Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1AAV1-gamma-sarcoglycan vector injection----[1] 113
2Alirocumab SAR236553 (REGN727)[1] Alirocumab[1] D10335 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
3Amitriptyline, fluoxetine and tramadol alone (control group)
(Synonym: Sarafem (TN))		[3] Amitriptyline,
Fluoxetine (Synonym: Sarafem),
Tramadol		[6] D00326 ,
D00809 ,
D00823 (Name: Sarafem (TN)),
D01355 ,
D07448 ,
D08623 		[3] OPRM1,
SLC6A2,
SLC6A4 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78
4BIVV020/SAR445088----[1] 14
5Etanercepet, Rituximab, Abatacept, Tocilizumab, Sarilumab[4] Abatacept,
Rituximab,
Sarilumab,
Tocilizumab		[4] D02596 ,
D02994 ,
D03203 ,
D10161 (Name: Sarilumab)		[4] CD80,
CD86,
IL6R,
MS4A1 💬		[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
6FLUOXETINE
(Synonym: Sarafem (TN))		[1] Fluoxetine (Synonym: Sarafem)[2] D00326 ,
D00823 (Name: Sarafem (TN))		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 13, 17, 78, 86
7FLUOXETINE HYDROCHLORIDE
(Synonym: Sarafem (TN))		[1] Fluoxetine (Synonym: Sarafem)[2] D00326 ,
D00823 (Name: Sarafem (TN))		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 13
8GM-CSF (granulocyte-macrophage colony-stimulating factor, sargramostim)[1] Sargramostim[1] D05803 (Name: Sargramostim)[1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[1] 229
9GM-CSF [Leukine (Sargramostim)][1] Sargramostim[1] D05803 (Name: Sargramostim)[1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[1] 229
10GZ/SAR402671----[2] 19, 67
11GZ402671 / SAR402671----[1] 19
12Isatuximab
(Synonym: Sarclisa (TN))		[1] Isatuximab (Synonym: Sarclisa)[1] D11050 (Name: Sarclisa (TN))[1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[2] 28, 61
13Isatuximab SAR650984[1] Isatuximab (Synonym: Sarclisa)[1] D11050 (Name: Sarclisa (TN))[1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[1] 61
14Lademirsen (SAR339375)----[1] 218
15Long term follow up in all patients who received SAR422459 in previous study TDU13583----[1] 301
16REGN475/SAR164877----[1] 298
17Sar----[1] 46
18SAR100842----[2] 51, 85
19SAR113244----[1] 49
20SAR153191[1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 41, 46, 107, 271
21SAR153191 (REGN88)[1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
22SAR156597----[2] 51, 85
23SAR231893----[2] 51, 160
24SAR236553----[1] 79
25SAR339375----[1] 218
26SAR339658----[2] 13, 97
27SAR402671, GZ402671 o GZ/SAR402671----[2] 19, 67
28SAR402671, GZ402671 or GZ / SAR402671----[1] 19
29SAR402671, GZ402671 or GZ/SAR402671----[3] 6, 19, 67
30SAR421869----[2] 90, 303
31SAR422459----[1] 301
32SAR439459----[1] 274
33SAR441344----[3] 13, 49, 53
34SAR441344 IV----[2] 13, 49
35SAR441344 SC----[2] 13, 49
36SAR442168----[2] 11, 13
37SAR443820----[1] 2
38SAR444671----[1] 61
39SAR445088 (formerly BIVV020)----[1] 14
40SAR650984----[1] 61
41Saracatinab----[1] 85
42Saracatinib[1] Saracatinib[1] D09664 (Name: Saracatinib)[2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[3] 6, 89, 272
43SARACATINIB DIFUMARATE[1] Saracatinib[1] D09664 (Name: Saracatinib)[2] ABL1,
SRC 💬		[49] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[1] 272
44Sarcosine[1] Sarcosine---[1] 6
45Sarcosine Capsule[1] Sarcosine---[1] 6
46Sargramostim[1] Sargramostim[1] D05803 (Name: Sargramostim)[1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[7] 6, 28, 60, 62, 96, 229, 285
47Sargramostim (Leukine)[1] Sargramostim[1] D05803 (Name: Sargramostim)[1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[1] 96
48SARILUMAB[1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[5] 41, 46, 84, 107, 271
49Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA][1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
50Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]_#1[1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 84
51Sarilumab SAR153191[1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
52Sarilumab SAR153191 (REGN88)[1] Sarilumab[1] D10161 (Name: Sarilumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
53SARIZOTAN[1] Sarizotan---[2] 6, 156
54Sarizotan HC1[1] Sarizotan---[1] 6
55Sarizotan HCl[1] Sarizotan---[1] 6
56Sarizotan Hydrochloride[1] Sarizotan---[2] 6, 156
57Saroglitazar[1] Saroglitazar---[1] 93
58Saroglitazar Magnesium 1 mg[2] Magnesium,
Saroglitazar		---[1] 93
59Saroglitazar Magnesium 2 mg[2] Magnesium,
Saroglitazar		---[1] 93
60Saroglitazar magnesium 4 mg[2] Magnesium,
Saroglitazar		---[1] 93
61SARS-COV-2 mRNA Vaccine[1] CVnCoV (Synonym: SARS-CoV-2 mRNA vaccine)---[1] 13
62Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)
(Synonym: Sarafem (TN))		[4] Amitriptyline,
Fluoxetine (Synonym: Sarafem),
Somatotropin,
Tramadol		[7] D00326 ,
D00809 ,
D00823 (Name: Sarafem (TN)),
D01355 ,
D02691 ,
D07448 ,
D08623 		[4] GHR,
OPRM1,
SLC6A2,
SLC6A4 💬		[9] Cytokine-cytokine receptor interaction, Estrogen signaling pathway, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78
63UshStat (SAR421869)----[2] 90, 303
64Venglustat GZ/SAR402671[1] Venglustat[1] D11633 [1] UGCG 💬[2] Metabolic pathways, Sphingolipid metabolism 💬[2] 6, 67
65Volixibat (formely SHP626, LUM002 or SAR548304B)[1] Volixibat[1] D11007 --[1] 94