Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
120 mg/ml Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
2Abatacept (ABA) + Methotrexate (MTX), double-blind (DB)
(Synonym: Trexall (TN))		[2] Abatacept,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D03203 		[4] CD80,
CD86,
DHFR,
DHFR2 💬		[17] Allograft rejection, Antifolate resistance, Autoimmune thyroid disease, Biosynthesis of cofactors, Cell adhesion molecules, Folate biosynthesis, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Metabolic pathways, One carbon pool by folate, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 46
3Abatacept + Methotrexate
(Synonym: Trexall (TN))		[2] Abatacept,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D03203 		[4] CD80,
CD86,
DHFR,
DHFR2 💬		[17] Allograft rejection, Antifolate resistance, Autoimmune thyroid disease, Biosynthesis of cofactors, Cell adhesion molecules, Folate biosynthesis, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Metabolic pathways, One carbon pool by folate, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 46
4Abatacept Active Treatment[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 50
5Abatacept Delayed-Onset Treatment[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 50
6Active Investigational Treatment ENT-01----[1] 6
7Active Treatment Group 7% Hypertonic Saline----[1] 299
8Adalimumab with methotrexate
(Synonym: Trexall (TN))		[2] Adalimumab,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02597 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
9Aesculus Hippocastanum / Horse Chestnut
(Synonym: Conker tree)		[1] Horse chestnut[1] D12028 (Name: Conker tree)--[1] 210
10All patients in the study will be treated with ocrelizumab[1] Ocrelizumab[1] D05218 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 13
11AZATHIOPRINE or METHOTREXATE
(Synonym: Trexall (TN))		[2] Azathioprine,
Methotrexate (Synonym: Trexall)		[4] D00142 ,
D00238 ,
D02115 (Name: Trexall (TN)),
D03033 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 96
12Background Treatment----[1] 46
13Baricitinib treatment[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
14Baseline Treatment----[1] 13
15BDMARD treatment----[1] 271
16Behavioral: CO-OP treatment protocol----[1] 6
17Behavioral: conservative treatment----[1] 291
18Behavioral: Tobacco Treatment Specialist (TTS) intervention[1] Tobacco leaf---[1] 299
19Bendamustine
(Synonym: Treanda (TN))		[1] Bendamustine (Synonym: Treanda)[1] D07501 (Name: Treanda (TN))--[2] 28, 61
20BENDAMUSTINE HYDROCHLORIDE
(Synonym: Treanda (TN))		[1] Bendamustine (Synonym: Treanda)[1] D07501 (Name: Treanda (TN))--[1] 61
21Bendamustine, Rituximab
(Synonym: Treanda (TN))		[2] Bendamustine (Synonym: Treanda),
Rituximab		[2] D02994 ,
D07501 (Name: Treanda (TN))		[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 61
22Best Medical Treatment----[1] 6
23Best médical treatment----[1] 6
24Bisphosphonate treatment----[2] 113, 299
25BMS-582949 and Methotrexate
(Synonym: Trexall (TN))		[2] BMS-582949,
Methotrexate (Synonym: Trexall)		[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
26Botulism Toxin Treatment----[1] 161
27Break in L-carnitine treatment[1] Levocarnitine[3] D02030 ,
D02176 ,
D04713 		--[1] 316
28Busulfan/Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF
(Synonym: Trexall (TN))		[6] Busulfan,
Filgrastim,
Fludarabine,
Methotrexate (Synonym: Trexall),
Phosphate ion,
Tacrolimus		[8] D00107 ,
D00142 ,
D00248 ,
D01907 ,
D02115 (Name: Trexall (TN)),
D03235 ,
D07966 ,
D08556 		[9] CSF3R,
DHFR,
DHFR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2,
RRM1 💬		[47] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, Axon guidance, B cell receptor signaling pathway, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Drug metabolism - other enzymes, Folate biosynthesis, Glucagon signaling pathway, Glutamatergic synapse, Glutathione metabolism, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, One carbon pool by folate, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Pyrimidine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 60
29C-Trelin OD Tab(5mg Taltirelin Hydrate)----[1] 18
30Carbidopa/levodopa, as prescribed by treating physician[2] Carbidopa,
Levodopa		[2] D00059 ,
D00558 		[6] DDC,
DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[16] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
31Certolizumab Pegol + Methotrexate (MTX)
(Synonym: Trexall (TN))		[2] Certolizumab pegol,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D03441 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
32CF patients with a G551D mutation and treated with Ivacaftor[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
33Chinese herbal medicine treatment----[1] 6
34Classic DMARDs treatment group----[1] 46
35Clobetasol propionate + Methotrexate
(Synonym: Trexall (TN))		[3] Clobetasol,
Clobetasol propionate,
Methotrexate (Synonym: Trexall)		[4] D00142 ,
D01272 ,
D02115 (Name: Trexall (TN)),
D07715 		[3] DHFR,
DHFR2,
NR3C1 💬		[6] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate 💬[1] 162
36Clobetasol Propionate cream treatment[2] Clobetasol,
Clobetasol propionate		[2] D01272 ,
D07715 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
37Combination Product: Active treatment with dual therapy----[1] 2
