Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
14-Aminosalicylic acid extended release granules[1] Aminosalicylic acid[1] D00162 --[1] 96
2750 mg metformin and 7.5 g L-citrulline daily p.o.
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[2] Citrulline,
Metformin (Synonym: Metformin Hydrochloride Extended-Release)		[3] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 ,
D07706 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 113
3Aceneuramic Acid Extended-Release[1] Aceneuramic acid[1] D11016 --[1] 30
4Aceneuramic acid extended-release (Ace-ER)[1] Aceneuramic acid[1] D11016 --[1] 30
5Aceneuramic Acid Extended-Release Tablets[1] Aceneuramic acid[1] D11016 --[1] 30
6ADS-5102 (extended release amantadine HCl)[1] Amantadine[2] D00777 ,
D07441 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 6
7Advagraf prolonged-release hard capsules[2] Manganese citrate (Synonym: Release),
Tacrolimus		[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 299
8ALKS 8700 Delayed Release (DR)[1] Manganese citrate (Synonym: Release)---[1] 13
9ALKS 8700 Delayed Release (DR) Capsule[1] Manganese citrate (Synonym: Release)---[1] 13
10Amantadine HCl Extended Release[1] Amantadine[2] D00777 ,
D07441 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 6
11Amantadine HCl Extended Release Capsule[1] Amantadine[2] D00777 ,
D07441 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 6
12Antioxidant plus Pregabalin
(Synonym: PREGABALIN EXTENDED RELEASE)		[1] Pregabalin (Synonym: Pregabalin Extended Release)[1] D02716 (Name: PREGABALIN EXTENDED RELEASE)[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[1] 298
13APRISO 375 mg extended-release capsules[1] Manganese citrate (Synonym: Release)---[1] 97
14Arbaclofen Extended Release Tablets[1] Arbaclofen[1] D09791 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 13
15Asacol (mesalamine) Delayed-release Tablets[1] Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)[1] D00377 --[1] 97
16Asacol Delayed Release Tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
17Asacol Delayed-Release Tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
18AZD3241 Extended release tablets 100 mg[1] Manganese citrate (Synonym: Release)---[1] 6
19AZD3241 Extended release tablets 25 mg[1] Manganese citrate (Synonym: Release)---[1] 6
20Beraprost Sodium 314d Modified Release Tablets[1] Beraprost[1] D02720 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
21Beraprost Sodium Modified Release[1] Beraprost[1] D02720 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
22Budesonide 6 mg prolonged-release capsule, hard (BUX-PVII prototype)[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
23Budesonide 6 mg prolonged-release capsules, hard (BUX-PVII prototype)[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
24Budesonide 9 mg prolonged-release capsule, hard (BUX-PVII prototype)[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
25Budesonide 9 mg prolonged-release capsules, hard (BUX-PVII prototype)[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
26Bupropion
(Synonym: BUPROPION HYDROCHLORIDE EXTENDED RELEASE)		[1] Bupropion (Synonym: Bupropion Hydrochloride Extended Release)[3] D00817 (Name: BUPROPION HYDROCHLORIDE EXTENDED RELEASE),
D07591 ,
D07938 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
27Bupropion & Citalopram
(Synonym: BUPROPION HYDROCHLORIDE EXTENDED RELEASE)		[2] Bupropion (Synonym: Bupropion Hydrochloride Extended Release),
Citalopram		[5] D00817 (Name: BUPROPION HYDROCHLORIDE EXTENDED RELEASE),
D00822 ,
D07591 ,
D07704 ,
D07938 		[3] SLC6A2,
SLC6A3,
SLC6A4 💬		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 18
28Bupropion Hydrochloride
(Synonym: BUPROPION HYDROCHLORIDE EXTENDED RELEASE)		[1] Bupropion (Synonym: Bupropion Hydrochloride Extended Release)[3] D00817 (Name: BUPROPION HYDROCHLORIDE EXTENDED RELEASE),
D07591 ,
D07938 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 171
29Bydureon 2 mg powder and solvent for prolonged-release suspension[2] Exenatide,
Manganese citrate (Synonym: Release)		[1] D04121 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6
30Carbidopa and Levodopa Controlled Release Tablets[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
31Carbidopa/Levodopa, immediate release[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
32Combination of Minocycline and MTX or MTX alone
(Synonym: MINOLIRA EXTENDED RELEASE)		[1] Minocycline (Synonym: Minolira Extended Release)[2] D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		--[1] 46
