Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Acthar low dose (40 U)[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
2Administration of a low dose of desipramine[1] Desipramine[2] D00812 ,
D07791 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 156
3Ambrisentan - low dose[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
4AXO-AAV-GM2 Low Dose----[1] 19
5BI 655064 low dose----[1] 46
6BIIL 284 BS low dose----[1] 46
7BIIL 284 BS, low dose----[1] 299
8BIIL 284 BS, low dose, adult patients----[1] 299
9BIIL 284 BS, low dose, pediatric patients----[1] 299
10BIRB 796 BS, low dose----[1] 46
11BLI-1300 low dose----[1] 96
12Brazikumab low dose[1] Brazikumab[1] D10912 [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 96
13Clobazam Low Dose[1] Clobazam[1] D01253 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144
14CVN424 Low Dose----[1] 6
15CVT-301 Low Dose----[1] 6
16Cyclosporin, low dose steroid[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 222
17Elamipretide (low dose)[1] Elamipretide[1] D10925 --[1] 21
18EUR-1008 (APT-1008) Low Dose----[1] 298
19Fentanyl (Low Dose)[1] Fentanyl[2] D00320 ,
D01399 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 215
20Fentanyl (Low Dose) + Dexmedetomidine[2] Dexmedetomidine,
Fentanyl		[4] D00320 ,
D00514 ,
D01205 ,
D01399 		[4] ADRA2A,
ADRA2B,
ADRA2C,
OPRM1 💬		[4] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 215
21HMPL-004 low dose----[1] 97
22IgPro20 (low dose)----[1] 14
23Iloprost low dose[1] Iloprost[1] D02721 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 51
24KPS-0373, Low dose----[1] 18
25KW-6356 Low Dose----[1] 6
26Large dose of prednisolone plus intra-lesional of Triamcinolone Acetonide followed the systemic combination of mycophenolate mofetil (MMF), dapsone and low dose prednisolone in treatment of MMP[5] Dapsone,
Mycophenolate mofetil,
Mycophenolic acid,
Prednisolone,
Triamcinolone		[18] D00385 ,
D00472 ,
D00592 ,
D00752 ,
D00980 ,
D00981 ,
D00982 ,
D00983 ,
D00984 ,
D00985 ,
D01239 ,
D01998 ,
D02156 ,
D03301 ,
D05094 ,
D05095 ,
D05096 ,
D06216 		[3] IMPDH1,
IMPDH2,
NR3C1 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism 💬[1] 162
27LiRIS low dose and LiRIS high dose----[1] 226
28Low dose----[1] 97
29Low dose AFFITOPE® PD03A + Adjuvant----[1] 6
30Low dose arm receiving neutral oil and 400 IU/g of Vitamin D every second day[1] Vitamin D---[1] 13
31Low Dose Aspirin (162 mg/day)[1] Acetylsalicylic acid (Synonym: 81 mg Low Dose Aspirin)[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 13
32Low dose BIBF 1120 twice daily----[1] 85
33Low dose BIBF1120 once daily----[1] 85
34Low Dose Budesonide[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
35Low dose budesonide tablet[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 98
36Low dose cannabis[1] Medical Cannabis---[1] 13
37Low dose levodopa[1] Levodopa[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
38Low Dose Mesenchymal Stem Cells (MSCs)----[1] 49
39Low Dose MT-1303----[1] 97
40Low dose naltrexone[1] Naltrexone[2] D02095 ,
D05113 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 96, 97
41Low dose of BIIL 284 BS tablets----[1] 46
42Low dose ORTD-1----[1] 46
43Low dose prednisolone[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 84
44Low dose TSO----[1] 96
45Low dose vehicle control----[1] 46
46Low Dose-VIS649----[1] 66
47LX3305 low dose----[1] 46
48M5049 low dose----[1] 49
49MEDI7183 low dose----[1] 97
50MMX Mesalamine/Mesalazine (Low Dose)[1] Mesalazine[1] D00377 --[1] 97
51MT-1303 Low dose----[1] 49
52MT-7117 Low Dose----[1] 254
53MultiStem low dose[1] MultiStem---[1] 97
54Mycophenolate mofetil, low dose steroid[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 222
55OCU400 Low Dose----[1] 90
56Other: Low dose (1 mcg) ACTH stimulation test[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 193
57PF-06649751 low dose (1 mg QD)[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬		[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
58Prednisone, low dose rituximab[2] Prednisone,
Rituximab		[2] D00473 ,
D02994 		[2] MS4A1,
NR3C1 💬		[2] Hematopoietic cell lineage, Neuroactive ligand-receptor interaction 💬[1] 61
59PXT3003 Low dose----[1] 10
60Ravicti low dose[1] Glycerol phenylbutyrate[1] D10127 --[1] 299
61SA001 Low dose----[1] 53
62SEN0014196 (Low Dose)----[1] 8
63SHR1459 Low Dose----[1] 222
64TAS5315 low dose----[1] 46
65Tiotropium bromide-low dose-2.5mcg[1] Tiotropium---[1] 299
66Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)[2] Methylprednisolone,
Ursodeoxycholic acid		[7] D00407 ,
D00734 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[2] NR1H4,
NR3C1 💬		[2] Bile secretion, Neuroactive ligand-receptor interaction 💬[1] 93
67YRA-1909 low dose----[1] 46