38Combination Product: Exercise, and methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
39Combination Product: Implantable System for Remodulin (treprostinil)[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
40Combination Product: Laser, exercise, and methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
41Combination Product: Methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
42Combination Product: Treprostinil via implanted pump[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
43Corticosteroid treatment (Methylprednisolone or prednisolone)[2] Methylprednisolone,
Prednisolone		[14] D00407 ,
D00472 ,
D00751 ,
D00979 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 64
44CP-690,550 + methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
45Crysvita (burosumab-twza) Treatment[1] Burosumab[1] D10913 [1] FGF23 💬[11] Breast cancer, Calcium signaling pathway, Gastric cancer, MAPK signaling pathway, Melanoma, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton 💬[1] 238
46Current lipid-lowering treatment----[1] 79
47Current treatment of AL-CM----[1] 28
48Cutaneous iontophoresis of treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 51
49Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids
(Synonym: Trexall (TN))		[3] Azathioprine,
Cyclophosphamide,
Methotrexate (Synonym: Trexall)		[6] D00142 ,
D00238 ,
D00287 ,
D02115 (Name: Trexall (TN)),
D03033 ,
D07760 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 44
50Cyclosporin, Methotrexate (GVHD prophylaxis)
(Synonym: Trexall (TN))		[2] Cyclosporine,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D00184 ,
D02115 (Name: Trexall (TN))		[7] DHFR,
DHFR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[38] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, Axon guidance, B cell receptor signaling pathway, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Folate biosynthesis, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, One carbon pool by folate, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 326
51Cytokine-treated Veto Cells----[1] 60
52Deferiprone treated[1] Deferiprone[1] D07416 --[1] 120
53Detoxifying agents for antineoplastic treatment----[2] 299, 337
54Dietanolamina de treprostinilo[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
55Disease modifying treatment (DMT)----[1] 13
56DMARDs (methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
57Dopamine agonist treatment[1] Dopamine[2] D00633 ,
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 74
58Doxorubicin, methotrexate, cyclophosphamide, L-asparaginase
(Synonym: Trexall (TN))		[4] Asparaginase Escherichia coli,
Cyclophosphamide,
Doxorubicin,
Methotrexate (Synonym: Trexall)		[6] D00142 ,
D00287 ,
D02115 (Name: Trexall (TN)),
D02997 ,
D03899 ,
D07760 		[4] DHFR,
DHFR2,
TOP2A,
TOP2B 💬		[6] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Platinum drug resistance 💬[1] 65
59Drug treatment----[4] 46, 51, 74, 271
60Early immunosuppressants (azathioprine, methotrexate)
(Synonym: Trexall (TN))		[2] Azathioprine,
Methotrexate (Synonym: Trexall)		[4] D00142 ,
D00238 ,
D02115 (Name: Trexall (TN)),
D03033 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 96
61ERA as specific PAH treatment----[1] 86
62Etanercept + Methotrexate
(Synonym: Trexall (TN))		[2] Etanercept,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D00742 ,
D02115 (Name: Trexall (TN))		[4] DHFR,
DHFR2,
LTA,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
63Etanercept , Methotrexate
(Synonym: Trexall (TN))		[2] Etanercept,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D00742 ,
D02115 (Name: Trexall (TN))		[4] DHFR,
DHFR2,
LTA,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
64Etanercept Treatment[1] Etanercept[1] D00742 [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
65Etanercept, methotrexate and depomedrone
(Synonym: Trexall (TN))		[2] Etanercept,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D00742 ,
D02115 (Name: Trexall (TN))		[4] DHFR,
DHFR2,
LTA,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
66Etanercept, Methotrexate, Prednisolone
(Synonym: Trexall (TN))		[3] Etanercept,
Methotrexate (Synonym: Trexall),
Prednisolone		[11] D00142 ,
D00472 ,
D00742 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02115 (Name: Trexall (TN)),
D02156 ,
D03301 		[5] DHFR,
DHFR2,
LTA,
NR3C1,
TNF 💬		[72] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 56
67Eutonic Treprostinil Solution[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
68Experimental (Non Immunosuppressive Symptomatic Treatment (NIST) and Rituximab)[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 222
69Exposure to one or more disease-modifying drug(s)(DMDs) used to treat MS----[1] 13
70Fibrate treatment----[1] 160
71Foliglurax 10 mg (treatment A)[1] Foliglurax---[1] 6
72Foliglurax 30 mg (treatment B)[1] Foliglurax---[1] 6
73Follow-up study of the treated cohort----[1] 193
74From August 2020 'no additional treatment'----[1] 51
75GENOTROPIN (Somatropin) is a growth hormone treatment. It is an exact copy of the natural growth hormone that our bodies make. The main difference is that GENOTROPIN is man-made.[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 193
76Glucocorticoid Treatment----[1] 41