33Comparator: diclofenac
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
34Comparator: Diclofenac sodium
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
35Continuous Release Dopamine Agonists[1] Dopamine[2] D00633 ,
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
36Controlled-release levodopa / carbidopa[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
37Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)[6] Acetate,
Cortisone acetate,
Dexamethasone,
Hydrocortisone,
Prednisolone,
Prednisone		[20] D00088 ,
D00292 ,
D00472 ,
D00473 ,
D00973 ,
D00975 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D01998 ,
D02156 ,
D02174 ,
D02591 ,
D02592 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
38Cystagon (cysteamine bitartrate) immediate-release capsules[1] Cysteamine (Synonym: PROCYSBI Delayed-release)[2] D03634 ,
D03635 		--[1] 299
39Cysteamine Bitartrate Delayed-release Capsules[1] Cysteamine (Synonym: PROCYSBI Delayed-release)[2] D03634 ,
D03635 		--[1] 19
40Cysteamine Bitartrate Delayed-release Capsules (RP103)[1] Cysteamine (Synonym: PROCYSBI Delayed-release)[2] D03634 ,
D03635 		--[1] 19
41D-methylphenidate
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 84
42Deferiprone 600 mg delayed release tablet[1] Deferiprone[1] D07416 --[1] 6
43Delayed and extended release mesalazine[1] Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)[1] D00377 --[1] 97
44Delayed Release 6 mercaptopurine[1] Mercaptopurine[2] D00161 ,
D04931 		[1] HPRT1 💬[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 96
45Delayed Release 6MP or Calcitriol vs. Purinethol[1] Calcitriol[1] D00129 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 96
46Diazoxide choline controlled-release tablet[2] Choline (Synonym: Complete Multivitamins and Minerals Tablets Timed Release),
Diazoxide		[2] D00294 ,
D07690 		[2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[1] 193
47Diclofenac
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
48Diclofenac + Omeprazole
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[2] Diclofenac (Synonym: Diclofenac Sodium Extended-Release),
Omeprazole (Synonym: Omeprazole Magnesium Delayed Release Tablets)		[7] D00455 ,
D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D01207 ,
D05259 ,
D05261 ,
D07816 		[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
49Diclofenac 50 milligrams
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
50Diclofenac Sodium
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 34, 46
51Diclofenac sodium topical gel
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 13
52Diclofenac SR
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
53Diltiazem
(Synonym: DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE)		[1] Diltiazem (Synonym: Diltiazem Hydrochloride Extended Release)[3] D00616 (Name: DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE),
D03830 ,
D07845 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
54Diltiazem Gel 2%
(Synonym: DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE)		[1] Diltiazem (Synonym: Diltiazem Hydrochloride Extended Release)[3] D00616 (Name: DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE),
D03830 ,
D07845 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
55Diltiazem Hydrochloride
(Synonym: DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE)		[1] Diltiazem (Synonym: Diltiazem Hydrochloride Extended Release)[3] D00616 (Name: DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE),
D03830 ,
D07845 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
56Dual release hydrocortisone (plenadren)[1] Hydrocortisone[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
57Efmody 10 mg modified release hard capsules[1] Manganese citrate (Synonym: Release)---[1] 81
58Efmody 5 mg modified release hard capsules[1] Manganese citrate (Synonym: Release)---[1] 81
59Epilim Chrono 200 Controlled Released tablets----[1] 256
60Epilim Chrono 300 Controlled Released tablets----[1] 256
61Epilim Chrono 500 Controlled Released tablets----[1] 256
62Exenatide extended release 2mg (Bydureon)[1] Exenatide[1] D04121 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 6
63Extended release dipyridamole 200mg/aspirin 25mg[2] Acetylsalicylic acid (Synonym: Aspirin Coated for Delayed Release Extra Strength),
Dipyridamole (Synonym: Aspirin and Dipyridamole Extended Release)		[2] D00109 ,
D00302 		[4] PDE4A,
PDE5A,
PTGS1,
PTGS2 💬		[28] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Purine metabolism, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 49
