triethylenetetramine---[1] 171
22Cuprior 150mg film-coated tablets[1] Triethylenetetramine---[1] 171
23Doptelet 20 mg film-coated tablets[1] Avatrombopag[1] D10306 [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 63
24Film-coated tablet----[1] 97
25Fostamatinib 50 mg blue film-coated tablet[1] Fostamatinib[1] D09347 [1] SYK 💬[17] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease - COVID-19, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[1] 46
26Glentek 50 mg film-coated tablets----[1] 18
27GLPG3970 film-coated tablet----[1] 49
28Idebenone 150 mg film-coated tablets[1] Idebenone[1] D01750 --[1] 113
29JNJ-38518168-ZBQ - film-coated tablet - 10 mg----[1] 46
30JNJ-38518168-ZBQ - film-coated tablet - 10mg----[1] 46
31JNJ-38518168-ZBQ - film-coated tablet - 3 mg----[1] 46
32JNJ-38518168-ZBQ - film-coated tablet - 30 mg----[1] 46
33JNJ-38518168-ZBQ - film-coated tablet - 30mg----[1] 46
34JNJ-38518168-ZBQ - film-coated tablet - 3mg----[1] 46
35Jyseleca 100 mg film-coated tablets[1] Filgotinib[1] D10871 [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
36Jyseleca 200 mg film-coated tablets[1] Filgotinib[1] D10871 [1] JAK1 💬[27] Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
37Kalydeco 150 mg film-coated tablets[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
38Mayzent 2 mg film-coated tablets[1] Siponimod[1] D11460 [2] S1PR1,
S1PR5 💬		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 13
39Minocycline 100 mg Film-coated Tablets[1] Minocycline[2] D00850 ,
D05045 		--[1] 13
40Norvir 100 mg film-coated tablets----[1] 299
41Ondansetron 8 mg film-coated tablets[1] Ondansetron[2] D00456 ,
D00678 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[1] 6
42Orkambi 100 mg/125 mg film-coated tablets[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
43Orkambi 200 mg/125 mg film-coated tablets[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
44Revatio 20 mg film-coated tablets----[1] 86
45Revatio ® 20 mg film-coated tablets[1] Sildenafil[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
46Revolade 25 mg film-coated tablets[1] Eltrombopag---[1] 63
47Revolade 50 mg film-coated tablets[1] Eltrombopag---[1] 63
48Rilutek 50 mg film-coated tablets[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[1] 2
49RILUTEK 50 mg, film-coated tablets[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[1] 2
50Simvastatin 40 mg film-coated tablets[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 13
51Sivatin 40 mg film-coated tablets----[1] 13
52Symkevi 100mg/150mg Film-coated tablets[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
53Tadalafil 20 mg film-coated tablets[1] Tadalafil[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
54Ursofalk® 500 mg film-coated tablets[1] Ursodeoxycholic acid[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[1] 93
55XELJANZ 5 mg film-coated tablets[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 97
56Xeljanz 5mg film-coated tablets[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 97