77Golimumab treatment optimization.[1] Golimumab[1] D04358 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 97
78Group 1 or Orencia treated group[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 46
79GUSELKUMAB
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[5] 37, 41, 51, 96, 97
80Guselkumab 100 mg
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 37
81Guselkumab Dose 1
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[3] 51, 96, 97
82Guselkumab Dose 2
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[3] 51, 96, 97
83Guselkumab Dose 3
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 96
84Guselkumab Dose 4
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 96
85Guselkumab Dose 5
(Synonym: Tremfya (TN))		[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 96
86HCQ/CQ and CAB combined treatment----[1] 74
87Herbal treatment (SA100)----[1] 97
88Horse chestnut
(Synonym: Conker tree)		[1] Horse chestnut[1] D12028 (Name: Conker tree)--[1] 210
89Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment[1] Xenon[2] D01901 ,
D06339 		--[1] 85
90Hyperpolarized 129 Xenon Gas Comparing Progressive Pulmonary Fibrosis Treatment[1] Xenon[2] D01901 ,
D06339 		--[1] 85
91Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)
(Synonym: Trexall (TN))		[4] Azathioprine,
Methotrexate (Synonym: Trexall),
Mycophenolate mofetil,
Mycophenolic acid		[8] D00142 ,
D00238 ,
D00752 ,
D02115 (Name: Trexall (TN)),
D03033 ,
D05094 ,
D05095 ,
D05096 		[4] DHFR,
DHFR2,
IMPDH1,
IMPDH2 💬		[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism 💬[1] 49
92Immunosuppressive treatment----[1] 66
93Immunosuppressive treatment (eg, rituximab)[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 64
94Immunosuppressors (Thiopurines or Methotrexate)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 96
95In double-blind phase: treatment with tofacitinib[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 107
96In open-label phase: treatment with tofacitinib[1] Tofacitinib[1] D09970 [4] JAK1,
JAK2,
JAK3,
TYK2 💬		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 107
97In vitro-treated bone marrow transplantation----[1] 60
98In vitro-treated peripheral blood stem cell transplantation----[2] 60, 65
99Infliximab + methotrexate (MTX)
(Synonym: Trexall (TN))		[2] Infliximab,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02598 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
100Infliximab plus methotrexate
(Synonym: Trexall (TN))		[2] Infliximab,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02598 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 107
101Infliximab, methylprednisolone, methotrexate
(Synonym: Trexall (TN))		[3] Infliximab,
Methotrexate (Synonym: Trexall),
Methylprednisolone		[9] D00142 ,
D00407 ,
D00751 ,
D00979 ,
D02115 (Name: Trexall (TN)),
D02598 ,
D05000 ,
D05001 ,
D05002 		[4] DHFR,
DHFR2,
NR3C1,
TNF 💬		[72] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
102Inhaled dry powder treprostinil (LIQ861)[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
103Inhaled Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[3] 84, 85, 86
104Interferon beta treatment to add-on atorvastatin treatment[2] Atorvastatin,
Human interferon beta		[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 13
105Intrathecal methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 13
106Intravenous Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
107Intravenous/Subcutaneous Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
108Iontophoresis of treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 51
109IV treatment with IGSC, 10%----[1] 65
110L606 (Liposomal Treprostinil) Inhalation Solution 51ug[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
111Lapaquistat acetate and current lipid-lowering treatment[2] Acetate,
Lapaquistat		---[1] 79
112Large dose of prednisolone plus intra-lesional of Triamcinolone Acetonide followed the systemic combination of mycophenolate mofetil (MMF), dapsone and low dose prednisolone in treatment of MMP[5] Dapsone,
Mycophenolate mofetil,
Mycophenolic acid,
Prednisolone,
Triamcinolone (Synonym: Treziopak)		[18] D00385 ,
D00472 ,
D00592 ,
D00752 ,
D00980 ,
D00981 ,
D00982 ,
D00983 ,
D00984 ,
D00985 ,
D01239 ,
D01998 ,
D02156 ,
D03301 ,
D05094 ,
D05095 ,
D05096 ,
D06216 		[3] IMPDH1,
IMPDH2,
NR3C1 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism 💬[1] 162
113LIQ861 Inhaled Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
114Lumacaftor-Ivacaftor treatment[2] Ivacaftor,
Lumacaftor		[2] D09916 ,
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
115Metformin treatment[1] Metformin[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 46
116Methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
117Methotrexate 'Lederle' 2,5mg tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
118Methotrexate 'Lederle' 2.5mg Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
119Methotrexate 'Lederle' Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
120Methotrexate (Metoject® prefilled pen)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
121Methotrexate (MTX)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
122Methotrexate (stable dose)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