64Extended release fampridine[1] Dalfampridine[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
65Extended-release oxycodone[1] Oxycodone (Synonym: Oxycodone HCl Controlled-Release)[3] D03783 ,
D05312 ,
D05462 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 13
66Extended-release quetiapine fumarate[1] Quetiapine (Synonym: Quetiapine Fumarate Extended-Release)[2] D00458 ,
D08456 		[2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 13
67Fampyra 10 mg prolonged-release tablets[2] Dalfampridine,
Manganese citrate (Synonym: Release)		[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
68Fampyra 10mg prolonged release tablets[2] Dalfampridine,
Manganese citrate (Synonym: Release)		[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
69Firategrast immediate release tablet[1] Firategrast[1] D06590 [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13
70Firategrast modified release tablet[1] Firategrast[1] D06590 [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13
71Glatiramer acetate with minocycline
(Synonym: MINOLIRA EXTENDED RELEASE)		[3] Acetate,
Glatiramer,
Minocycline (Synonym: Minolira Extended Release)		[3] D00850 (Name: MINOLIRA EXTENDED RELEASE),
D04318 ,
D05045 		[20] HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬		[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬[1] 13
72Glucophage (metformin)
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[2] 46, 75
73Guanfacine
(Synonym: GUANFACINE EXTENDED-RELEASE)		[1] Guanfacine (Synonym: Guanfacine Extended-Release)[2] D00606 (Name: GUANFACINE EXTENDED-RELEASE),
D08031 		[1] ADRA2A 💬[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 193
74Guanfacine extended release (GXR)[1] Guanfacine (Synonym: Guanfacine Extended-Release)[2] D00606 (Name: GUANFACINE EXTENDED-RELEASE),
D08031 		[1] ADRA2A 💬[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 193
75Hydrocortisone Modified Release Capsules[1] Hydrocortisone[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
76IBD98-M Delayed-release Capsules[1] Manganese citrate (Synonym: Release)---[1] 97
77Immediate release carbidopa/levodopa[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
78Immediate Release carbidopa/levodopa 10/100 mg[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
79Immediate Release carbidopa/levodopa 25/100 mg[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
80Indomethacin
(Synonym: INDOMETHACIN EXTENDED-RELEASE)		[1] Indomethacin (Synonym: Indomethacin extended-release)[3] D00141 (Name: INDOMETHACIN EXTENDED-RELEASE),
D01565 ,
D02110 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298
81Intravenous Infusion of Diclofenac Sodium
(Synonym: DICLOFENAC SODIUM DELAYED RELEASE)		[1] Diclofenac (Synonym: Diclofenac Sodium Extended-Release)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM DELAYED RELEASE),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 78
82KVD824 300 mg Modified Release Tablets[1] Manganese citrate (Synonym: Release)---[1] 65
83L-Citrulline and Metformin & L-Citrulline
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[2] Citrulline,
Metformin (Synonym: Metformin Hydrochloride Extended-Release)		[3] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 ,
D07706 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 113
84Lamotrigine
(Synonym: LAMOTRIGINE EXTENDED RELEASE)		[1] Lamotrigine (Synonym: Lamotrigine Extended Release)[1] D00354 (Name: LAMOTRIGINE EXTENDED RELEASE)[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 13, 34, 38, 114, 144
85Lamotrigine - generic product
(Synonym: LAMOTRIGINE EXTENDED RELEASE)		[1] Lamotrigine (Synonym: Lamotrigine Extended Release)[1] D00354 (Name: LAMOTRIGINE EXTENDED RELEASE)[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 38
86Lamotrigine 25Mg Oral Tablet, Extended Release[1] Lamotrigine (Synonym: Lamotrigine Extended Release)[1] D00354 (Name: LAMOTRIGINE EXTENDED RELEASE)[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 114
87Lamotrigine dispers
(Synonym: LAMOTRIGINE EXTENDED RELEASE)		[1] Lamotrigine (Synonym: Lamotrigine Extended Release)[1] D00354 (Name: LAMOTRIGINE EXTENDED RELEASE)[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 34
88Lamotrigine extended release tablets[1] Lamotrigine (Synonym: Lamotrigine Extended Release)[1] D00354 (Name: LAMOTRIGINE EXTENDED RELEASE)[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13
89Levetiracetam
