107. 若年性特発性関節炎 Juvenile idiopathic arthritis Clinical trials / Disease details
臨床試験数 : 441 / 薬物数 : 282 - (DrugBank : 56) / 標的遺伝子数 : 52 - 標的パスウェイ数 : 142
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01544114 (ClinicalTrials.gov) | April 2012 | 21/2/2012 | A Safety Study of VIMOVO in Adolescents With Juvenile Idiopathic Arthritis (JIA) | A 6-month, Multicenter, Open-label, Safety Study of VIMOVO (250 mg/20 mg, 375 mg/20 mg, and 500 mg/20 mg Naproxen/Esomeprazole) in Adolescents Aged 12 to 16 Years, Inclusive, With Juvenile Idiopathic Arthritis (JIA) | Juvenile Idiopathic Arthritis (JIA) | Drug: VIMOVO 250/20;Drug: VIMOVO 375/20;Drug: VIMOVO 500/20 | Horizon Pharma Ireland, Ltd., Dublin Ireland | NULL | Completed | 12 Years | 16 Years | All | 46 | Phase 4 | United States |
| 2 | NCT01358383 (ClinicalTrials.gov) | May 2011 | 16/5/2011 | Assessment of Pharmacokinetics of a Single Oral Dose of VIMOVO in Healthy Adult Volunteers | A Phase I, Open-label, Single-center Study to Assess the Pharmacokinetics of a Single Oral Dose of VIMOVO (250 mg Naproxen/20 mg Esomeprazole)in Healthy Adult Subjects | Juvenile Idiopathic Arthritis | Drug: naproxen;Drug: esomeprazole | AstraZeneca | NULL | Completed | 18 Years | 55 Years | Both | 28 | Phase 1 | United States |
| 3 | NCT00807846 (ClinicalTrials.gov) | September 2009 | 10/12/2008 | A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects | A Phase 4, 6-week, Randomized Double Blind, Multicenter, Active-controlled Trial To Evaluate The Effects Of Celecoxib (Celebrex) Or Naproxen On Blood Pressure In Pediatric Subjects With Juvenile Idiopathic Arthritis. | Arthritis, Juvenile Rheumatoid | Drug: Celecoxib;Drug: Naproxen | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | NULL | Completed | 2 Years | 17 Years | All | 201 | Phase 4 | United States;Chile;Costa Rica;Peru;Philippines;Russian Federation;Serbia;South Africa;Switzerland;Ukraine |
| 4 | EUCTR2014-003737-26-Outside-EU/EEA (EUCTR) | 07/04/2015 | A Phase 4, 6-week, randomized double-blind, multicenter, active-controlled trial to evaluate the effects of Celecoxib (Celebrex®) or Naproxen on blood pressure in paediatric subjects with juvenile idiopathic arthritis | A Phase 4, 6-week, randomized double-blind, multicenter, active-controlled trial to evaluate the effects of Celecoxib (Celebrex®) or Naproxen on blood pressure in paediatric subjects with juvenile idiopathic arthritis | Juvenile idiopathic arthritis;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] | Trade Name: Celebrex INN or Proposed INN: Celecoxib Other descriptive name: CELECOXIB INN or Proposed INN: Celecoxib Other descriptive name: CELECOXIB Product Name: Naproxen INN or Proposed INN: NAPROXEN SODIUM | Pfizer Inc | NULL | NA | Female: yes Male: yes | 201 | Phase 4 | South Africa;Ukraine;United States;Chile;Costa Rica;Peru;Philippines;Russian Federation;Serbia |