123Methotrexate (tapering dose)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
124Methotrexate + biologic administration
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
125Methotrexate + Infliximab
(Synonym: Trexall (TN))		[2] Infliximab,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02598 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
126Methotrexate + Methylprednisolone
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Methylprednisolone		[8] D00142 ,
D00407 ,
D00751 ,
D00979 ,
D02115 (Name: Trexall (TN)),
D05000 ,
D05001 ,
D05002 		[3] DHFR,
DHFR2,
NR3C1 💬		[6] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate 💬[1] 46
127Methotrexate + salazopyrine + hydroxychloroquine administration
(Synonym: Trexall (TN))		[2] Hydroxychloroquine,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D08050 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
128METHOTREXATE - 20 MG/0.8 ML SOLUZIONE INIETTABILE 4 SIRINGHE PRERIEMPITE MONOUSO DA 1.25 ML
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 96
129Methotrexate - Amneal
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
130Methotrexate - DAVA
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
131Methotrexate - Delay
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
132Methotrexate - etanercept - prednisolone arm
(Synonym: Trexall (TN))		[3] Etanercept,
Methotrexate (Synonym: Trexall),
Prednisolone		[11] D00142 ,
D00472 ,
D00742 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02115 (Name: Trexall (TN)),
D02156 ,
D03301 		[5] DHFR,
DHFR2,
LTA,
NR3C1,
TNF 💬		[72] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[2] 46, 107
133Methotrexate - Immediate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
134Methotrexate 10 mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
135Methotrexate 10 mg tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
136Methotrexate 2.5 mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 44
137METHOTREXATE 2.5 mg tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
138Methotrexate 2.5mg Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
139Methotrexate 2.5mg Tablets BP
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
140Methotrexate 25 mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 44
141Methotrexate 50mg/ml solution for injection, pre-filled syringe
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
142Methotrexate ``Lederle`` 2.5mg tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
143Methotrexate alone
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 107
144Methotrexate and folic acid
(Synonym: Trexall (TN))		[2] Folic acid,
Methotrexate (Synonym: Trexall)		[3] D00070 ,
D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 49
145Methotrexate as methotrexate disodium
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
146Methotrexate bellon
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 97
147Methotrexate bellon 25mg/ml
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 97
148Methotrexate capsules
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
149METHOTREXATE DISODIUM
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[5] 46, 96, 97, 107, 271
150Methotrexate Ebewe
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
151METHOTREXATE HOSPIRA 2,5 mg tablety
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
152METHOTREXATE HOSPIRA 2.5 mg tablety
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
153Methotrexate injection
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[2] 96, 97
154Methotrexate Lachema 5inj. sol
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 50
155Methotrexate Lederle 2.5 mg Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
156Methotrexate Pfizer 2,5 mg tabletter
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
157Methotrexate Placebo
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
158Methotrexate plus ENBREL or ENBREL alone
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
159Methotrexate plus ERB-041 for 12 weeks
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
160Methotrexate plus sulfasalazine
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Sulfasalazine		[3] D00142 ,
D00448 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
161Methotrexate pre-filled pen
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
162Methotrexate prefilled pen
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[2] 46, 107
163Methotrexate prefilled syringe
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
164METHOTREXATE SODIUM
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[2] 46, 256
165Methotrexate Sodium 2.5mg Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
166Methotrexate Sodium Tablets 2.5 mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
167Methotrexate Sodium Tablets 2.5mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
168Methotrexate Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 40
169Methotrexate tablets 2.5 mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
170Methotrexate treatment[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[2] 41, 46
171Methotrexate Wyeth 2,5mg
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 50
172Methotrexate Wyeth 2,5mg tbl.