(Synonym: LEVETIRACETAM EXTENDED RELEASE)		[1] Levetiracetam (Synonym: LEVETIRACETAM Extended-release)[1] D00709 (Name: LEVETIRACETAM EXTENDED RELEASE)[1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
90Levodopa carbidopa (LC) oral encapsulated immediate release (IR) tablets[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
91Levodopa CR (controlled release)[1] Levodopa[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
92Levodopa-carbidopa (LC) oral encapsulated immediate release (IR) tablets[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
93Levodopa-carbidopa Immediate Release (LC-IR) Tablets[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
94Levodopa-Carbidopa Multilayer Extended Release Tablet[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
95Lodotra (delayed release prednisolone)[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 41
96Lovastatin, then Minocycline/Lovastatin
(Synonym: MINOLIRA EXTENDED RELEASE)		[2] Lovastatin,
Minocycline (Synonym: Minolira Extended Release)		[3] D00359 ,
D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 206
97LPM3770164 sustained release tablet[1] Manganese citrate (Synonym: Release)---[1] 8
98LPM3770164 sustained release tablet simulant[1] Manganese citrate (Synonym: Release)---[1] 8
99LT-02 (modified-release PC pellets)[1] Manganese citrate (Synonym: Release)---[1] 97
100LY03003 ( Rotigotine, extended-release microspheres)[1] Rotigotine[1] D05768 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
101LY03003 (rotigotine extended release microspheres for intramuscular [IM] injection)[1] Rotigotine[1] D05768 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
102LY03003(Rotigotine,extended-release microspheres)[1] Rotigotine[1] D05768 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
103Mesalamine Delayed Release Tablets 400mg[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
104Mesalazine slow-release granules[1] Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)[1] D00377 --[1] 97
105Mesalazine Sustained-Release Tablets[1] Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)[1] D00377 --[1] 96
106Metformin
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
107Metformin (generic)
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 158
108Metformin 500 mg TID Oral Tablet
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 97
109Metformin 500mg
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 113
110Metformin and Metformin & L-Citrulline
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[2] Citrulline,
Metformin (Synonym: Metformin Hydrochloride Extended-Release)		[3] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 ,
D07706 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 113
111Metformin HCl
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 285
112METFORMIN HYDROCHLORIDE
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[5] 81, 158, 265, 299, 301
113Metformin treatment
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 46
114Metformin XR
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 67
115Metformin/CP-690,550
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 46
116Methylphenidate
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206
117Methylphenidate (MPD)
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 6
118Methylphenidate (overencapsulated)
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 84
119Methylphenidate 10mg tablets
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 84
120METHYLPHENIDATE HYDROCHLORIDE
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[2] 6, 13
121Methylphenidate modified release[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13
122Methylphenidate modified release 20 mg[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13
123Methylphenidate modified release 30 mg[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13
124Methylphenidate modified release 40 mg[1] Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release)[2] D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13
125Methylphenidate, fluoxetin, risperidone
(Synonym: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		[3] Fluoxetine,
Methylphenidate (Synonym: Methylphenidate Hydrochloride Extended-Release),
Risperidone		[5] D00326 ,
D00426 ,
D00823 ,
D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE),
D04999 		[5] DRD2,
HTR2A,
SLC6A2,
SLC6A3,
SLC6A4 💬		[14] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Serotonergic synapse, Synaptic vesicle cycle, cAMP signaling pathway 💬[2] 179, 206
126Mezavant Gastro-resistant, prolonged release tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