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 50
173Methotrexate ® 2.5mg Tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
174Methotrexate(MTX)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
175Methotrexate(MTX) administration is at the discretion of the rheumatologist and no tradename is fixed by the protocol
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
176Methotrexate(MTX) administration is at the discretion of the rheumatologist and no tradename is fixed by the protocol.
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
177Methotrexate(necessary)
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
178METHOTREXATE*100CPR 2,5MG
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
179METHOTREXATE*10MG/1,33ML 4S
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
180METHOTREXATE*15MG/2ML 4SIR
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
181METHOTREXATE*2,5MG 25CPR
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
182METHOTREXATE*20MG/2,66ML 4S
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
183METHOTREXATE*25CPR 2,5MG
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[2] 46, 107
184METHOTREXATE*7,5MG/ML 4SIR.
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
185Methotrexate, Leucovorin and BMS-986142
(Synonym: Trexall (TN))		[3] BMS-986142,
Leucovorin,
Methotrexate (Synonym: Trexall)		[5] D00142 ,
D01211 ,
D02115 (Name: Trexall (TN)),
D07986 ,
D07987 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
186Methotrexate,Adalimumab
(Synonym: Trexall (TN))		[2] Adalimumab,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02597 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
187Methotrexate-Lachema
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
188Methotrexate-Sulfasalazine-Hydroxychloroquine
(Synonym: Trexall (TN))		[3] Hydroxychloroquine,
Methotrexate (Synonym: Trexall),
Sulfasalazine		[4] D00142 ,
D00448 ,
D02115 (Name: Trexall (TN)),
D08050 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
189Methotrexate® 2.5 mg tablets
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
190MK0812 / Duration of Treatment: 12 Weeks----[1] 46
191Monthly autologous Treg cells infusions + 3 times per week Interleukin-2 injections[1] Human interleukin-2---[1] 2
192MP-435(dose1) + Methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
193MSC treatment----[1] 49
194MSC treatment 01----[1] 96
195MSC treatment 02----[1] 96
196Mycophenolate mofetil,methotrexate
(Synonym: Trexall (TN))		[3] Methotrexate (Synonym: Trexall),
Mycophenolate mofetil,
Mycophenolic acid		[6] D00142 ,
D00752 ,
D02115 (Name: Trexall (TN)),
D05094 ,
D05095 ,
D05096 		[4] DHFR,
DHFR2,
IMPDH1,
IMPDH2 💬		[7] Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism 💬[3] 42, 43, 45
197Natalizumab treatment[1] Natalizumab[1] D06886 [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13
198Nifurtimox-Eflronithine Combination Treatment (NECT)[1] Nifurtimox[1] D00833 --[1] 65
199Nusinersen Treatments[1] Nusinersen[1] D10881 [1] SMN2 💬-[1] 3
200Nutrition treat----[1] 96
201Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi[4] Epoprostenol,
Iloprost,
Macitentan,
Selexipag		[5] D00106 ,
D01337 ,
D02721 ,
D09994 ,
D10135 		[3] EDNRA,
EDNRB,
PTGIR 💬		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
202OC oral solution treatment A----[1] 6
203OC oral solution treatment B----[1] 6
204OC oral solution treatment C----[1] 6
205OC oral solution treatment D----[1] 6
206Only 1 arm: treatment with MSC-AFP----[1] 96
207Optimized antiparkinsonian treatment----[1] 6
208Optimized oral treatment----[1] 6
209Oral anticoagulant treatment----[1] 86
210Oral methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
211Oral treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[2] 51, 86
212Oral treprostinil (UT-15C) Sustained Release Tablets[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
213Other Parkinson's Disease treatments----[1] 6
214Other: Adalimumab treatment[1] Adalimumab[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 151
215Other: At-home natalizumab treated MS patient[1] Natalizumab[1] D06886 [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13
216Other: Best Medical Treatment----[1] 6
217Other: CD-TREAT diet----[1] 96
218Other: Control wound treatment----[1] 36
219Other: Crohn's Disease TReatment-with-EATing diet (CD-TREAT diet)----[1] 96
220Other: current treatment----[1] 46
221Other: Dead Sea Solar and Water Treatment[1] Water[1] D00001 --[1] 46
222Other: Diet treatment----[1] 240
223Other: Group 2 (DMARDS treated group)----[1] 46
224Other: Intensify treatment with the existing drug----[2] 96, 97
225Other: Methotrexate therapy
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
226Other: Motor Assessments before taking regular PD treatment----[1] 6
227Other: Motor Assessments on regular PD treatment----[1] 6
228Other: Multidisciplinary intensive rehabilitation treatment----[1] 6
229Other: No active treatment----[1] 274
230Other: No anti-inflammatory treatment----[1] 271
231Other: No IT treatment----[1] 19
232Other: No treatment----[2] 53, 274
233Other: No Treatment Arm----[1] 13
234Other: No treatment given----[1] 78