127Mezavant XL 1200 mg gastro-resistant prolonged release tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
128Mezavant XL 1200 mg gastro-resistant, prolonged release tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
129Mezavant XL 1200 mg gastro-resistant, prolonged release tablets.[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
130Mezavant XL 1200mg gastro-resistant, prolonged release tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
131Mezavant XL Gastro-resistant, prolonged release tablets[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
132MG01CI extended-release tablet[1] Manganese citrate (Synonym: Release)---[1] 206
133Minocycline
(Synonym: MINOLIRA EXTENDED RELEASE)		[1] Minocycline (Synonym: Minolira Extended Release)[2] D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		--[13] 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
134Minocycline 100 mg Film-coated Tablets
(Synonym: MINOLIRA EXTENDED RELEASE)		[1] Minocycline (Synonym: Minolira Extended Release)[2] D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		--[1] 13
135Minocycline 100mg
(Synonym: MINOLIRA EXTENDED RELEASE)		[1] Minocycline (Synonym: Minolira Extended Release)[2] D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		--[1] 13
136Minocycline Hydrochloride
(Synonym: MINOLIRA EXTENDED RELEASE)		[1] Minocycline (Synonym: Minolira Extended Release)[2] D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		--[4] 13, 201, 206, 299
137Minocycline, then Minocycline/Lovastatin
(Synonym: MINOLIRA EXTENDED RELEASE)		[2] Lovastatin,
Minocycline (Synonym: Minolira Extended Release)		[3] D00359 ,
D00850 (Name: MINOLIRA EXTENDED RELEASE),
D05045 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 206
138Mirapexin extended release various strengths[2] Manganese citrate (Synonym: Release),
Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)		[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
139Modified-release phosphatidylcholine[2] Lecithin,
Manganese citrate (Synonym: Release)		[1] D04682 --[1] 97
140Nalbuphine Extended-Release (ER) Tablets[1] Nalbuphine[2] D00843 ,
D08246 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
141Naproxen (EC-Narosyn) Delayed Release Tables, 375 (Syntex (USA), Inc.)[1] Naproxen (Synonym: Naproxen delayed release)[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
142Naproxen Delayed Release Tables, 375 (Gevena Pharmaceuticals, Inc.)[1] Naproxen (Synonym: Naproxen delayed release)[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
143Octreotide LAR / Sandostatin LAR (LAR=long acting release)[1] Octreotide[2] D00442 ,
D06495 		[1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
144Oral treprostinil (UT-15C) Sustained Release Tablets[1] Treprostinil[1] D06213 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
145Other: Metformin
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[1] Metformin (Synonym: Metformin Hydrochloride Extended-Release)[2] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 46
146Oxybutynin, tolterodine, solifenacin
(Synonym: TOLTERODINE TARTRATE EXTENDED RELEASE)		[3] Oxybutynin (Synonym: Oxybutynin ChlorideExtended Release Extended Release),
Solifenacin,
Tolterodine (Synonym: Tolterodine Tartrate Extended Release)		[6] D00465 ,
D00646 ,
D00722 ,
D01148 (Name: TOLTERODINE TARTRATE EXTENDED RELEASE),
D01269 ,
D08522 		[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 53
147Oxycodone naloxone prolonged release tablets[2] Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
148Oxycodone/naloxone prolonged release t[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
149Oxycodone/Naloxone Prolonged Release tablets[2] Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
150Oxycodone/naloxone prolonged release tablets 10 mg /5 mg[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
151Oxycodone/naloxone prolonged release tablets 10/5 mg[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
152Oxycodone/naloxone prolonged release tablets 20 mg /10 mg[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
153Oxycodone/naloxone prolonged release tablets 20/10 mg[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
154Oxycodone/naloxone prolonged release tablets 5 mg /2.5 mg[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
155Oxycodone/naloxone prolonged release tablets 5/2.5 mg[3] Manganese citrate (Synonym: Release),
Naloxone,
Oxycodone (Synonym: Oxycodone HCl Controlled-Release)		[5] D01340 ,
D03783 ,
D05312 ,
D05462 ,
D08249 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226
156Pancrelipase Delayed Release[1] Pancrelipase[1] D05349 --[1] 299
157Pancrelipase Delayed Release Capsule[1] Pancrelipase[1] D05349 --[2] 298, 299
158Pentasa 2g sachet prolonged release granules (95%)[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
159Pentasa Compact 2g, granulate with prolonged release[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
160Pentasa Compact 4g, granulate with prolonged release[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
161Pentasa prolonged release granules 2g[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
162Pentasa Sachet 1 g prolonged release granules[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 96
163Pioglitazone or metformin
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[2] Metformin (Synonym: Metformin Hydrochloride Extended-Release),
Pioglitazone		[4] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D00945 ,
D04966 ,
D08378 		[3] PPARG,
PRKAA1,
PRKAA2 💬		[27] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Huntington disease, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Osteoclast differentiation, Oxytocin signaling pathway, PI3K-Akt signaling pathway, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Tight junction, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[1] 265
164Plenadren 20 mg modified-release tablets[2] Hydrocortisone,
Manganese citrate (Synonym: Release)		[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 78
165Plenadren 5 mg modified-release tablets[2] Hydrocortisone,
Manganese citrate (Synonym: Release)		[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 78
166Posaconazole Delayed Release Oral Tablet[1] Posaconazole[1] D02555 --[1] 96
167Pramipexol Extended Release[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
168Pramipexol Immediate Release[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
169Pramipexole dihydrochloride extended-release tablets[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
170Pramipexole dihydrochloride monohydrate extended release[2] Manganese citrate (Synonym: Release),
Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)		[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
171Pramipexole Extended Release[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
172Pramipexole extended release tablet[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
173Pramipexole hydrochloride sustained-release tablet (Siforl®) Specification: 0.26mg/ tablet (in pramipexole)[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
174Pramipexole Immediate Release[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
175Pramipexole immediate release tablet[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
176Praxol hydrochloride sustained release tablet Specification: 0.375mg/ tablet (in pramipexole hydrochloride)[1] Pramipexole (Synonym: Pramipexole Dihydrochloride Extended-Release)[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
177Pregabalin
(Synonym: PREGABALIN EXTENDED RELEASE)		[1] Pregabalin (Synonym: Pregabalin Extended Release)[1] D02716 (Name: PREGABALIN EXTENDED RELEASE)[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
178Pregabalin 75mg
(Synonym: PREGABALIN EXTENDED RELEASE)		[1] Pregabalin (Synonym: Pregabalin Extended Release)[1] D02716 (Name: PREGABALIN EXTENDED RELEASE)[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[1] 70
179Prolonged release tablet[1] Manganese citrate (Synonym: Release)---[1] 6
180Prolonged-release Fampridine[1] Dalfampridine[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
181Rabeprazole
(Synonym: RABEPRAZOLE SODIUM DELAYED-RELEASE)		[1] Rabeprazole (Synonym: Rabeprazole Sodium Delayed-release)[2] D00724 (Name: RABEPRAZOLE SODIUM DELAYED-RELEASE),
D08463 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
182Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die[1] Ranolazine[2] D05700 ,
D05701 		--[1] 58
183RAYOS (delayed-release prednisone)[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 46
184Release[1] Manganese citrate (Synonym: Release)---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
185Requip prolonged release[2] Manganese citrate (Synonym: Release),
Ropinirole		[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
186Requip XL prolonged-release[2] Manganese citrate (Synonym: Release),
Ropinirole		[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
187Retarded release phosphatidylcholine[1] Lecithin[1] D04682 --[1] 97