235Other: Observation of Ocrelizumab as Treatment in RRMS Patients[1] Ocrelizumab[1] D05218 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 13
236Other: On-demand treatment----[1] 299
237Other: Other: Symptomatic treatment of ALS----[1] 2
238Other: SLE treatment----[1] 49
239Other: Standard steroid treatment----[1] 113
240Other: Standard Treatment----[1] 227
241Other: Standard treatment according to the Clinical protocols----[3] 49, 51, 235
242Other: Usual drug treatment of Parkinson's disease----[1] 6
243Ova-Treg----[1] 96
244Ovastat 1000 (Treosulfan injection)[1] Treosulfan[1] D07253 (Name: Treosulfan)--[1] 65
245Ovastat 5000 (Treosulfan injection)[1] Treosulfan[1] D07253 (Name: Treosulfan)--[1] 65
246Parenteral Remodulin (treprostinil) injection[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
247Patient treated with DMARD----[1] 46
248Pentoxifylline
(Synonym: Trental (TN))		[1] Pentoxifylline (Synonym: Trental)[1] D00501 (Name: Trental (TN))--[10] 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
249Phase 1: Methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
250Pioglitazone and Tretinoin[2] Pioglitazone,
Tretinoin		[3] D00094 (Name: Tretinoin),
D00945 ,
D08378 		[4] PML,
PPARG,
RARA,
RARB 💬		[21] AMPK signaling pathway, Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Huntington disease, Influenza A, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 2
251Plasma from healthy young people treatment + Riluzole[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[1] 2
252Pooled Plasma (Human), Solvent/Detergent Treated----[1] 64
253PPI treatment----[1] 299
254Prednisone and ustekinumab treatment[2] Prednisone,
Ustekinumab		[2] D00473 ,
D09214 		[4] IL12A,
IL12B,
IL23A,
NR3C1 💬		[29] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Neuroactive ligand-receptor interaction, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 41
255Prednisone treatment[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 41
256Probiotic treatment----[1] 294
257Propranolol treatment[1] Propranolol[2] D00483 ,
D08443 		[3] ADRB1,
ADRB2,
ADRB3 💬		[12] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 227
258Rapid Dose Titration Group of Subcutaneous Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
259Regular treatment----[1] 97
260Remodulin (treprostinil sodium)[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
261Remodulin® (treprostinil) 1 mg/ml solution for infusion[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
262Remodulin® (treprostinil) 10 mg/ml solution for infusion[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
263Remodulin® (treprostinil) 2.5 mg/ml solution for infusion[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
264Remodulin® (treprostinil) 5 mg/ml solution for infusion[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
265Repository Corticotropin Injection -Treatment Extension[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
266Response to anakinra associated with methotrexate
(Synonym: Trexall (TN))		[2] Anakinra,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02934 		[4] DHFR,
DHFR2,
IL1R1,
IL1R2 💬		[20] Amoebiasis, Antifolate resistance, Biosynthesis of cofactors, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Folate biosynthesis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Metabolic pathways, NF-kappa B signaling pathway, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[1] 46
267Response to infliximab associated with methotrexate
(Synonym: Trexall (TN))		[2] Infliximab,
Methotrexate (Synonym: Trexall)		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02598 		[3] DHFR,
DHFR2,
TNF 💬		[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
268Routine Treatment of CD----[1] 96
269Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)[4] Amitriptyline,
Fluoxetine,
Somatotropin,
Tramadol		[7] D00326 ,
D00809 ,
D00823 ,
D01355 ,
D02691 ,
D07448 ,
D08623 		[4] GHR,
OPRM1,
SLC6A2,
SLC6A4 💬		[9] Cytokine-cytokine receptor interaction, Estrogen signaling pathway, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78
270SC treatment with IGSC, 10% with rHuPH20 followed by IV/IGSC, 10% only (safety)----[1] 65
271SC treatment with IGSC, 10% with rHuPH20 followed by SC/IGSC, 10% only (safety)----[1] 65
272Simvastatin treatment for 28 days[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 299
273Slow Dose Titration Group of Subcutaneous Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
274SLS-005 Trehalose[1] Trehalose---[1] 2
275Somatropin - GH treated cohort[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 193
276Stable weekly dose of methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
277Standard of Care Treatment----[3] 53, 245, 246
278Standard Steroid Treatment----[1] 85
279Standard treatment with a conventional drug----[1] 13
280Standard-of-care treatment----[1] 49
281Standrd of Care treatment----[1] 64
282Study treatment PPI----[1] 166
283Subcutaneous Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
284Surgery treatment----[1] 291
285Symptomatic treatment (Converting Enzyme inhibitor, Angiotensin II, Anti-renin, Aldosterone antagonist diuretic, Beta blocker, Calcium inhibitor, statin)[3] Aldosterone,
Angiotensin II,
Calcium (Synonym: Restoration Treatment)		[3] D00150 ,
D02014 ,
D10528 		[3] AGTR1,
AGTR2,
NR3C2 💬		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
286Symptomatic Treatment, Steroids, Immunosuppressive Agents( azathioprine, tacrolimus, Mycophenolate Mofetil)[4] Azathioprine,
Mycophenolate mofetil,
Mycophenolic acid,
Tacrolimus		[8] D00107 ,
D00238 ,
D00752 ,
D03033 ,
D05094 ,
D05095 ,
D05096 ,
D08556 		[7] IMPDH1,
IMPDH2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[36] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 11
287Symptomatic Treatment, Steroids, Immunosuppressive Agents, Plasma Exchange(PE), Intravenous Immunoglobulin(IVIg)[1] Human immunoglobulin G---[1] 11
288Systemic non-biological treatments----[2] 46, 271
289Tacrolimus with Methotrexate
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tacrolimus		[4] D00107 ,
D00142 ,
D02115 (Name: Trexall (TN)),
D08556 		[7] DHFR,
DHFR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[38] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, Axon guidance, B cell receptor signaling pathway, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Folate biosynthesis, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, One carbon pool by folate, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
290TAK-715 and methotrexate
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
TAK-715		[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
291TAK-783 and methotrexate
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
292Tasocitinib plus Methotrexate
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tofacitinib		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D09970 		[6] DHFR,
DHFR2,
JAK1,
JAK2,
JAK3,
TYK2 💬		[42] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Antifolate resistance, Biosynthesis of cofactors, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Folate biosynthesis, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, Metabolic pathways, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, One carbon pool by folate, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
293The Comprehensive Treatment Regimen of Traditional Chinese Medicine----[1] 222
294The Standard Steroid Treatment, Plasma Exchange and rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 85
295Time delay treatment of botulinum toxin----[1] 149
296TL011, anti CD20, for the treatment of rheumatoid arthritis----[1] 46
297Tocilizumab + methotrexate(MTX)
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tocilizumab		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02596 		[3] DHFR,
DHFR2,
IL6R 💬		[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
298Tocilizumab plus methotrexate
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tocilizumab		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02596 		[3] DHFR,
DHFR2,
IL6R 💬		[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
299Tocilizumab treatment[1] Tocilizumab[1] D02596 [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
300Tocilizumab+Methotrexate(MTX)
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tocilizumab		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D02596 		[3] DHFR,
DHFR2,
IL6R 💬		[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
301Tofacitinib with methotrexate
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tofacitinib		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D09970 		[6] DHFR,
DHFR2,
JAK1,
JAK2,
JAK3,
TYK2 💬		[42] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Antifolate resistance, Biosynthesis of cofactors, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Folate biosynthesis, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, Metabolic pathways, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, One carbon pool by folate, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
302Tofacitinib without methotrexate
(Synonym: Trexall (TN))		[2] Methotrexate (Synonym: Trexall),
Tofacitinib		[3] D00142 ,
D02115 (Name: Trexall (TN)),
D09970 		[6] DHFR,
DHFR2,
JAK1,
JAK2,
JAK3,
TYK2 💬		[42] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Antifolate resistance, Biosynthesis of cofactors, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Folate biosynthesis, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, Metabolic pathways, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, One carbon pool by folate, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
303Topical Pentoxifylline Gel (Vehicle +PTX)
(Synonym: Trental (TN))		[1] Pentoxifylline (Synonym: Trental)[1] D00501 (Name: Trental (TN))--[1] 56
304TR004 (Treg immunotherapy)----[1] 96
305Traditional treatment of CGD and TB----[1] 65
306Traditional treatments----[1] 97
307Transsphenoidal surgery treatment----[1] 74
308TRE----[1] 86
309Treat to target----[1] 46
310Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms[1] Lansoprazole (Synonym: Rugby Heartburn Treatment)[1] D00355 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 98
311Treatment----[2] 41, 299
312Treatment A----[2] 34, 46