188Retarded Release Phosphatidylcholine (rPC)[1] Lecithin[1] D04682 --[1] 97
189Rifaximin Delayed Release (DR)[1] Rifaximin[1] D02554 --[1] 96
190Rifaximin delayed release 400 mg film coated tablet[1] Rifaximin[1] D02554 --[1] 96
191Rifaximin delayed release tablets[1] Rifaximin[1] D02554 --[1] 96
192Ropinirole controlled-release (REQUIP CR) for RLS[1] Ropinirole[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
193Ropinirole hydrochloride extended-release tablet[1] Ropinirole[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
194Ropinirole hydrochloride extended-release tablet placebo[1] Ropinirole[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
195Ropinirole hydrochloride prolonged release[2] Manganese citrate (Synonym: Release),
Ropinirole		[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
196Ropinirole immediate release[1] Ropinirole[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
197Ropinirole Prolonged release[1] Ropinirole[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
198Ropinirole prolonged release/extended release(PR/XR)[1] Ropinirole[2] D00784 ,
D08489 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
199Rosiglitazone Extended Release Tablets[1] Rosiglitazone[2] D00596 ,
D08491 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 46
200Rotigotine, extended-release microspheres[1] Rotigotine[1] D05768 [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
201Salofalk 3g gastro-resistant prolonged-release granules[2] Manganese citrate (Synonym: Release),
Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)		[1] D00377 --[1] 97
202Sinemet CR 25Mg-100Mg Extended-Release Tablet[3] Carbidopa,
Levodopa,
Manganese citrate (Synonym: Release)		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
203Sinemet® controlled release (Carbidopa/levodopa)[1] Carbidopa[1] D00558 [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[1] 6
204Sitagliptin and Metformin
(Synonym: METFORMIN HYDROCHLORIDE EXTENDED RELEASE)		[2] Metformin (Synonym: Metformin Hydrochloride Extended-Release),
Sitagliptin		[3] D00944 (Name: METFORMIN HYDROCHLORIDE EXTENDED RELEASE),
D04966 ,
D08516 		[3] DPP4,
PRKAA1,
PRKAA2 💬		[21] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Protein digestion and absorption, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 233
205SPD476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine[1] Mesalazine (Synonym: Pentasa Extended-release Tablets 250mg)[1] D00377 --[1] 97
206Sustained release growth hormone[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
207Sustained-release oral dalfampridine[1] Dalfampridine[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
208Sustained-release recombinant human GH (SR-rhGH)[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
209Tacrolimus prolonged-release hard capsules[2] Manganese citrate (Synonym: Release),
Tacrolimus		[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 299
210Targinact 10 mg/5 mg prolonged-release tablets[1] Manganese citrate (Synonym: Release)---[2] 6, 226
211Targinact 20 mg/10 mg prolonged-release tablets[1] Manganese citrate (Synonym: Release)---[1] 6
212Targinact 20mg/10 mg prolonged-release tablets[1] Manganese citrate (Synonym: Release)---[1] 226
213Targinact 5 mg/2.5 mg prolonged-release tablets[1] Manganese citrate (Synonym: Release)---[1] 6
214Targinact 5mg/2.5 mg prolonged-release tablets[1] Manganese citrate (Synonym: Release)---[1] 226
215Tofacitinib (Xeljanz®) 11mg Prolonged Release Tablet[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
216Tolterodine
(Synonym: TOLTERODINE TARTRATE EXTENDED RELEASE)		[1] Tolterodine (Synonym: Tolterodine Tartrate Extended Release)[2] D00646 ,
D01148 (Name: TOLTERODINE TARTRATE EXTENDED RELEASE)		[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53
217WD-1603 CARBIDOPA and LEVODOPA EXTENDED-RELEASE TABLETS[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
218WD-1603 Carbidopa-Levodopa Extended-Release Tablets[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
219WD-1603 CARBIDOPA/LEVODOPA EXTENDED-RELEASE TABLETS[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
220Wellbutrin (bupropion)
(Synonym: BUPROPION HYDROCHLORIDE EXTENDED RELEASE)		[1] Bupropion (Synonym: Bupropion Hydrochloride Extended Release)[3] D00817 (Name: BUPROPION HYDROCHLORIDE EXTENDED RELEASE),
D07591 ,
D07938 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 96
221Xeljanz® 11mg Prolonged Release Tablet[2] Manganese citrate (Synonym: Release),
Tofacitinib		[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46