313Treatment according to current standards without knowledge of serum infliximab and anti-infliximab Ab status[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 96
314Treatment Algorithm A----[1] 97
315Treatment Algorithm B----[1] 97
316Treatment Algorithm C----[1] 97
317Treatment as Usual (TAU)----[1] 85
318Treatment B----[2] 34, 46
319Treatment BX1514M----[1] 58
320Treatment C----[2] 34, 46
321Treatment D----[1] 34
322Treatment defined only by active substance----[1] 50
323Treatment I----[1] 46
324Treatment II----[1] 46
325Treatment III----[1] 46
326Treatment intervention----[1] 61
327Treatment of MTX----[1] 46
328Treatment of MTX and HCQ----[1] 46
329Treatment of MTX and TwHF----[1] 46
330Treatment of TCM----[1] 46
331Treatment of TwHF----[1] 46
332Treatment Phase Group 4----[1] 113
333Treatment standard----[1] 61
334Treatment systemic therapy (prednisone)[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
335Treatment with Adalimumab[1] Adalimumab[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 96
336Treatment with azathioprin----[1] 95
337Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] D09916 ,
D10134 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
338Treatment with mycophenolat mofetil----[1] 95
339Treatment with polyethylene glycol (Macrogol 4000)[1] Polyethylene glycol[1] D03370 --[1] 299
340Treatment with systemic therapy (doxycycline)[1] Doxycycline[5] D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--[1] 162
341Treatment with systemic therapy (methotrexate)[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 162
342Treatment with systemic therapy (prednisone)[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
343Treatment with topical superpotent corticosteroid therapy----[1] 162
344Tregalizumab[1] Tregalizumab---[1] 46
345Trehalose[1] Trehalose---[2] 2, 113
346Trekking pole (TP).----[1] 13
347TREMFYA[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[2] 37, 97
348TREMFYA®[1] Guselkumab (Synonym: Tremfya One-press)[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[2] 37, 97
349TREOSULFAN[1] Treosulfan[1] D07253 (Name: Treosulfan)--[6] 13, 19, 62, 65, 283, 286
350Treprosinil Diethanolamine----[1] 86
351Treprostin----[1] 86
352Treprostinil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210
353Treprostinil dietanolamina[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
354Treprostinil diethanolamine[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[2] 51, 86
355Treprostinil Diolamine[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
356Treprostinil Inhalation Powder[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
357Treprostinil inhalations[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
358Treprostinil Injectable Product[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
359Treprostinil Palmitil[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
360TREPROSTINIL SODIUM[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[3] 51, 86, 88
361Treprostinil sodium for inhalation[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 85
362Treprostinil Sodium Solution for Inhalation[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
363TREPROSTINIL SODIUM, UT-15[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
364Treprostinil Ultrasonic Nebulizer[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 85
365Treprostinil, UT-15, LRX-15, 15AU81, BW A15AU, U-62, 840[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
366Treprostinilo[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
367Tretinoin[1] Tretinoin[1] D00094 (Name: Tretinoin)[3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[3] 2, 62, 75
368Tretinoin and Pioglitazone HCL[2] Pioglitazone,
Tretinoin		[3] D00094 (Name: Tretinoin),
D00945 ,
D08378 		[4] PML,
PPARG,
RARA,
RARB 💬		[21] AMPK signaling pathway, Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Huntington disease, Influenza A, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 2
369TRETINOINA[1] Tretinoin[1] D00094 (Name: Tretinoin)[3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 75
370Trexan----[2] 46, 97
371Trexan inj 25 mg/ml----[1] 97
372Trexan+Salazopyrin+Oxiklorin+prednisolone[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 46
373Trexan+Salazopyrin+Oxiklorin+prednisolone + infliximab[2] Infliximab,
Prednisolone		[9] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D02598 ,
D03301 		[2] NR3C1,
TNF 💬		[68] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
374Untreated to atorvastatin treatment[1] Atorvastatin[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 13
375Urine samples taken to measure methotrexate and its major metabolite 7-OH-methotrexate level
(Synonym: Trexall (TN))		[1] Methotrexate (Synonym: Trexall)[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
376Usual dopaminergic per os treatment----[1] 6
377UT-15C (treprostinil diethanolamine)[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
378UT-15C SR (treprostinil diethanolamine)[1] Treprostinil[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
379Vancomycin Pre-Treat[1] Vancomycin[2] D00212 ,
D00926 		--[1] 97
380Vancomycin Pre-Treatment[1] Vancomycin[2] D00212 ,
D00926 		--[1] 97
381Viral load driven treatment interruption----[1] 265